Name: rs1801159
Published: September 3, 2024
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs1801159

Current Build 157

Released September 3, 2024

Organism: Homo sapiens
Position: chr1:97515839 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: T>A / T>C / T>G
Variation Type: SNV Single Nucleotide Variation
Frequency: C=0.1957528 (274151/1400496, GnomAD_exomes)
C=0.198452 (73496/370346, ALFA)
C=0.194975 (51608/264690, TOPMED) (+ 27 more)
C=0.186399 (27753/148890, GnomAD_genomes)
C=0.192959 (23296/120730, ExAC)
C=0.21430 (16866/78702, PAGE_STUDY)
C=0.28159 (21734/77182, 38KJPN)
C=0.18361 (2388/13006, GO-ESP)
C=0.2553 (1846/7232, Korea4K)
C=0.1838 (1177/6404, 1000G_30X)
C=0.1849 (926/5008, 1000G)
C=0.1408 (631/4480, Estonian)
C=0.2039 (786/3854, ALSPAC)
C=0.2023 (750/3708, TWINSUK)
C=0.3271 (1073/3280, PRJNA289433)
C=0.2696 (790/2930, KOREAN)
C=0.1946 (367/1886, HapMap)
C=0.2636 (483/1832, Korea1K)
C=0.1836 (206/1122, Daghestan)
C=0.217 (217/998, GoNL)
C=0.258 (197/764, PRJEB37584)
C=0.174 (128/734, PharmGKB)
C=0.223 (137/614, Vietnamese)
C=0.180 (108/600, NorthernSweden)
C=0.206 (110/534, MGP)
C=0.141 (43/304, FINRISK)
T=0.417 (100/240, SGDP_PRJ)
C=0.204 (44/216, Qatari)
C=0.10 (4/40, GENOME_DK)
T=0.46 (11/24, Siberian)

Clinical Significance: Reported in ClinVar
Gene : Consequence: DPYD : Missense Variant
Publications: 26 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315

Population	Group	Sample Size	Ref Allele	Alt Allele	Ref HMOZ	Alt HMOZ	HTRZ	HWEP
Total	Global	370346	T=0.801548	C=0.198452	0.643523	0.040427	0.31605	5
European	Sub	309490	T=0.801438	C=0.198562	0.642573	0.039698	0.317729	0
African	Sub	16492	T=0.84720	C=0.15280	0.71853	0.024133	0.257337	0
African Others	Sub	592	T=0.861	C=0.139	0.743243	0.02027	0.236486	0
African American	Sub	15900	T=0.84667	C=0.15333	0.71761	0.024277	0.258113	0
Asian	Sub	6928	T=0.7435	C=0.2565	0.560624	0.073614	0.365762	4
East Asian	Sub	4960	T=0.7421	C=0.2579	0.559274	0.075	0.365726	3
Other Asian	Sub	1968	T=0.7470	C=0.2530	0.564024	0.070122	0.365854	1
Latin American 1	Sub	1488	T=0.8394	C=0.1606	0.705645	0.026882	0.267473	0
Latin American 2	Sub	7228	T=0.6995	C=0.3005	0.486718	0.087714	0.425567	0
South Asian	Sub	5224	T=0.9154	C=0.0846	0.843415	0.012634	0.143951	8
Other	Sub	23496	T=0.79175	C=0.20825	0.627681	0.044178	0.328141	0

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
gnomAD v4 - Exomes	Global	Study-wide	1400496	T=0.8042472	C=0.1957528
gnomAD v4 - Exomes	European	Sub	1164690	T=0.8017335	C=0.1982665
gnomAD v4 - Exomes	South Asian	Sub	86240	T=0.90435	C=0.09565
