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School of Health and Related Research (ScHARR), University of Sheffield. Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care [Internet]. Sheffield (UK): University of Sheffield; 2004 May. (NICE Clinical Guidelines, No. 14.)

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  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

Cover of Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care

Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care [Internet].

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Appendix 24Literature searches

Evidence pathway: to help identify areas for research literature searching (NB this is not a management/care algorithm – see Quick Reference Guide for management/care algorithms).

Evidence pathway: to help identify areas for research literature searching (NB this is not a management/care algorithm – see Quick Reference Guide for management/care algorithms)

Search strategies

Comprehensive searches were conducted in the major (11 in total) electronic bibliographic databases covering biomedical, nursing, psychological, social science and health economic literature. The searches were conducted from March 2002 until February 2003. In addition, the Web sites of several HTA and guideline producing bodies were consulted. Finally, the references lists of included articles were checked for additional references and citation searches were performed on key authors and papers in the Science and Social Science Citation Indexes.

Sources searched

Electronic databases

  1. CDSR (Cochrane Database of Systematic Reviews), The Cochrane Library, Issue 4, 2002
  2. CENTRAL/CCTR (Cochrane Central Register of Controlled Trials), The Cochrane Library, Issue 4, 2002
  3. Cinahl, 1982–2002
  4. Embase, 1980–2002
  5. Medline, 1966–2002
  6. NHS DARE (Database of Abstracts of Reviews of Effects), The Cochrane Library, Issue 4, 2002
  7. NHS HTA (Health Technology Assessment), The Cochrane Library, Issue 4, 2002
  8. PreMedline, August 2002
  9. PsycINFO, 1980–2002
  10. Science Citation Index, 1981–2002
  11. Social Science Citation Index, 1981–2002

Other sources

  1. National Guideline Clearinghouse
  2. NCCHTA (National Co-ordinating Centre for Health Technology Assessment)
  3. NICE (National Institute for Clinical Excellence)
  4. SIGN (Scottish Intercollegiate Guidelines Network)
  5. TRIP (Turning Research into Practice Database)

Search terms used in Medline (Ovid)

Breast cancer

  1. exp breast neoplasms/
  2. ((breast$ or mammar$) and (cancer$ or tumor$ or tumour$ or neoplasm$ or metasta$)).ti
  3. or/1–2
Familial breast cancer
  1. exp breast neoplasms/
  2. ((breast$ or mammar$) and (cancer$ or tumor$ or tumour$ or neoplasm$ or metasta$)).ti
  3. or/1–2
  4. exp genetics/
  5. exp genetic predisposition to disease/
  6. exp genetic techniques/
  7. brca1.tw
  8. brca2.tw
  9. high risk.ti
  10. familial.tw
  11. family histor$.ti
  12. hereditary.ti
  13. inherit$.ti
  14. genetic$.ti
  15. (gene or genes).ti
  16. exp breast neoplasms/ge
  17. or/1–16
Surgical interventions
  3. mammectom$.ti
  4. ovariectomy/
  5. oophorectom$.tw
  6. prophyl$ surg$.tw
  7. *surgery/
  8. exp breast neoplasm/su
  9. or/1–8
Tamoxifen
  1. tamoxifen.af
  2. nolvadex.af
  3. 10540-29-1.rn
  4. or/1–3
Risk modification factors
  1. exp diet/
  2. exp diet therapy/
  3. eating/
  4. exp body weight/
  5. diet$.ti
  6. food.ti
  7. weight.ti
  8. eat$.ti
  9. exercise/
  10. exercise therapy/
  11. exp exertion/
  12. physical fitness/
  13. exp sports/
  14. exercise$.ti
  15. fitness.ti
  16. sport$.ti
  17. menarche/
  18. menarche.ti
  19. alcohol drinking/
  20. alcohol.ti
  21. exp smoking/
  22. smok$.ti
  23. breast feeding/
  24. breast feed$.ti
  25. breastfeed$.ti
  26. breastfed.ti
  27. breast fed.ti
  28. exp family planning/
  29. exp contraception/
  30. family planning.ti
  31. contracept$.ti
  32. pill.ti
  33. birth control.ti
  34. exp reproductive techniques, assisted/
  35. in vitro fertil$.tw
  36. ivf.tw
  37. fertilization in vitro/
  39. hrt.tw
  40. ((hormone or oestrogen$ or estrogen$ or oestradiol or estradiol or progesteron$ or progestin) and replacement).ti
  41. exp self-examination/
  42. self-examin$.tw
  43. self-awar$.tw
  44. or/1–44
Breast/genetic screening
  1. exp mammography/
  2. mammography$.tw
  3. (breast$ and screen$).ti
  4. exp ultrasonography/
  5. ultraso$.ti
  7. magnetic resonance.ti
  8. ((non-invasive$ or non-invasive$) and (imag$ or diagnos$)).ti
  9. mri.ti
  10. mass screening/
  11. genetic screening/
  12. genetic test$.ti
  13. or/1–10
Genetic counselling/information/communication
  1. genetic counselling/
  2. (genetic$ and counsel$).ti
  3. *patient education/
  4. ((patient or health or genetic$) adj2 (educat$ or information)).ti
  5. leaflet$.ti
  6. video$.ti
  7. pamphlets/
  8. education$ material$.ti
  9. (communicat$ and risk$).ti
  10. or/1–9
  11. exp communication/
  12. exp risk
  13. 11 and 12
  14. 10 or 13
Risk classification
  1. risk assessment/
  2. (assess$ adj2 risk$).ti
  3. ((classif$ or category$ or stratify$) adj2 risk$).tw
  4. model$.ti
  5. *models, theoretical/
  6. exp * models, statistical/
  7. *models, genetic/
  8. risk$.ti
  9. gail model$.tw
  10. or/1–9
Family history taking
  1. exp medical history taking/
  2. (history$ adj2 tak$).tw
  3. or/1–2
Epidemiology
  1. exp epidemiology/
  2. incidence.ti
  3. prevalence.ti
  4. epidemiol$.ti
  5. or/1–4
Psychological impact/support & patient compliance
  1. psycho$.ti
  2. psychological support.tw
  3. counseling/
  4. exp *patient acceptance of health care/
  5. adaptation, psychological/
  6. patient compliance/
  7. patient satisfaction/
  8. *health status/
  9. *quality of life/
  10. or/1–9

