NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
- Discovery of ML370, an inhibitor of Vibrio cholerae Quorum Sensing Acting via the LuxO response regulator
- Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase
- ML368 Identification of Imidazopyridines as Selective Inhibitors of the Cytochrome P450 Enzyme CYP3A4
- Discovery of ML367, inhibitor of ATAD5 stabilization
- Discovery of ML366, an inhibitor of Vibrio cholerae Quorum Sensing Acting via the LuxO response regulator
- ML365: Development of Bis-Amides as Selective Inhibitors of the KCNK3/TASK1 Two Pore Potassium Channel
- ML360, A Potent Inhibitor of Lipid Droplet Formation
- Identification of ML359 as a Small Molecule Inhibitor of Protein Disulfide Isomerase
- A high throughput screen for inhibitors of nematode detoxification genes
- Selective inhibitors of FAS-TE
- Discovery of ML355, a Potent and Selective Inhibitor of Human 12-Lipoxygenase
- A Novel and Selective PAR4 Antagonist: ML354
- Identification of a high affinity MPEP-site silent allosteric modulator (SAM) for the metabotropic glutamate subtype 5 receptor (mGlu5)
- Discovery of ML351, a Potent and Selective Inhibitor of Human 15-Lipoxygenase-1
- Optimization and characterization of an opioid kappa receptor (OPRK1) antagonist
- Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2)
- Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 1 (LYPLA1)
- Development of a potent and ALK2 selective bone morphogenetic protein receptor (BMP) inhibitor
- ML346: A Novel Modulator of Proteostasis for Protein Conformational Diseases
- ML345, A Small-Molecule Inhibitor of the Insulin-Degrading Enzyme (IDE)
- Discovery of Two, Structurally Distinct Agonists of Vibrio cholerae Quorum Sensing Acting via the CqsS Membrane Receptor
- Inhibitors of FAP-fluorogen interaction as a multiplex assay tool compound for receptor internalization assays
- Identification of Diversity-Oriented Synthesis Derived Small Molecule, ML341, with Cidal Activity Against Trypanosoma cruzi
- Small-molecule antagonists of Gli function
- Probing the CXCR6/CXCL16 Axis: Targeting Prevention of Prostate Cancer Metastasis
- Elucidation of the physiology of non-replicating, drug tolerant Mycobacterium tuberculosis with the aid of the small molecule probe ML338
- Development of a Second Generation mGlu3 NAM Probe
- ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV)
- Characterization of an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerization
- The identification and characterization of non-reactive inhibitor of Keap1-Nrf2 interaction through HTS using a fluorescence polarization assay
- N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide inhibits E. coli UT189 bacterial capsule biogenesis
- Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5
- Cardioprotective inhibitors of reperfusion injury
- A Small Molecule Inhibitor of the MITF Molecular Pathway
- ML328: A Novel Dual Inhibitor of Bacterial AddAB and RecBCD Helicase-nuclease DNA Repair Enzymes
- Discovery of ML323 as a Novel Inhibitor of the USP1/UAF1 Deubiquitinase Complex
- Discovery and characterization of a small molecule that restores E-cadherin expression in cancer cell lines via a new mechanism
- Development and characterization of a highly selective M5 PAM probe molecule with improved potency
- Optimization and characterization of a pan protein arginine deiminase (PAD) inhibitor
- Discovery of ML324, a JMJD2 demethylase inhibitor with demonstrated antiviral activity
- ML322, A Small Molecule Inhibitor of Dimerization of the Core Protein of Hepatitis C Virus (HCV)
- Discovery, optimization, and characterization of a novel series of dopamine D2 versus D3 receptor selective antagonists
- Year 5 Reports - Probe Reports from the NIH Molecular Libraries ProgramYear 5 Reports - Probe Reports from the NIH Molecular Libraries Program
- Identification of a chemically validated target in replicating and non-replicati...Identification of a chemically validated target in replicating and non-replicating Mycobacterium tuberculosis with the aid of a small molecule probe - Probe Reports from the NIH Molecular Libraries Program
- Discovery and Evaluation of Fungicidal Anti-Cryptococcal Molecules - Probe Repor...Discovery and Evaluation of Fungicidal Anti-Cryptococcal Molecules - Probe Reports from the NIH Molecular Libraries Program
- Discovery of small molecule probe that shows anti-tubercular activity via Mtb bi...Discovery of small molecule probe that shows anti-tubercular activity via Mtb bioA (DAPA synthase) enzyme inhibition - Probe Reports from the NIH Molecular Libraries Program
- Small Molecules Targeting the Mitochondrial Permeability Transition - Probe Repo...Small Molecules Targeting the Mitochondrial Permeability Transition - Probe Reports from the NIH Molecular Libraries Program
Your browsing activity is empty.
Activity recording is turned off.
See more...