Isavuconazole
- PMID: 38652797
- Bookshelf ID: NBK603031
Isavuconazole
Excerpt
No information is available on the clinical use of isavuconazole during breastfeeding. Because isavuconazole is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, there is no published experience with isavuconazole during breastfeeding, so an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Similar articles
-
Two Phase 1, Open-Label, Mass Balance Studies to Determine the Pharmacokinetics of 14 C-Labeled Isavuconazonium Sulfate in Healthy Male Volunteers.Clin Pharmacol Drug Dev. 2018 Feb;7(2):207-216. doi: 10.1002/cpdd.376. Epub 2017 Jul 27. Clin Pharmacol Drug Dev. 2018. PMID: 28750160 Free PMC article. Clinical Trial.
-
Isavuconazole absorption following oral administration in healthy subjects is comparable to intravenous dosing, and is not affected by food, or drugs that alter stomach pH.Int J Clin Pharmacol Ther. 2016 Aug;54(8):572-80. doi: 10.5414/CP202434. Int J Clin Pharmacol Ther. 2016. PMID: 27345284 Clinical Trial.
-
Direct in vitro comparison of the prodrug isavuconazonium sulfate with the isavuconazole active compound against Aspergillus spp. and 2 rare moulds.Diagn Microbiol Infect Dis. 2018 Sep;92(1):43-45. doi: 10.1016/j.diagmicrobio.2018.04.005. Epub 2018 Apr 13. Diagn Microbiol Infect Dis. 2018. PMID: 29735424
-
Isavuconazole: A Review in Invasive Aspergillosis and Mucormycosis.Drugs. 2016 Nov;76(17):1647-1657. doi: 10.1007/s40265-016-0652-6. Drugs. 2016. PMID: 27766566 Review.
-
Avacopan.2023 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 38051796 Free Books & Documents. Review.
Publication types
LinkOut - more resources
Full Text Sources
Research Materials