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Recurrent Hereditary Thyroid Gland Medullary Carcinoma

MedGen UID:
1756444
•Concept ID:
C5420316
•
Neoplastic Process

Definition

The reemergence of hereditary thyroid gland medullary carcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Hereditary Thyroid Gland Medullary Carcinoma

Professional guidelines

PubMed

Diagnosis, treatment, and follow-up of medullary thyroid carcinoma: recommendations by the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism.
Maia AL, Siqueira DR, Kulcsar MA, Tincani AJ, Mazeto GM, Maciel LM
Arq Bras Endocrinol Metabol 2014 Oct;58(7):667-700. doi: 10.1590/0004-2730000003427. PMID: 25372577
Timing and extent of thyroid surgery for gene carriers of hereditary C cell disease--a consensus statement of the European Society of Endocrine Surgeons (ESES).
Niederle B, Sebag F, Brauckhoff M
Langenbecks Arch Surg 2014 Feb;399(2):185-97. Epub 2013 Dec 3 doi: 10.1007/s00423-013-1139-5. PMID: 24297502
Management of microcarcinomas (papillary and medullary) of the thyroid.
Wu LS, Milan SA
Curr Opin Oncol 2013 Jan;25(1):27-32. doi: 10.1097/CCO.0b013e328359feea. PMID: 23042124

Recent clinical studies

Etiology

Diagnosis, treatment, and follow-up of medullary thyroid carcinoma: recommendations by the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism.
Maia AL, Siqueira DR, Kulcsar MA, Tincani AJ, Mazeto GM, Maciel LM
Arq Bras Endocrinol Metabol 2014 Oct;58(7):667-700. doi: 10.1590/0004-2730000003427. PMID: 25372577
Timing and extent of thyroid surgery for gene carriers of hereditary C cell disease--a consensus statement of the European Society of Endocrine Surgeons (ESES).
Niederle B, Sebag F, Brauckhoff M
Langenbecks Arch Surg 2014 Feb;399(2):185-97. Epub 2013 Dec 3 doi: 10.1007/s00423-013-1139-5. PMID: 24297502
Management of microcarcinomas (papillary and medullary) of the thyroid.
Wu LS, Milan SA
Curr Opin Oncol 2013 Jan;25(1):27-32. doi: 10.1097/CCO.0b013e328359feea. PMID: 23042124
Multiple endocrine neoplasia type 2.
Gertner ME, Kebebew E
Curr Treat Options Oncol 2004 Aug;5(4):315-25. doi: 10.1007/s11864-004-0022-6. PMID: 15233908
An update on thyroid surgery.
Gimm O, Brauckhoff M, Thanh PN, Sekulla C, Dralle H
Eur J Nucl Med Mol Imaging 2002 Aug;29 Suppl 2:S447-52. Epub 2002 Jul 11 doi: 10.1007/s00259-002-0913-3. PMID: 12192544

Diagnosis

An Unusual Case of Medullary Thyroid Carcinoma and A Revision of Current Literature.
Cipri C, Vescini F, Torresan F, Pennelli G, Pelizzo MR, Triggiani V, Guastamacchia E, Grimaldi F
Endocr Metab Immune Disord Drug Targets 2019;19(2):226-229. doi: 10.2174/1871530319666181220165350. PMID: 30574858Free PMC Article
Surgical approaches in hereditary endocrine tumors.
Iacobone M, Citton M, Viel G, Schiavone D, Torresan F
Updates Surg 2017 Jun;69(2):181-191. Epub 2017 Apr 28 doi: 10.1007/s13304-017-0451-y. PMID: 28455835
Diagnosis, treatment, and follow-up of medullary thyroid carcinoma: recommendations by the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism.
Maia AL, Siqueira DR, Kulcsar MA, Tincani AJ, Mazeto GM, Maciel LM
Arq Bras Endocrinol Metabol 2014 Oct;58(7):667-700. doi: 10.1590/0004-2730000003427. PMID: 25372577
Management of microcarcinomas (papillary and medullary) of the thyroid.
Wu LS, Milan SA
Curr Opin Oncol 2013 Jan;25(1):27-32. doi: 10.1097/CCO.0b013e328359feea. PMID: 23042124
Multiple endocrine neoplasia type 2.
Gertner ME, Kebebew E
Curr Treat Options Oncol 2004 Aug;5(4):315-25. doi: 10.1007/s11864-004-0022-6. PMID: 15233908

