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Intraductal breast neoplasm

MedGen UID:
184927
Concept ID:
C0948967
Neoplastic Process
Synonyms: Breast Intraductal Neoplasm; Intraductal Breast Neoplasm; intraductal breast neoplasm
 
Monarch Initiative: MONDO:0002488

Definition

A benign or malignant epithelial neoplasm that arises anywhere in the ductal system of the breast. This category includes intraductal papilloma, intraductal papillary carcinoma, ductal hyperplasia with or without atypia, and ductal carcinoma in situ. [from NCI]

Professional guidelines

PubMed

Hudson-Phillips S, Cox K, Patel P, Al Sarakbi W
Br J Hosp Med (Lond) 2023 Jan 2;84(1):1-8. Epub 2023 Jan 24 doi: 10.12968/hmed.2022.0439. PMID: 36708338
Farante G, Toesca A, Magnoni F, Lissidini G, Vila J, Mastropasqua M, Viale G, Penco S, Cassano E, Lazzeroni M, Bonanni B, Leonardi MC, Ripoll-Orts F, Curigliano G, Orecchia R, Galimberti V, Veronesi P
Eur J Surg Oncol 2022 Apr;48(4):736-741. Epub 2021 Nov 9 doi: 10.1016/j.ejso.2021.10.030. PMID: 34772587
Brogi E, Krystel-Whittemore M
Mod Pathol 2021 Jan;34(Suppl 1):78-93. Epub 2020 Oct 26 doi: 10.1038/s41379-020-00706-5. PMID: 33106592

Curated

UK NICE Guideline NG101, Early and locally advanced breast cancer: diagnosis and management, 2024

Recent clinical studies

Etiology

Crimini E, Corti C, Repetto M, Giugliano F, Antonarelli G, Tarantino P, Zagami P, Morganti S, Nicolò E, Uliano J, Curigliano G
Chirurgia (Bucur) 2021 Dec;116(5 Suppl):S97-S104. doi: 10.21614/chirurgia.116.5.suppl.S97. PMID: 34967317
Brogi E, Krystel-Whittemore M
Mod Pathol 2021 Jan;34(Suppl 1):78-93. Epub 2020 Oct 26 doi: 10.1038/s41379-020-00706-5. PMID: 33106592
Feinberg J, Wetstone R, Greenstein D, Borgen P
Cancer Treat Res 2018;173:53-72. doi: 10.1007/978-3-319-70197-4_5. PMID: 29349758
Carlson RW, Edge SB, Theriault RL; NCCN Breast Cancer Practice Guidelines Panel
Cancer Control 2001 Nov-Dec;8(6 Suppl 2):54-61. PMID: 11760559
Simmons RM, Osborne MP
Surg Oncol 1999 Aug;8(2):55-65. doi: 10.1016/s0960-7404(99)00030-4. PMID: 10732957

Diagnosis

Brogi E, Krystel-Whittemore M
Mod Pathol 2021 Jan;34(Suppl 1):78-93. Epub 2020 Oct 26 doi: 10.1038/s41379-020-00706-5. PMID: 33106592
McCormick B, Winter K, Hudis C, Kuerer HM, Rakovitch E, Smith BL, Sneige N, Moughan J, Shah A, Germain I, Hartford AC, Rashtian A, Walker EM, Yuen A, Strom EA, Wilcox JL, Vallow LA, Small W Jr, Pu AT, Kerlin K, White J
J Clin Oncol 2015 Mar 1;33(7):709-15. Epub 2015 Jan 20 doi: 10.1200/JCO.2014.57.9029. PMID: 25605856Free PMC Article
Purushotham AD
Breast Cancer Res 2003;5(6):309-12. Epub 2003 Oct 9 doi: 10.1186/bcr649. PMID: 14580248Free PMC Article
Evans A
Breast Cancer Res 2003;5(5):250-3. Epub 2003 Jul 29 doi: 10.1186/bcr621. PMID: 12927034Free PMC Article
Kuhl CK
Eur Radiol 2000;10(1):46-58. doi: 10.1007/s003300050006. PMID: 10663717

