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School of Health and Related Research (ScHARR), University of Sheffield. Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care [Internet]. Sheffield (UK): University of Sheffield; 2004 May. (NICE Clinical Guidelines, No. 14.)
This publication is provided for historical reference only and the information may be out of date.

Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care [Internet].
Show detailsThis subject would benefit from further research in most areas. The guideline development group identified the following areas which they felt would help improve the evidence base for future versions of this guideline.
- Validation of risk assessment models is urgently needed.
- Different risk communication strategies should be evaluated.
- Prospective studies are needed of the short and long terms psychosocial and sexual impact of risk reducing surgery in women with a family history of breast cancer.
- Costs and benefits of surveillance in the 30–40 years age groups should be assessed by national pooling of all UK data.
- The effectiveness of surveillance, in particular mammography, in those aged 40–49 years.
- Endocrine prevention studies (tamoxifen, aromatase inhibitors) would be valuable.
- Relative effectiveness of different methods of gene mutation testing.
- The role and usefulness of computer packages in risk assessment, audit and other aspects of care would be useful.
- Research issues - Clinical Guidelines for the Classification and Care of Women a...Research issues - Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care
- Audit criteria - Clinical Guidelines for the Classification and Care of Women at...Audit criteria - Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care
- Risk factors - Clinical Guidelines for the Classification and Care of Women at R...Risk factors - Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care
- Care of women in specialist (secondary and tertiary) care - Clinical Guidelines ...Care of women in specialist (secondary and tertiary) care - Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care
- Care of women in primary care - Clinical Guidelines for the Classification and C...Care of women in primary care - Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care
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