gnomAD v4 - Exomes	American	Sub	44600	T=0.70608	C=0.29392
gnomAD v4 - Exomes	East Asian	Sub	39684	T=0.72873	C=0.27127
gnomAD v4 - Exomes	African	Sub	33432	T=0.84566	C=0.15434
gnomAD v4 - Exomes	Ashkenazi Jewish	Sub	26088	T=0.80512	C=0.19488
gnomAD v4 - Exomes	Middle Eastern	sub	5762	T=0.8499	C=0.1501
Allele Frequency Aggregator	Total	Global	370346	T=0.801548	C=0.198452
Allele Frequency Aggregator	European	Sub	309490	T=0.801438	C=0.198562
Allele Frequency Aggregator	Other	Sub	23496	T=0.79175	C=0.20825
Allele Frequency Aggregator	African	Sub	16492	T=0.84720	C=0.15280
Allele Frequency Aggregator	Latin American 2	Sub	7228	T=0.6995	C=0.3005
Allele Frequency Aggregator	Asian	Sub	6928	T=0.7435	C=0.2565
Allele Frequency Aggregator	South Asian	Sub	5224	T=0.9154	C=0.0846
Allele Frequency Aggregator	Latin American 1	Sub	1488	T=0.8394	C=0.1606
TopMed	Global	Study-wide	264690	T=0.805025	C=0.194975
gnomAD v4 - Genomes	Global	Study-wide	148890	T=0.813601	C=0.186399
gnomAD v4 - Genomes	European	Sub	78480	T=0.80796	C=0.19204
gnomAD v4 - Genomes	African	Sub	41482	T=0.84130	C=0.15870
gnomAD v4 - Genomes	American	Sub	15214	T=0.76272	C=0.23728
gnomAD v4 - Genomes	East Asian	Sub	5132	T=0.7451	C=0.2549
gnomAD v4 - Genomes	South Asian	Sub	4826	T=0.9036	C=0.0964
gnomAD v4 - Genomes	Ashkenazi Jewish	Sub	3464	T=0.8057	C=0.1943
gnomAD v4 - Genomes	Middle Eastern	sub	292	T=0.853	C=0.147
ExAC	Global	Study-wide	120730	T=0.807041	C=0.192959
ExAC	Europe	Sub	72982	T=0.80510	C=0.19490
ExAC	Asian	Sub	25090	T=0.85130	C=0.14870
ExAC	American	Sub	11378	T=0.68843	C=0.31157
ExAC	African	Sub	10376	T=0.84262	C=0.15738
ExAC	Other	Sub	904	T=0.820	C=0.180
The PAGE Study	Global	Study-wide	78702	T=0.78570	C=0.21430
The PAGE Study	AfricanAmerican	Sub	32516	T=0.83873	C=0.16127
The PAGE Study	Mexican	Sub	10810	T=0.72081	C=0.27919
The PAGE Study	Asian	Sub	8318	T=0.7085	C=0.2915
The PAGE Study	PuertoRican	Sub	7918	T=0.7815	C=0.2185
The PAGE Study	NativeHawaiian	Sub	4534	T=0.7360	C=0.2640
The PAGE Study	Cuban	Sub	4230	T=0.7920	C=0.2080
The PAGE Study	Dominican	Sub	3828	T=0.8192	C=0.1808
The PAGE Study	CentralAmerican	Sub	2450	T=0.7233	C=0.2767
The PAGE Study	SouthAmerican	Sub	1982	T=0.6963	C=0.3037
The PAGE Study	NativeAmerican	Sub	1260	T=0.7444	C=0.2556
The PAGE Study	SouthAsian	Sub	856	T=0.909	C=0.091
38KJPN	JAPANESE	Study-wide	77182	T=0.71841	C=0.28159
GO Exome Sequencing Project	Global	Study-wide	13006	T=0.81639	C=0.18361
GO Exome Sequencing Project	European American	Sub	8600	T=0.8019	C=0.1981
GO Exome Sequencing Project	African American	Sub	4406	T=0.8448	C=0.1552
