SEARCH STRATEGIES FOR THE IDENTIFICATION OF HEALTH ECONOMICS EVIDENCE

National Collaborating Centre for Mental Health (UK)

1. GENERAL SEARCH FILTERS

Drug misuse

a. CINAHL, HMIC, EMBASE, MEDLINE, PsycINFO – OVID interface

1	exp narcotic dependence/or exp opioid-related disorders/
2	(addiction or analgesic agent abuse or drug abuse or drug abuse pattern or drug dependenc$ or drug misuse or intravenous drug abuse or psychoses, substance-induced or substance abuse, intravenous or substance abuse, perinatal or substance abuse or substance dependence or substance withdrawal syndrome or substance-related disorders).sh.
3	“substance use disorders”/
4	((drug$1 or substance$) adj3 (abstain$ or abstinen$ or abus$ or addict$ or dependen$ or disorder$ or intoxicat$ or misus$ or over dos$ or overdos$ or use$2 or using or withdraw$)).tw.
5	or/1–4
6	diamorphine/or exp heroin/or morphine/
7	exp narcotic agent/or exp narcotics/or exp narcotic drugs/
8	(acetomorphine or diacephine or diacetylmorphine or diamorphine or diaphorin or heroin$ or morphacetin or morphine).mp. or 1502-95-0, 561-27-3.rn.
9	(anpec or duromorph or epimorph or morfin$ or morphia or morphin$ or morphinium or morphium or opso$1 or skenan).mp. or 57-27-2.rn.
10	opiate$.mp. or 8008-60-4.rn.
11	(opioid$ or opium or narcotic$).tw.
12	(abstain$ or abstinen$ or abus$ or addict$ or (excessive adj use$) or dependen$ or (inject$ adj2 drug$) or intoxicat$ or misus$ or over dos$ or overdos$ or (use$ adj (disorder$ or illicit)) or withdraw$).mp.
13	(or/6–11) and 12
14	or/5,13

b. NHS Economic Evaluation Database (NHS EED), Health Technology Assessment Database (HTA) – Wiley Interscience interface

1	MeSH descriptor Opioid-Related Disorders explode all trees
2	MeSH descriptor Substance-Related Disorders, this term only
3	MeSH descriptor Substance Abuse, Intravenous, this term only
4	MeSH descriptor Substance Withdrawal Syndrome, this term only
5	MeSH descriptor Psychoses, Substance-Induced, this term only
6	(drug* or substance) near (abstain or abstinen* or abus* or addict* or dependen* or disorder* or intoxicat* or misuse* or over dos* or overdos* or use or user* or using or withdraw):ti or (drug or substance) near (abstain or abstinen* or abus* or addict* or dependen* or disorder* or intoxicat* or misuse* or over dos* or overdos* or use or user* or using or withdraw):ab or (drug or substance) near (abstain or abstinen* or abus* or addict* or dependen* or disorder* or intoxicat* or misuse* or over dos* or overdos* or use or user* or using or withdraw*):kw
7	(#1 OR #2 OR #3 OR #4 OR #5 OR #6)
8	MeSH descriptor Heroin, this term only
9	MeSH descriptor Morphine explode all trees
10	MeSH descriptor Narcotics explode all trees
11	(acetomorphine or diacephine or diacetylmorphine or diamorphine or diaphorin or heroin* or morphacetin or morphin):ti or (acetomorphine or diacephine or diacetylmorphine or diamorphine or diaphorin or heroin or morphacetin or morphin):ab or (acetomorphine or diacephine or diacetylmorphine or diamorphine or diaphorin or heroin or morphacetin or morphin*):kw
12	(anpec or duromorph or epimorph or morfin* or morphia or morphin* or morphinium or morphium or opso* or skenan):ti or (anpec or duromorph or epimorph or morfin* or morphia or morphin* or morphinium or morphium or opso* or skenan):ab or (anpec or duromorph or epimorph or morfin* or morphia or morphin* or morphinium or morphium or opso* or skenan):kw
13	(opiate):ti or (opiate):ab or (opiate*):kw
14	(opioid* or opium or narcotic):ti or (opioid or opium or narcotic):ab or (opioid or opium or narcotic*):kw
15	(abstain* or abstinen* or abus* or addict* or (drug near use) or (excessive near use) or dependen or (inject* near drug) or intoxicat or misus* or over dos* or overdos* or (use* near (disorder* or illicit)) or withdraw):ti or (abstain or abstinen* or abus* or addict* or (drug near use) or (excessive near use) or dependen or (inject* near drug) or intoxicat or misus* or over dos* or overdos* or (use* near (disorder* or illicit)) or withdraw):ab or (abstain or abstinen* or abus* or addict* or (drug near use) or (excessive near use) or dependen or (inject* near drug) or intoxicat or misus* or over dos* or overdos* or (use* near (disorder* or illicit)) or withdraw*):kw
16	((#8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14) AND #15)
17	(#7 OR #16)

c. Health Economic Evaluations Database (OHE HEED) – Wiley interface

1	AX = (stimulant* or drug* or substance) and (abstain* or abstinen* or abus* or addict* or dependen* or detox* or disorder* or intoxicat* or misuse* or overdos* or use* or using* or withdraw*)
2	AX = acetomorphine or diacephine or diacetylmorphine or diamorphine or diaphorin or heroin or morphacetin or morphine
3	AX = anpec or duromorph or epimorph or morfin* or morphia or morphin or morphinium or morphium or opso* or skenan
4	AX = opioid* or opium or narcotic* or opiate*
5	AX = abstain* or abstinen* or abus* or addict* or dependen* or intoxicat* or misus* or overdos* or withdraw* or ‘disorder within 1 use’ or ‘disorder within 1 user’ or ‘disorder within 1 using’ or ‘disorders within 1 use’ or ‘disorders within 1 user’ or ‘disorders within 1 using’ or ‘drug within 2 use’ or ‘drug within 2 user’ or ‘excessive within 2 use’ or ‘excessive within 2 user’ or ‘excessively within 2 use’ or ‘excessively within 2 user’ or ‘illicit within 1 use’ or ‘illicit within 1 user’ or ‘illicit within 1 using’ or ‘illicitly within 1 use’ ‘illicitly within 1 user’ or ‘illicitly within 1 using’ or ‘inject drug’ or ‘inject drugs’ or ‘injecting drug’ or ‘injecting drugs’
6	CS = 2 OR 3 OR 4
7	CS = 5 AND 6
8	CS = 1 OR 7

2. HEALTH ECONOMIC AND QUALITY OF LIFE FILTERS

1	exp “costs and cost analysis”/or “health care costs”/
2	exp health resource allocation/or exp health resource utilization/
3	exp economics/or exp economic aspect/or exp health economics/
4	exp value of life/
5	(burden adj5 (disease or illness)).tw.
6	(cost or costs or costly or costing or price or prices or pricing or pharmacoeconomic$ or expenditure$ or economic$).tw.
7	(fiscal or funding or financial or finance or budget).tw.
8	(resource adj5 (allocation$ or utility$)).tw.
9	or/1–8
10	(value adj5 money).tw.
11	exp quality of life/
12	(qualit$3 adj5 (life or survival)).tw.
13	(wellbeing or health status or QOL).tw.
14	or/9–13

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Bookshelf ID: NBK50617

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Drug Misuse: Opioid Detoxification.

APPENDIX 11SEARCH STRATEGIES FOR THE IDENTIFICATION OF HEALTH ECONOMICS EVIDENCE

1. GENERAL SEARCH FILTERS

Drug misuse

2. HEALTH ECONOMIC AND QUALITY OF LIFE FILTERS

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