9MJ5: Catalytic domain of human DNA polymerase alpha in complex with DNA and RPA

PDB ID: 9MJ5Download
MMDB ID: 259627
PDB Deposition Date: 2024/12/13
Updated in MMDB: 2025/03
Experimental Method:
electron microscopy
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 9MJ5: hexameric; determined by author and by software
Molecular Components in 9MJ5
Label Count Molecule
Proteins (4 molecules)
1
Replication Protein a 14 KDA Subunit
Molecule annotation
1
Replication Protein a 32 KDA Subunit
Molecule annotation
1
Replication Protein a 70 KDA DNA-binding Subunit
Molecule annotation
1
DNA Polymerase Alpha Catalytic Subunit
Molecule annotation
Nucleotide(1 molecule)
1
DNA Template (35-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
P
1
RNA-DNA primer (11-mer)
1
1
ZINC ION (Link to PubChem not yet available)ZINC ION
2
1
MAGNESIUM ION (Link to PubChem not yet available)MAGNESIUM ION
3
1
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE (Link to PubChem not yet available)2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303