Korean Genome Project 4K	KOREAN	Study-wide	7232	T=0.7447	C=0.2553
1000Genomes_30X	Global	Study-wide	6404	T=0.8162	C=0.1838
1000Genomes_30X	African	Sub	1786	T=0.8533	C=0.1467
1000Genomes_30X	Europe	Sub	1266	T=0.8128	C=0.1872
1000Genomes_30X	South Asian	Sub	1202	T=0.9176	C=0.0824
1000Genomes_30X	East Asian	Sub	1170	T=0.7342	C=0.2658
1000Genomes_30X	American	Sub	980	T=0.727	C=0.273
1000Genomes	Global	Study-wide	5008	T=0.8151	C=0.1849
1000Genomes	African	Sub	1322	T=0.8464	C=0.1536
1000Genomes	East Asian	Sub	1008	T=0.7341	C=0.2659
1000Genomes	Europe	Sub	1006	T=0.8121	C=0.1879
1000Genomes	South Asian	Sub	978	T=0.917	C=0.083
1000Genomes	American	Sub	694	T=0.733	C=0.267
Genetic variation in the Estonian population	Estonian	Study-wide	4480	T=0.8592	C=0.1408
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.7961	C=0.2039
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.7977	C=0.2023
MxGDAR/Encodat-PGx	Global	Study-wide	3280	T=0.6729	C=0.3271
MxGDAR/Encodat-PGx	MxGDAR	Sub	3280	T=0.6729	C=0.3271
KOREAN population from KRGDB	KOREAN	Study-wide	2930	T=0.7304	C=0.2696
HapMap	Global	Study-wide	1886	T=0.8054	C=0.1946
HapMap	American	Sub	766	T=0.828	C=0.172
HapMap	African	Sub	690	T=0.810	C=0.190
HapMap	Asian	Sub	254	T=0.744	C=0.256
HapMap	Europe	Sub	176	T=0.778	C=0.222
Korean Genome Project	KOREAN	Study-wide	1832	T=0.7364	C=0.2636
Genome-wide autozygosity in Daghestan	Global	Study-wide	1122	T=0.8164	C=0.1836
Genome-wide autozygosity in Daghestan	Daghestan	Sub	620	T=0.787	C=0.213
Genome-wide autozygosity in Daghestan	Near_East	Sub	140	T=0.843	C=0.157
Genome-wide autozygosity in Daghestan	Central Asia	Sub	120	T=0.850	C=0.150
Genome-wide autozygosity in Daghestan	Europe	Sub	108	T=0.796	C=0.204
Genome-wide autozygosity in Daghestan	South Asian	Sub	98	T=0.96	C=0.04
Genome-wide autozygosity in Daghestan	Caucasus	Sub	36	T=0.78	C=0.22
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	T=0.783	C=0.217
CNV burdens in cranial meningiomas	Global	Study-wide	764	T=0.742	C=0.258
CNV burdens in cranial meningiomas	CRM	Sub	764	T=0.742	C=0.258
PharmGKB Aggregated	Global	Study-wide	734	T=0.826	C=0.174
PharmGKB Aggregated	PA149743821	Sub	356	T=0.775	C=0.225
PharmGKB Aggregated	PA141829933	Sub	190	T=0.837	C=0.163
PharmGKB Aggregated	PA141093253	Sub	188	T=0.910	C=0.090
A Vietnamese Genetic Variation Database	Global	Study-wide	614	T=0.777	C=0.223
Northern Sweden	ACPOP	Study-wide	600	T=0.820	C=0.180
Medical Genome Project healthy controls from Spanish population	Spanish controls	Study-wide	534	T=0.794	C=0.206
