Risk factors

Contents

• 1. Prognostic factors for poor function
  • 1.1. Review question: In adults with rheumatoid arthritis, which risk factors are associated with poorer long-term function as measured by the Health Assessment Questionnaire (HAQ)?
  • 1.2. Introduction
  • 1.3. PICO table
  • 1.4. Methods and process
  • 1.5. Clinical evidence
  • 1.6. Economic evidence
  • 1.7. Resource costs
  • 1.8. Evidence statements
• 2. Prognostic factors for radiographic progression
  • 2.1. Review question: In adults with rheumatoid arthritis, which risk factors are associated with worse radiographic progression?
  • 2.2. Introduction
  • 2.3. PICO table
  • 2.4. Methods and process
  • 2.5. Clinical evidence
  • 2.6. Economic evidence
  • 2.7. Resource costs
  • 2.8. Evidence statements
  • 2.9. The committee’s discussion of the evidence
• References
• Appendices
  • Appendix A. Review protocols
  • Appendix B. Literature search strategies
  • Appendix C. Clinical evidence selection
  • Appendix D. Clinical evidence tables
  • Appendix E. Forest plots
  • Appendix F. GRADE tables
  • Appendix G. Health economic evidence selection
  • Appendix H. Health economic evidence tables
  • Appendix I. Excluded studies
  • Appendix J. Research recommendations

Final

Prognostic evidence review

Developed by the National Guideline Centre, hosted by the Royal College of Physicians

The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or service users. The recommendations in this guideline are not mandatory and the guideline does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and, where appropriate, their carer or guardian.

Local commissioners and providers have a responsibility to enable the guideline to be applied when individual health professionals and their patients or service users wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties.

NICE guidelines cover health and care in England. Decisions on how they apply in other UK countries are made by ministers in the Welsh Government, Scottish Government, and Northern Ireland Executive. All NICE guidance is subject to regular review and may be updated or withdrawn.