Dilated Cardiomyopathy Overview
- PMID: 20301486
- Bookshelf ID: NBK1309
Dilated Cardiomyopathy Overview
Excerpt
The purpose of this overview is to:
- 1
Define DCM;
- 2
Identify the categories of DCM;
- 3
Provide the evaluation strategy of a proband with nonsyndromic DCM;
- 4
Provide a basic view of genetic risk assessment of at-risk asymptomatic relatives of a proband with DCM to inform cardiac surveillance and allow early detection and treatment of DCM to improve long-term outcome.
Copyright © 1993-2025, University of Washington, Seattle. GeneReviews is a registered trademark of the University of Washington, Seattle. All rights reserved.
Sections
- Summary
- 1. Dilated Cardiomyopathy (DCM): Definition
- 2. Dilated Cardiomyopathy (DCM): Categories
- 3. Establishing (When Possible) the Specific Genetic Cause of DCM
- 4. Genetic Risk Assessment and Cardiac Surveillance of At-Risk Relatives for Detection of Early Treatable Manifestations of DCM
- Resources
- Chapter Notes
- References
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References
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- Alkhunaizi E, Martin N, Jelin AC, Rosner M, Bailey DJ, Steiner LA, Lakhani S, Ji W, Katzman PJ, Forster KR, Jarinova O, Shannon P, Chitayat D; Care4Rare Canada Consortium. Fetal akinesia deformation sequence syndrome associated with recessive TTN variants. Am J Med Genet A. 2023;191:760-9. - PMC - PubMed
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- Burkett EL, Hershberger RE. Clinical and genetic issues in familial dilated cardiomyopathy. J Am Coll Cardiol. 2005;45:969-81. - PubMed
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- Caleshu C, Day S, Rehm HL, Baxter S. Use and interpretation of genetic tests in cardiovascular genetics. Heart. 2010;96:1669-75. - PubMed
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