FINRISK	Finnish from FINRISK project	Study-wide	304	T=0.859	C=0.141
SGDP_PRJ	Global	Study-wide	240	T=0.417	C=0.583
Qatari	Global	Study-wide	216	T=0.796	C=0.204
The Danish reference pan genome	Danish	Study-wide	40	T=0.90	C=0.10
Siberian	Global	Study-wide	24	T=0.46	C=0.54

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 1	NC_000001.11:g.97515839T>A
GRCh38.p14 chr 1	NC_000001.11:g.97515839T>C
GRCh38.p14 chr 1	NC_000001.11:g.97515839T>G
GRCh37.p13 chr 1	NC_000001.10:g.97981395T>A
GRCh37.p13 chr 1	NC_000001.10:g.97981395T>C
GRCh37.p13 chr 1	NC_000001.10:g.97981395T>G
DPYD RefSeqGene (LRG_722)	NG_008807.2:g.410221A>T
DPYD RefSeqGene (LRG_722)	NG_008807.2:g.410221A>G
DPYD RefSeqGene (LRG_722)	NG_008807.2:g.410221A>C

Gene: DPYD, dihydropyrimidine dehydrogenase (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
DPYD transcript variant 2	NM_001160301.1:c.	N/A	Genic Downstream Transcript Variant
DPYD transcript variant 1	NM_000110.4:c.1627A>T	I [ATA] > L [TTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform 1	NP_000101.2:p.Ile543Leu	I (Ile) > L (Leu)	Missense Variant
DPYD transcript variant 1	NM_000110.4:c.1627A>G	I [ATA] > V [GTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform 1	NP_000101.2:p.Ile543Val	I (Ile) > V (Val)	Missense Variant
DPYD transcript variant 1	NM_000110.4:c.1627A>C	I [ATA] > L [CTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform 1	NP_000101.2:p.Ile543Leu	I (Ile) > L (Leu)	Missense Variant
DPYD transcript variant X2	XM_005270562.3:c.1524+337… XM_005270562.3:c.1524+33721A>T	N/A	Intron Variant
DPYD transcript variant X4	XM_047448077.1:c.1413+337… XM_047448077.1:c.1413+33721A>T	N/A	Intron Variant
DPYD transcript variant X1	XM_017000507.2:c.1516A>T	I [ATA] > L [TTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X1	XP_016855996.1:p.Ile506Leu	I (Ile) > L (Leu)	Missense Variant
DPYD transcript variant X1	XM_017000507.2:c.1516A>G	I [ATA] > V [GTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X1	XP_016855996.1:p.Ile506Val	I (Ile) > V (Val)	Missense Variant
DPYD transcript variant X1	XM_017000507.2:c.1516A>C	I [ATA] > L [CTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X1	XP_016855996.1:p.Ile506Leu	I (Ile) > L (Leu)	Missense Variant
DPYD transcript variant X3	XM_047448076.1:c.1399A>T	I [ATA] > L [TTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X3	XP_047304032.1:p.Ile467Leu	I (Ile) > L (Leu)	Missense Variant
DPYD transcript variant X3	XM_047448076.1:c.1399A>G	I [ATA] > V [GTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X3	XP_047304032.1:p.Ile467Val	I (Ile) > V (Val)	Missense Variant