Therapy

Disease impacts more than age on operative morbidity in children with Graves' disease after total thyroidectomy.
Machens A, Elwerr M, Schneider R, Lorenz K, Dralle H
Surgery 2018 Nov;164(5):993-997. Epub 2018 Aug 31 doi: 10.1016/j.surg.2018.07.021. PMID: 30174139
Management of microcarcinomas (papillary and medullary) of the thyroid.
Wu LS, Milan SA
Curr Opin Oncol 2013 Jan;25(1):27-32. doi: 10.1097/CCO.0b013e328359feea. PMID: 23042124
Multiple endocrine neoplasia type 2.
Gertner ME, Kebebew E
Curr Treat Options Oncol 2004 Aug;5(4):315-25. doi: 10.1007/s11864-004-0022-6. PMID: 15233908
An update on thyroid surgery.
Gimm O, Brauckhoff M, Thanh PN, Sekulla C, Dralle H
Eur J Nucl Med Mol Imaging 2002 Aug;29 Suppl 2:S447-52. Epub 2002 Jul 11 doi: 10.1007/s00259-002-0913-3. PMID: 12192544

Prognosis

Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: an international, multicentre, retrospective study.
Castinetti F, Waguespack SG, Machens A, Uchino S, Hasse-Lazar K, Sanso G, Else T, Dvorakova S, Qi XP, Elisei R, Maia AL, Glod J, Lourenço DM Jr, Valdes N, Mathiesen J, Wohllk N, Bandgar TR, Drui D, Korbonits M, Druce MR, Brain C, Kurzawinski T, Patocs A, Bugalho MJ, Lacroix A, Caron P, Fainstein-Day P, Borson Chazot F, Klein M, Links TP, Letizia C, Fugazzola L, Chabre O, Canu L, Cohen R, Tabarin A, Spehar Uroic A, Maiter D, Laboureau S, Mian C, Peczkowska M, Sebag F, Brue T, Mirebeau-Prunier D, Leclerc L, Bausch B, Berdelou A, Sukurai A, Vlcek P, Krajewska J, Barontini M, Vaz Ferreira Vargas C, Valerio L, Ceolin L, Akshintala S, Hoff A, Godballe C, Jarzab B, Jimenez C, Eng C, Imai T, Schlumberger M, Grubbs E, Dralle H, Neumann HP, Baudin E
Lancet Diabetes Endocrinol 2019 Mar;7(3):213-220. Epub 2019 Jan 16 doi: 10.1016/S2213-8587(18)30336-X. PMID: 30660595Free PMC Article
Diagnosis, treatment, and follow-up of medullary thyroid carcinoma: recommendations by the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism.
Maia AL, Siqueira DR, Kulcsar MA, Tincani AJ, Mazeto GM, Maciel LM
Arq Bras Endocrinol Metabol 2014 Oct;58(7):667-700. doi: 10.1590/0004-2730000003427. PMID: 25372577
Timing and extent of thyroid surgery for gene carriers of hereditary C cell disease--a consensus statement of the European Society of Endocrine Surgeons (ESES).
Niederle B, Sebag F, Brauckhoff M
Langenbecks Arch Surg 2014 Feb;399(2):185-97. Epub 2013 Dec 3 doi: 10.1007/s00423-013-1139-5. PMID: 24297502
Medullary thyroid carcinoma.
Brauckhoff M, Lorenz K, Ukkat J, Brauckhoff K, Gimm O, Dralle H
Scand J Surg 2004;93(4):249-60. doi: 10.1177/145749690409300402. PMID: 15658665
Multiple endocrine neoplasia type 2.
Gertner ME, Kebebew E
Curr Treat Options Oncol 2004 Aug;5(4):315-25. doi: 10.1007/s11864-004-0022-6. PMID: 15233908

Clinical prediction guides

Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer.
Scollo C, Baudin E, Travagli JP, Caillou B, Bellon N, Leboulleux S, Schlumberger M
J Clin Endocrinol Metab 2003 May;88(5):2070-5. doi: 10.1210/jc.2002-021713. PMID: 12727956
Pheochromocytoma: inherited associations, bilaterality, and cortex preservation.
Inabnet WB, Caragliano P, Pertsemlidis D
Surgery 2000 Dec;128(6):1007-11;discussion 1011-2. doi: 10.1067/msy.2000.110846. PMID: 11114636
Surgical treatment of medullary carcinoma of the thyroid.
Block MA
Otolaryngol Clin North Am 1990 Jun;23(3):453-73. PMID: 1973281

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