CASRN: 8050-81-5
Drug Levels and Effects
Summary of Use during Lactation
Although no data are available on the use of simethicone during breastfeeding, it is known that simethicone is not absorbed orally. Therefore, it cannot be transferred to breastmilk. It is also used safely in breastfed infants.[1,2] No special precautions are required.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998;14:259–62. [PubMed: 10205441]
- 2.
- Savino F, Pelle E, Palumeri E, et al. Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: A prospective randomized study. Pediatrics. 2007;119:e124–30. [PubMed: 17200238]
Substance Identification
Substance Name
Simethicone
CAS Registry Number
8050-81-5
Drug Class
Breast Feeding
Lactation
Antifoaming Agents
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Publication Details
Publication History
Last Revision: March 17, 2021.
Copyright
Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Publisher
National Institute of Child Health and Human Development, Bethesda (MD)
NLM Citation
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Simethicone. [Updated 2021 Mar 17].