| 1. | exp Hypertension/ |
| 2. | hypertens*.ti,ab. |
| 3. | (elevat* adj2 blood adj pressur*).ti,ab. |
| 4. | (high adj blood adj pressur*).ti,ab. |
| 5. | (increase* adj2 blood pressur*).ti,ab. |
| 6. | ((systolic or diastolic or arterial) adj2 pressur*).ti,ab. |
| 7. | or/1–6 |
| 8. | letter/ |
| 9. | editorial/ |
| 10. | news/ |
| 11. | exp historical article/ |
| 12. | Anecdotes as Topic/ |
| 13. | comment/ |
| 14. | case report/ |
| 15. | (letter or comment*).ti. |
| 16. | or/8–15 |
| 17. | randomized controlled trial/ or random*.ti,ab. |
| 18. | 16 not 17 |
| 19. | animals/ not humans/ |
| 20. | exp Animals, Laboratory/ |
| 21. | exp Animal Experimentation/ |
| 22. | exp Models, Animal/ |
| 23. | exp Rodentia/ |
| 24. | (rat or rats or mouse or mice).ti. |
| 25. | or/18–24 |
| 26. | 7 not 25 |
| 27. | limit 26 to English language |
| 28. | Economics/ |
| 29. | Value of life/ |
| 30. | exp “Costs and Cost Analysis”/ |
| 31. | exp Economics, Hospital/ |
| 32. | exp Economics, Medical/ |
| 33. | Economics, Nursing/ |
| 34. | Economics, Pharmaceutical/ |
| 35. | exp “Fees and Charges”/ |
| 36. | exp Budgets/ |
| 37. | budget*.ti,ab. |
| 38. | cost*.ti. |
| 39. | (economic* or pharmaco?economic*).ti. |
| 40. | (price* or pricing*).ti,ab. |
| 41. | (cost* adj2 (effective* or utilit* or benefit* or minimi* or unit* or estimat* or variable*)).ab. |
| 42. | (financ* or fee or fees).ti,ab. |
| 43. | (value adj2 (money or monetary)).ti,ab. |
| 44. | or/28–43 |
| 45. | 27 and 44 |
From: Evidence review for initiating treatment
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