Therapy

Kirova Y, Bouziane J, Loap P
Cancer Radiother 2024 Nov;28(6-7):510-512. Epub 2024 Sep 27 doi: 10.1016/j.canrad.2024.07.004. PMID: 39341690
McCormick B, Winter K, Hudis C, Kuerer HM, Rakovitch E, Smith BL, Sneige N, Moughan J, Shah A, Germain I, Hartford AC, Rashtian A, Walker EM, Yuen A, Strom EA, Wilcox JL, Vallow LA, Small W Jr, Pu AT, Kerlin K, White J
J Clin Oncol 2015 Mar 1;33(7):709-15. Epub 2015 Jan 20 doi: 10.1200/JCO.2014.57.9029. PMID: 25605856Free PMC Article
Independent UK Panel on Breast Cancer Screening
Lancet 2012 Nov 17;380(9855):1778-86. Epub 2012 Oct 30 doi: 10.1016/S0140-6736(12)61611-0. PMID: 23117178
Newman LA, Kuerer HM
J Clin Oncol 2005 Mar 10;23(8):1685-97. doi: 10.1200/JCO.2005.09.046. PMID: 15755977
Henry-Tillman RS, Klimberg VS
Curr Treat Options Oncol 2000 Aug;1(3):199-209. doi: 10.1007/s11864-000-0031-z. PMID: 12057162

Prognosis

Lorentzen EH, Chen YJ, Jin G, King TA, Mittendorf EA, Minami CA
Ann Surg Oncol 2024 Oct;31(10):6812-6819. Epub 2024 Jul 20 doi: 10.1245/s10434-024-15894-6. PMID: 39031264
Sokol ES, Feng YX, Jin DX, Tizabi MD, Miller DH, Cohen MA, Sanduja S, Reinhardt F, Pandey J, Superville DA, Jaenisch R, Gupta PB
Proc Natl Acad Sci U S A 2017 Apr 18;114(16):4153-4158. Epub 2017 Apr 4 doi: 10.1073/pnas.1703931114. PMID: 28377514Free PMC Article
Simmons RM, Osborne MP
Surg Oncol 1999 Aug;8(2):55-65. doi: 10.1016/s0960-7404(99)00030-4. PMID: 10732957
Toikkanen S, Eerola E, Ekfors TO
J Clin Pathol 1988 Mar;41(3):300-3. doi: 10.1136/jcp.41.3.300. PMID: 2834422Free PMC Article
Rosen PP
Monogr Pathol 1984;(25):59-105. PMID: 6330539

Clinical prediction guides

Van Bockstal MR, Berlière M, Duhoux FP, Galant C
Am J Clin Pathol 2020 Oct 13;154(5):596-609. doi: 10.1093/ajcp/aqaa077. PMID: 32566938
Alghamdi SA, Krishnamurthy K, Garces Narvaez SA, Algashaamy KJ, Aoun J, Reis IM, Recine MA, Jorda M, Poppiti RJ, Gomez-Fernandez CR
Am J Clin Pathol 2020 Feb 8;153(3):360-367. doi: 10.1093/ajcp/aqz179. PMID: 31769792
Feinberg J, Wetstone R, Greenstein D, Borgen P
Cancer Treat Res 2018;173:53-72. doi: 10.1007/978-3-319-70197-4_5. PMID: 29349758
Ross DS, Wen YH, Brogi E
Adv Anat Pathol 2013 Jul;20(4):205-16. doi: 10.1097/PAP.0b013e3182976ed5. PMID: 23752083
D'Orsi CJ
J Natl Cancer Inst Monogr 2010;2010(41):214-7. doi: 10.1093/jncimonographs/lgq037. PMID: 20956833Free PMC Article

Recent systematic reviews

Keating N, Cevik J, Hopkins D, Lippey J
J Surg Oncol 2024 May;129(6):1025-1033. Epub 2024 Feb 2 doi: 10.1002/jso.27592. PMID: 38305061
Hickey BE, Lehman M
Cochrane Database Syst Rev 2021 Aug 30;8(8):CD007077. doi: 10.1002/14651858.CD007077.pub4. PMID: 34459500Free PMC Article
Bundred J, Michael S, Bowers S, Barnes N, Jauhari Y, Plant D, Maishman T, Cutress R, Holleczek B, Dodwell D, Bundred N
Eur J Surg Oncol 2020 Dec;46(12):2185-2194. Epub 2020 Aug 28 doi: 10.1016/j.ejso.2020.08.015. PMID: 32907774
Aronsson L, Bengtsson A, Torén W, Andersson R, Ansari D
Int J Surg 2019 Nov;71:91-99. Epub 2019 Sep 20 doi: 10.1016/j.ijsu.2019.09.014. PMID: 31546033
Uematsu T
Breast Cancer 2012 Oct;19(4):295-301. Epub 2012 Mar 29 doi: 10.1007/s12282-012-0364-z. PMID: 22456924

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2024
      UK NICE Guideline NG101, Early and locally advanced breast cancer: diagnosis and management, 2024

    Consumer resources

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