| Outcomes | No of Participants (studies) Follow up | Quality of the evidence (GRADE) | Relative effect (95% CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
| Risk with Control | Risk difference with Treatment versus no treatment (95% CI) | ||||
| Stroke <80 mmHg |
42,599 (1 study) 4 years |
due to indirectness, imprecision |
RR 0.74 (0.68 to 0.82) | 45 per 1,000 | 12 fewer per 1,000 (from 8 fewer to 15 fewer) |
| Stroke 80–84 mmHg |
37,516 (1 study) 4 years |
due to indirectness, imprecision |
RR 0.76 (0.67 to 0.87) | 28 per 1,000 | 7 fewer per 1,000 (from 4 fewer to 9 fewer) |
| Stroke 85–89 mmHg |
39,731 (1 study) 4 years |
LOW1 due to indirectness |
RR 0.68 (0.62 to 0.75) | 45 per 1,000 | 14 fewer per 1,000 (from 11 fewer to 17 fewer) |
| Stroke 90–94 mmHg |
38,646 (1 study) 4 years |
LOW1 due to indirectness |
RR 0.63 (0.56 to 0.71) | 33 per 1,000 | 12 fewer per 1,000 (from 9 fewer to 14 fewer) |
| Stroke >95 mmHg |
6,195 (1 study) 4 years |
LOW1 due to indirectness |
RR 0.51 (0.41 to 0.63) | 73 per 1,000 | 36 fewer per 1,000 (from 27 fewer to 43 fewer) |
Downgraded by 1 or 2 increments due to population or outcome indirectness
Downgraded by 1 increment if the confidence interval crossed 1 MID or by 2 increments if the confidence interval crossed both MIDs.
From: Evidence review for initiating treatment
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