U.S. flag

An official website of the United States government

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

School of Health and Related Research (ScHARR), University of Sheffield. Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care [Internet]. Sheffield (UK): University of Sheffield; 2004 May. (NICE Clinical Guidelines, No. 14.)

  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

Cover of Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care

Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care [Internet].

Show details

10Research issues

This subject would benefit from further research in most areas. The guideline development group identified the following areas which they felt would help improve the evidence base for future versions of this guideline.

  1. Validation of risk assessment models is urgently needed.
  2. Different risk communication strategies should be evaluated.
  3. Prospective studies are needed of the short and long terms psychosocial and sexual impact of risk reducing surgery in women with a family history of breast cancer.
  4. Costs and benefits of surveillance in the 30–40 years age groups should be assessed by national pooling of all UK data.
  5. The effectiveness of MRI as a surveillance technique, especially in high risk women/gene carriers.
  6. The effectiveness of surveillance, in particular mammography, in those aged 40–49 years.
  7. Endocrine prevention studies (tamoxifen, aromatase inhibitors) would be valuable.
  8. Relative effectiveness of different methods of gene mutation testing.
  9. The role and usefulness of computer packages in risk assessment, audit and other aspects of care would be useful.
Copyright © 2004, School of Health and Related Research (ScHARR), University of Sheffield.
Bookshelf ID: NBK65454

Views

  • PubReader
  • Print View
  • Cite this Page
  • PDF version of this title (7.0M)
  • Disable Glossary Links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...