9F2W: Cryo-EM structure of the I923V MDA5-dsRNA filament in complex with ATP

PDB ID: 9F2WDownload
MMDB ID: 260039
PDB Deposition Date: 2024
Updated in MMDB: 2025/03
Experimental Method:
electron microscopy
Resolution: 4.21  Å
Source Organism:
Similar Structures:
Biological Unit for 9F2W: hexameric; determined by author and by software
Molecular Components in 9F2W
Label Count Molecule
Proteins (2 molecules)
2
Interferon-induced Helicase C Domain-containing Protein 1
Molecule annotation
Nucleotides(4 molecules)
2
RNA (5'-r(p*cp*ap*ap*gp*cp*cp*gp*ap*gp*gp*ap*gp*ap*u)-3')
Molecule annotation
2
RNA (5'-r(p*ap*up*cp*up*cp*cp*up*cp*gp*gp*cp*up*up*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
ZINC IONZINC ION
2
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303