DPYD transcript variant X3	XM_047448076.1:c.1399A>C	I [ATA] > L [CTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X3	XP_047304032.1:p.Ile467Leu	I (Ile) > L (Leu)	Missense Variant
DPYD transcript variant X5	XM_006710397.4:c.1627A>T	I [ATA] > L [TTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X5	XP_006710460.1:p.Ile543Leu	I (Ile) > L (Leu)	Missense Variant
DPYD transcript variant X5	XM_006710397.4:c.1627A>G	I [ATA] > V [GTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X5	XP_006710460.1:p.Ile543Val	I (Ile) > V (Val)	Missense Variant
DPYD transcript variant X5	XM_006710397.4:c.1627A>C	I [ATA] > L [CTA]	Coding Sequence Variant
dihydropyrimidine dehydrogenase [NADP(+)] isoform X5	XP_006710460.1:p.Ile543Leu	I (Ile) > L (Leu)	Missense Variant
DPYD transcript variant X6	XR_001737014.2:n.	N/A	Genic Downstream Transcript Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Allele: C (allele ID: 105969 )

ClinVar Accession	Disease Names	Clinical Significance
RCV000086475.10	not provided	Benign
RCV000174446.9	not specified	Benign
RCV000389596.10	Dihydropyrimidine dehydrogenase deficiency	Benign
RCV001787907.2	capecitabine response - Toxicity	Drug-Response
RCV001787908.2	fluorouracil response - Toxicity	Drug-Response
RCV003891586.1	DPYD-related disorder	Likely-Benign

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	T=	A	C	G
GRCh38.p14 chr 1	NC_000001.11:g.97515839=	NC_000001.11:g.97515839T>A	NC_000001.11:g.97515839T>C	NC_000001.11:g.97515839T>G
GRCh37.p13 chr 1	NC_000001.10:g.97981395=	NC_000001.10:g.97981395T>A	NC_000001.10:g.97981395T>C	NC_000001.10:g.97981395T>G
DPYD RefSeqGene (LRG_722)	NG_008807.2:g.410221=	NG_008807.2:g.410221A>T	NG_008807.2:g.410221A>G	NG_008807.2:g.410221A>C
DPYD transcript variant 1	NM_000110.4:c.1627=	NM_000110.4:c.1627A>T	NM_000110.4:c.1627A>G	NM_000110.4:c.1627A>C
DPYD transcript variant 1	NM_000110.3:c.1627=	NM_000110.3:c.1627A>T	NM_000110.3:c.1627A>G	NM_000110.3:c.1627A>C
DPYD transcript variant X5	XM_006710397.4:c.1627=	XM_006710397.4:c.1627A>T	XM_006710397.4:c.1627A>G	XM_006710397.4:c.1627A>C
DPYD transcript variant X3	XM_006710397.3:c.1627=	XM_006710397.3:c.1627A>T	XM_006710397.3:c.1627A>G	XM_006710397.3:c.1627A>C
DPYD transcript variant X2	XM_006710397.2:c.1627=	XM_006710397.2:c.1627A>T	XM_006710397.2:c.1627A>G	XM_006710397.2:c.1627A>C
DPYD transcript variant X3	XM_006710397.1:c.1627=	XM_006710397.1:c.1627A>T	XM_006710397.1:c.1627A>G	XM_006710397.1:c.1627A>C
DPYD transcript variant X1	XM_017000507.2:c.1516=	XM_017000507.2:c.1516A>T	XM_017000507.2:c.1516A>G	XM_017000507.2:c.1516A>C
