7SX7: Crystal structure of broadly neutralizing antibody N49P9.3-FR3-3 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core

PDB ID: 7SX7Download
MMDB ID: 259084
PDB Deposition Date: 2021/11/22
Updated in MMDB: 2025/02
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Human immunodeficiency virus 1▼
Similar Structures:
Biological Unit for 7SX7: trimeric; determined by author and by software (PISA)
Molecular Components in 7SX7
Label Count Molecule
Proteins (3 molecules)
1
Clade A/E 93th057 Hiv-1 Gp120 Core
Molecule annotation
1
N49p9.3-fr3-3 Antibody FAB Heavy Chain
Molecule annotation
1
N49p9.3-fr3-3 Antibody FAB Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
11
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303