- Discovery of ML370, an inhibitor of Vibrio cholerae Quorum Sensing Acting via the LuxO response regulator
- Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase
- ML368 Identification of Imidazopyridines as Selective Inhibitors of the Cytochrome P450 Enzyme CYP3A4
- Discovery of ML367, inhibitor of ATAD5 stabilization
- Discovery of ML366, an inhibitor of Vibrio cholerae Quorum Sensing Acting via the LuxO response regulator
- ML365: Development of Bis-Amides as Selective Inhibitors of the KCNK3/TASK1 Two Pore Potassium Channel
- ML360, A Potent Inhibitor of Lipid Droplet Formation
- Identification of ML359 as a Small Molecule Inhibitor of Protein Disulfide Isomerase
- A high throughput screen for inhibitors of nematode detoxification genes
- Selective inhibitors of FAS-TE
- Discovery of ML355, a Potent and Selective Inhibitor of Human 12-Lipoxygenase
- A Novel and Selective PAR4 Antagonist: ML354
- Identification of a high affinity MPEP-site silent allosteric modulator (SAM) for the metabotropic glutamate subtype 5 receptor (mGlu5)
- Discovery of ML351, a Potent and Selective Inhibitor of Human 15-Lipoxygenase-1
- Optimization and characterization of an opioid kappa receptor (OPRK1) antagonist
- Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2)
- Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 1 (LYPLA1)
- Development of a potent and ALK2 selective bone morphogenetic protein receptor (BMP) inhibitor
- ML346: A Novel Modulator of Proteostasis for Protein Conformational Diseases
- ML345, A Small-Molecule Inhibitor of the Insulin-Degrading Enzyme (IDE)
- Discovery of Two, Structurally Distinct Agonists of Vibrio cholerae Quorum Sensing Acting via the CqsS Membrane Receptor
- Inhibitors of FAP-fluorogen interaction as a multiplex assay tool compound for receptor internalization assays
- Identification of Diversity-Oriented Synthesis Derived Small Molecule, ML341, with Cidal Activity Against Trypanosoma cruzi
- Small-molecule antagonists of Gli function
- Probing the CXCR6/CXCL16 Axis: Targeting Prevention of Prostate Cancer Metastasis
- Elucidation of the physiology of non-replicating, drug tolerant Mycobacterium tuberculosis with the aid of the small molecule probe ML338
- Development of a Second Generation mGlu3 NAM Probe
- ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV)
- Characterization of an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerization
- The identification and characterization of non-reactive inhibitor of Keap1-Nrf2 interaction through HTS using a fluorescence polarization assay
- N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide inhibits E. coli UT189 bacterial capsule biogenesis
- Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5
- Cardioprotective inhibitors of reperfusion injury
- A Small Molecule Inhibitor of the MITF Molecular Pathway
- ML328: A Novel Dual Inhibitor of Bacterial AddAB and RecBCD Helicase-nuclease DNA Repair Enzymes
- Discovery of ML323 as a Novel Inhibitor of the USP1/UAF1 Deubiquitinase Complex
- Discovery and characterization of a small molecule that restores E-cadherin expression in cancer cell lines via a new mechanism
- Development and characterization of a highly selective M5 PAM probe molecule with improved potency
- Optimization and characterization of a pan protein arginine deiminase (PAD) inhibitor
- Discovery of ML324, a JMJD2 demethylase inhibitor with demonstrated antiviral activity
- ML322, A Small Molecule Inhibitor of Dimerization of the Core Protein of Hepatitis C Virus (HCV)
- Discovery, optimization, and characterization of a novel series of dopamine D2 versus D3 receptor selective antagonists
Publication Details
Copyright
Publisher
National Center for Biotechnology Information (US), Bethesda (MD)
NLM Citation
Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-. Year 5 Reports.