DPYD transcript variant X1	XM_017000507.1:c.1516=	XM_017000507.1:c.1516A>T	XM_017000507.1:c.1516A>G	XM_017000507.1:c.1516A>C
DPYD transcript variant X3	XM_047448076.1:c.1399=	XM_047448076.1:c.1399A>T	XM_047448076.1:c.1399A>G	XM_047448076.1:c.1399A>C
dihydropyrimidine dehydrogenase [NADP(+)] isoform 1	NP_000101.2:p.Ile543=	NP_000101.2:p.Ile543Leu	NP_000101.2:p.Ile543Val	NP_000101.2:p.Ile543Leu
dihydropyrimidine dehydrogenase [NADP(+)] isoform X5	XP_006710460.1:p.Ile543=	XP_006710460.1:p.Ile543Leu	XP_006710460.1:p.Ile543Val	XP_006710460.1:p.Ile543Leu
dihydropyrimidine dehydrogenase [NADP(+)] isoform X1	XP_016855996.1:p.Ile506=	XP_016855996.1:p.Ile506Leu	XP_016855996.1:p.Ile506Val	XP_016855996.1:p.Ile506Leu
dihydropyrimidine dehydrogenase [NADP(+)] isoform X3	XP_047304032.1:p.Ile467=	XP_047304032.1:p.Ile467Leu	XP_047304032.1:p.Ile467Val	XP_047304032.1:p.Ile467Leu
DPYD transcript variant X2	XM_005270562.1:c.1524+33721=	XM_005270562.1:c.1524+33721A>T	XM_005270562.1:c.1524+33721A>G	XM_005270562.1:c.1524+33721A>C
DPYD transcript variant X2	XM_005270562.3:c.1524+33721=	XM_005270562.3:c.1524+33721A>T	XM_005270562.3:c.1524+33721A>G	XM_005270562.3:c.1524+33721A>C
DPYD transcript variant X4	XM_047448077.1:c.1413+33721=	XM_047448077.1:c.1413+33721A>T	XM_047448077.1:c.1413+33721A>G	XM_047448077.1:c.1413+33721A>C

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

186 SubSNP, 30 Frequency, 6 ClinVar submissions

No	Submitter	Submission ID	Date (Build)
1	HGBASE	ss2421380	Nov 14, 2000 (89)
2	SC_JCM	ss3982388	Sep 28, 2001 (100)
3	CSHL-HAPMAP	ss19122795	Feb 27, 2004 (120)
4	SSAHASNP	ss20586053	Apr 05, 2004 (121)
5	PERLEGEN	ss23838612	Sep 20, 2004 (123)
6	SSAHASNP	ss35437363	May 24, 2005 (125)
7	ABI	ss44089633	Mar 14, 2006 (126)
8	CSHL-HAPMAP	ss68406698	Jan 12, 2007 (127)
9	ILLUMINA	ss74886266	Dec 07, 2007 (129)
10	CGM_KYOTO	ss76875524	Dec 07, 2007 (129)
11	HGSV	ss77448282	Dec 07, 2007 (129)
12	PHARMGKB_AB_DME	ss84156629	Dec 15, 2007 (130)
13	PHARMGKB_CREATE	ss84172826	Dec 15, 2007 (130)
14	PHARMGKB_CREATE	ss84172908	Dec 15, 2007 (130)
15	CORNELL	ss86240876	Mar 23, 2008 (129)
16	CANCER-GENOME	ss86342031	Mar 23, 2008 (129)
17	HUMANGENOME_JCVI	ss99231636	Feb 05, 2009 (130)
18	BGI	ss102766433	Dec 01, 2009 (131)
19	SNP500CANCER	ss105439819	Feb 05, 2009 (130)
20	1000GENOMES	ss108441687	Jan 23, 2009 (130)
21	KRIBB_YJKIM	ss119404002	Dec 01, 2009 (131)
22	ENSEMBL	ss138846139	Dec 01, 2009 (131)
23	ILLUMINA	ss153736635	Dec 01, 2009 (131)
24	GMI	ss155397287	Dec 01, 2009 (131)
25	ILLUMINA	ss159329791	Dec 01, 2009 (131)
