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. 2000 Nov;15(6):1242-7.
doi: 10.1002/1531-8257(200011)15:6<1242::aid-mds1028>3.0.co;2-z.

Intrathecal baclofen for dystonia: benefits and complications during six years of experience

R H Walker  1 , F O Danisi, D M Swope, R R Goodman, I M Germano, M F Brin
Affiliations

Intrathecal baclofen for dystonia: benefits and complications during six years of experience

R H Walker et al. Mov Disord. 2000 Nov.

Abstract

Fourteen patients with primary or secondary dystonia received intrathecal baclofen (ITB) through an implanted pump following a trial dose. Patients were selected for ITB trial if they had clinically unsatisfactory responses to oral antidystonic medications, including oral baclofen. Patients were rated using the Burke-Fahn-Marsden rating scale by a blinded rater after the dose of ITB was optimized. Five patients experienced improvement in symptoms as determined by a change in rating scale scores, although only two had a clear clinical benefit. Etiology of dystonia did not determine the efficacy of ITB therapy, as benefit or failure was seen in both primary and secondary dystonia.

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  • Intrathecal baclofen for dystonia.
    Hou JG, Ondo W, Jankovic J. Hou JG, et al. Mov Disord. 2001 Nov;16(6):1201-2. doi: 10.1002/mds.1215. Mov Disord. 2001. PMID: 11748766 No abstract available.

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