a. Search approach

A staged approach to searching was undertaken. This involved initially searching specifically for the search concepts of interest (e.g. tamoxifen, surgical interventions, etc.) in conjunction with familial breast cancer search terms. Where this yielded, few or no relevant references, the search was expanded to cover high level evidence (i.e. guidelines, systematic reviews and randomised controlled trials) relating to breast cancer in general. Literature searches were also specifically undertaken in Medline, Embase, NHS EED and HEED, to specifically identify cost-effectiveness literature relating to familial breast cancer.

b. Search restrictions

No date restrictions were applied to the searches, other than those imposed by the sources searched. Searches were, however, restricted to English language. No study or publication type restrictions were applied, with the exception of the more general breast cancer searches which were restricted to the highest levels of evidence (i.e. guidelines, systematic reviews and randomised controlled trials). The corresponding methodological search filters used in Medline (Ovid) are given below.

c. Methodological search filters used in Medline (Ovid)

Guidelines

  1. guideline.pt
  2. practice guideline.pt
  3. exp guidelines/
  4. health planning guidelines/
  5. or/1–4

Systematic reviews

  1. meta-analysis/
  2. exp review literature/
  3. (meta-analy$ or meta analy$ or metaanaly$).tw
  4. meta analysis.pt
  5. review academic.pt
  6. review literature.pt
  7. (systematic$ adj3 (review$ or overview$)).tw
  8. letter.pt
  9. review of reported cases.pt
  10. historical article.pt
  11. review multicase.pt
  12. or/1–7
  13. or/8–11
  14. 12 not 13

Randomised controlled trials

  1. clinical trial.pt

Economic evaluations

  1. economics/
  2. exp “costs and cost analysis”/
  3. economic value of life/
  4. exp economics, hospital/
  5. exp economics, medical/
  6. economics, nursing/
  7. economics, pharmaceutical/
  8. exp models, economic/
  9. exp “fees and charges”/
  10. exp budgets/
  11. ec.fs
  12. cost$.ti
  13. economic$ or pharmacoeconomic$ or price$ or pricing.ti
  14. or/1–13

Quality of life

  1. exp quality of life/
  2. quality of life.tw
  3. life quality.tw
  4. hql.tw
  5. (sf 36 or sf36 or sf thirtysix or sf thirty six or short form 36 or short form thirty six or short form thirtysix or shortform 36).tw
  6. qol.tw
  7. (euroqol or eq5d or eq 5d).tw
  8. qaly$.tw
  9. quality adjusted life year$.tw
  10. hye$.tw
  11. health$ year$ equivalent$.tw
  12. health utilit$.tw
  13. hui.tw
  14. quality of wellbeing$.tw
  15. quality of well being.tw
  16. qwb.tw
  17. (qald$ or qale$ or qtime$).tw
  18. or/1–17
Copyright © 2004, School of Health and Related Research (ScHARR), University of Sheffield.
Bookshelf ID: NBK65451
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