7K0U: Crystal structure of the second bromodomain (BD2) of human TAF1 bound to PLK1 kinase inhibitor BI2536

PDB ID: 7K0UDownload
MMDB ID: 206742
PDB Deposition Date: 2020/9/6
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.52  Å
Source Organism:
Similar Structures:
Biological Unit for 7K0U: dimeric; determined by author
Molecular Components in 7K0U
Label Count Molecule
Proteins (2 molecules)
2
Transcription Initiation Factor Tfiid Subunit 1
(Gene symbol: TAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303