26	SEATTLESEQ	ss159698107	Dec 01, 2009 (131)
27	ILLUMINA	ss160462985	Dec 01, 2009 (131)
28	ILLUMINA	ss172925350	Jul 04, 2010 (132)
29	BUSHMAN	ss198816788	Jul 04, 2010 (132)
30	1000GENOMES	ss218541484	Jul 14, 2010 (132)
31	1000GENOMES	ss230651190	Jul 14, 2010 (132)
32	1000GENOMES	ss238319803	Jul 15, 2010 (132)
33	GMI	ss275940442	May 04, 2012 (137)
34	PJP	ss290578062	May 09, 2011 (134)
35	NHLBI-ESP	ss341976658	May 09, 2011 (134)
36	ILLUMINA	ss480300884	May 04, 2012 (137)
37	ILLUMINA	ss480311995	May 04, 2012 (137)
38	ILLUMINA	ss481067734	Sep 08, 2015 (146)
39	ILLUMINA	ss484948254	May 04, 2012 (137)
40	1000GENOMES	ss489753576	May 04, 2012 (137)
41	EXOME_CHIP	ss491297116	May 04, 2012 (137)
42	CLINSEQ_SNP	ss491598680	May 04, 2012 (137)
43	ILLUMINA	ss536992430	Sep 08, 2015 (146)
44	TISHKOFF	ss554467406	Apr 25, 2013 (138)
45	SSMP	ss648244219	Apr 25, 2013 (138)
46	ILLUMINA	ss778467814	Sep 08, 2015 (146)
47	ILLUMINA	ss780879266	Sep 08, 2015 (146)
48	ILLUMINA	ss782920435	Sep 08, 2015 (146)
49	ILLUMINA	ss783564858	Sep 08, 2015 (146)
50	ILLUMINA	ss783883464	Sep 08, 2015 (146)
51	ILLUMINA	ss832175561	Sep 08, 2015 (146)
52	ILLUMINA	ss832841800	Jul 12, 2019 (153)
53	ILLUMINA	ss833923573	Sep 08, 2015 (146)
54	JMKIDD_LAB	ss974436254	Aug 21, 2014 (142)
55	EVA-GONL	ss975467720	Aug 21, 2014 (142)
56	JMKIDD_LAB	ss1067423558	Aug 21, 2014 (142)
57	JMKIDD_LAB	ss1068116812	Aug 21, 2014 (142)
58	1000GENOMES	ss1292050672	Aug 21, 2014 (142)
59	HAMMER_LAB	ss1397254771	Sep 08, 2015 (146)
60	CLINVAR	ss1536213404	Dec 17, 2014 (142)
61	EVA_GENOME_DK	ss1574260100	Apr 01, 2015 (144)
62	EVA_FINRISK	ss1584009481	Apr 01, 2015 (144)
63	EVA_DECODE	ss1584845227	Apr 01, 2015 (144)
64	EVA_UK10K_ALSPAC	ss1600786065	Apr 01, 2015 (144)
65	EVA_UK10K_TWINSUK	ss1643780098	Apr 01, 2015 (144)
66	EVA_EXAC	ss1685650016	Apr 01, 2015 (144)
67	EVA_MGP	ss1710913145	Apr 01, 2015 (144)
68	EVA_SVP	ss1712356107	Apr 01, 2015 (144)
69	ILLUMINA	ss1751941124	Sep 08, 2015 (146)
70	ILLUMINA	ss1751941125	Sep 08, 2015 (146)
71	HAMMER_LAB	ss1794788494	Sep 08, 2015 (146)
72	ILLUMINA	ss1917731613	Feb 12, 2016 (147)
73	WEILL_CORNELL_DGM	ss1918668191	Feb 12, 2016 (147)
74	ILLUMINA	ss1946002602	Feb 12, 2016 (147)
75	ILLUMINA	ss1958296016	Feb 12, 2016 (147)
76	GENOMED	ss1966817495	Jul 19, 2016 (147)
77	JJLAB	ss2019855401	Sep 14, 2016 (149)
78	USC_VALOUEV	ss2147874211	Dec 20, 2016 (150)
79	HUMAN_LONGEVITY	ss2164907364	Dec 20, 2016 (150)
80	ILLUMINA	ss2632551895	Nov 08, 2017 (151)
81	ILLUMINA	ss2632551896	Nov 08, 2017 (151)
82	GRF	ss2697801375	Nov 08, 2017 (151)
