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. 2003 Jan;48(1):227-30.
doi: 10.1002/art.10755.

Arthropathy in juvenile hemochromatosis

George Vaiopoulos  1 , George Papanikolaou, Marianna Politou, Iyad Jibreel, Nikos Sakellaropoulos, Dimitris Loukopoulos
Affiliations
Free article

Arthropathy in juvenile hemochromatosis

George Vaiopoulos et al. Arthritis Rheum. 2003 Jan.
Free article

Abstract

Objective: To evaluate whether arthropathy is associated with juvenile hemochromatosis and, if so, to assess the relationship between this feature and other clinical features of the disease.

Methods: Clinical, laboratory, and radiologic evidence of arthropathy was studied in 8 Greek patients with genetically proven juvenile hemochromatosis. Osteopenia and osteoporosis were assessed by bone mineral density measurement.

Results: Seven of the 8 patients had articular manifestations. The main affected joint was the metacarpophalangeal joint, and the arthritis was progressive independent of phlebotomy therapy. Osteopenia was observed in 2 patients, and osteoporosis in 2 patients.

Conclusion: Arthropathy may be present in patients with juvenile hemochromatosis, with features similar to those found in patients with hemochromatosis type 1.

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