Recommendations from the Pediatric Endocrine Society for Evaluation and Management of Persistent Hypoglycemia in Neonates, Infants, and Children

doi:10.1016/j.jpeds.2015.03.057

Practice Guideline

. 2015 Aug;167(2):238-45.

doi: 10.1016/j.jpeds.2015.03.057. Epub 2015 May 6.

Recommendations from the Pediatric Endocrine Society for Evaluation and Management of Persistent Hypoglycemia in Neonates, Infants, and Children

Affiliations

¹ Division of Endocrinology, Cook Children's Medical Center, Fort Worth, TX. Electronic address: Paul.thornton@cookchildrens.org.
² Division of Endocrinology, The Children's Hospital of Philadelphia, Philadelphia, PA.
³ Newborn Intensive Care Unit, Waikato District Health Board, Hamilton, New Zealand.
⁴ Children's Nutrition Research Center, Texas Children's Hospital, Houston, TX.
⁵ Department of Endocrinology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
⁶ Pediatric Endocrine Unit, Massachusetts General Hospital, Boston, MA.
⁷ Division of Preventive Medicine, Mayo Clinic, Rochester, MN.
⁸ Division of Neonatology, University of Colorado School of Medicine, Aurora, CO.
⁹ Division of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA.
¹⁰ Division of Endocrinology, Diabetes and Metabolism, Children's Hospital of Pittsburgh, Pittsburgh, PA.
¹¹ Glycogen Storage Disease Program, University of Florida College of Medicine, Gainesville, FL.
¹² Department of Pediatrics and Medicine, Washington University in St Louis, St Louis, MO.
¹³ Division of Endocrinology, Boston Children's Hospital, Boston, MA.

PMID: 25957977
PMCID: PMC11891912
DOI: 10.1016/j.jpeds.2015.03.057

Practice Guideline

Recommendations from the Pediatric Endocrine Society for Evaluation and Management of Persistent Hypoglycemia in Neonates, Infants, and Children

Paul S Thornton et al. J Pediatr. 2015 Aug.

. 2015 Aug;167(2):238-45.

doi: 10.1016/j.jpeds.2015.03.057. Epub 2015 May 6.

Authors

Affiliations

¹ Division of Endocrinology, Cook Children's Medical Center, Fort Worth, TX. Electronic address: Paul.thornton@cookchildrens.org.
² Division of Endocrinology, The Children's Hospital of Philadelphia, Philadelphia, PA.
³ Newborn Intensive Care Unit, Waikato District Health Board, Hamilton, New Zealand.
⁴ Children's Nutrition Research Center, Texas Children's Hospital, Houston, TX.
⁵ Department of Endocrinology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
⁶ Pediatric Endocrine Unit, Massachusetts General Hospital, Boston, MA.
⁷ Division of Preventive Medicine, Mayo Clinic, Rochester, MN.
⁸ Division of Neonatology, University of Colorado School of Medicine, Aurora, CO.
⁹ Division of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA.
¹⁰ Division of Endocrinology, Diabetes and Metabolism, Children's Hospital of Pittsburgh, Pittsburgh, PA.
¹¹ Glycogen Storage Disease Program, University of Florida College of Medicine, Gainesville, FL.
¹² Department of Pediatrics and Medicine, Washington University in St Louis, St Louis, MO.
¹³ Division of Endocrinology, Boston Children's Hospital, Boston, MA.

PMID: 25957977
PMCID: PMC11891912
DOI: 10.1016/j.jpeds.2015.03.057

No abstract available

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Conflict of interest statement

The authors declare no conflicts of interest.

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Higher C-peptide levels and glucose requirements may identify neonates with transient hyperinsulinism hypoglycemia who will benefit from diazoxide treatment.
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References

1. Cornblath M, Reisner SH. Blood glucose in the neonate and its clinical significance. N Engl J Med 1965;273:378–81. - PubMed
1. Srinivasan G, Pildes RS, Cattamanchi G, Voora S, Lilien LD. Plasma glucose values in normal neonates: a new look. J Pediatr 1986;109:114–7. - PubMed
1. Stanley CA, Rozance PJ, Thornton PS, De Leon DD, Harris D, Haymond MW, et al. Re-evaluating “transitional neonatal hypoglycemia”: mechanism and implications for management. J Pediatr 2015;166:1520–5. - PMC - PubMed
1. Canadian Paediatric Society. Screening guidelines for newborns at risk for low blood glucose. Paediatr Child Health 2004;9:723–40. - PMC - PubMed
1. Adamkin DH. Postnatal glucose homeostasis in late-preterm and term infants. Pediatrics 2011;127:575–9. - PubMed

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[1] Cornblath M, Reisner SH. Blood glucose in the neonate and its clinical significance. N Engl J Med 1965;273:378–81. - PubMed

[2] Cornblath M, Reisner SH. Blood glucose in the neonate and its clinical significance. N Engl J Med 1965;273:378–81. - PubMed

[3] Srinivasan G, Pildes RS, Cattamanchi G, Voora S, Lilien LD. Plasma glucose values in normal neonates: a new look. J Pediatr 1986;109:114–7. - PubMed

[4] Srinivasan G, Pildes RS, Cattamanchi G, Voora S, Lilien LD. Plasma glucose values in normal neonates: a new look. J Pediatr 1986;109:114–7. - PubMed

[5] Stanley CA, Rozance PJ, Thornton PS, De Leon DD, Harris D, Haymond MW, et al. Re-evaluating “transitional neonatal hypoglycemia”: mechanism and implications for management. J Pediatr 2015;166:1520–5. - PMC - PubMed

[6] Stanley CA, Rozance PJ, Thornton PS, De Leon DD, Harris D, Haymond MW, et al. Re-evaluating “transitional neonatal hypoglycemia”: mechanism and implications for management. J Pediatr 2015;166:1520–5. - PMC - PubMed

[7] Canadian Paediatric Society. Screening guidelines for newborns at risk for low blood glucose. Paediatr Child Health 2004;9:723–40. - PMC - PubMed

[8] Canadian Paediatric Society. Screening guidelines for newborns at risk for low blood glucose. Paediatr Child Health 2004;9:723–40. - PMC - PubMed

[9] Adamkin DH. Postnatal glucose homeostasis in late-preterm and term infants. Pediatrics 2011;127:575–9. - PubMed

[10] Adamkin DH. Postnatal glucose homeostasis in late-preterm and term infants. Pediatrics 2011;127:575–9. - PubMed

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Recommendations from the Pediatric Endocrine Society for Evaluation and Management of Persistent Hypoglycemia in Neonates, Infants, and Children

Affiliations

Recommendations from the Pediatric Endocrine Society for Evaluation and Management of Persistent Hypoglycemia in Neonates, Infants, and Children

Authors

Affiliations

Conflict of interest statement

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Conflict of interest statement

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