83	GNOMAD	ss2731657054	Nov 08, 2017 (151)
84	GNOMAD	ss2746378480	Nov 08, 2017 (151)
85	GNOMAD	ss2758472821	Nov 08, 2017 (151)
86	AFFY	ss2984868258	Nov 08, 2017 (151)
87	AFFY	ss2985519686	Nov 08, 2017 (151)
88	SWEGEN	ss2987283131	Nov 08, 2017 (151)
89	ILLUMINA	ss3021112893	Nov 08, 2017 (151)
90	BIOINF_KMB_FNS_UNIBA	ss3023691376	Nov 08, 2017 (151)
91	CSIRBIOHTS	ss3029637195	Nov 08, 2017 (151)
92	CSHL	ss3343589474	Nov 08, 2017 (151)
93	ILLUMINA	ss3626162233	Oct 11, 2018 (152)
94	ILLUMINA	ss3626162234	Oct 11, 2018 (152)
95	ILLUMINA	ss3630586148	Oct 11, 2018 (152)
96	ILLUMINA	ss3632902617	Oct 11, 2018 (152)
97	ILLUMINA	ss3633597598	Oct 11, 2018 (152)
98	ILLUMINA	ss3634338542	Oct 11, 2018 (152)
99	ILLUMINA	ss3634338543	Oct 11, 2018 (152)
100	ILLUMINA	ss3635291229	Oct 11, 2018 (152)
101	ILLUMINA	ss3636015984	Oct 11, 2018 (152)
102	ILLUMINA	ss3637041682	Oct 11, 2018 (152)
103	ILLUMINA	ss3637774538	Oct 11, 2018 (152)
104	ILLUMINA	ss3640045902	Oct 11, 2018 (152)
105	ILLUMINA	ss3640045903	Oct 11, 2018 (152)
106	ILLUMINA	ss3642784790	Oct 11, 2018 (152)
107	ILLUMINA	ss3644498562	Oct 11, 2018 (152)
108	OMUKHERJEE_ADBS	ss3646233649	Oct 11, 2018 (152)
109	URBANLAB	ss3646728707	Oct 11, 2018 (152)
110	ILLUMINA	ss3651443539	Oct 11, 2018 (152)
111	ILLUMINA	ss3653640135	Oct 11, 2018 (152)
112	EGCUT_WGS	ss3655365997	Jul 12, 2019 (153)
113	EVA_DECODE	ss3687339920	Jul 12, 2019 (153)
114	ILLUMINA	ss3725047287	Jul 12, 2019 (153)
115	ACPOP	ss3727301573	Jul 12, 2019 (153)
116	ILLUMINA	ss3744348639	Jul 12, 2019 (153)
117	ILLUMINA	ss3744639515	Jul 12, 2019 (153)
118	ILLUMINA	ss3744639516	Jul 12, 2019 (153)
119	EVA	ss3746557523	Jul 12, 2019 (153)
120	PAGE_CC	ss3770827369	Jul 12, 2019 (153)
121	ILLUMINA	ss3772140753	Jul 12, 2019 (153)
122	ILLUMINA	ss3772140754	Jul 12, 2019 (153)
123	KHV_HUMAN_GENOMES	ss3799558807	Jul 12, 2019 (153)
124	EVA	ss3823633527	Apr 25, 2020 (154)
125	EVA	ss3825570042	Apr 25, 2020 (154)
126	EVA	ss3836550169	Apr 25, 2020 (154)
127	EVA	ss3841958111	Apr 25, 2020 (154)
128	SGDP_PRJ	ss3849449452	Apr 25, 2020 (154)
129	KRGDB	ss3894524199	Apr 25, 2020 (154)
130	KOGIC	ss3945066550	Apr 25, 2020 (154)
131	FSA-LAB	ss3983938255	Apr 25, 2021 (155)
132	EVA	ss3984447085	Apr 25, 2021 (155)
133	EVA	ss3984461558	Apr 25, 2021 (155)
134	EVA	ss3986011494	Apr 25, 2021 (155)
135	EVA	ss3986128440	Apr 25, 2021 (155)
136	EVA	ss4016926875	Apr 25, 2021 (155)
137	TOPMED	ss4460167776	Apr 25, 2021 (155)
138	EVA	ss6208439126	Nov 02, 2024 (157)
139	EVA	ss6284041439	Nov 02, 2024 (157)
140	EVA	ss6321858170	Nov 02, 2024 (157)
141	EVA	ss6322091891	Nov 02, 2024 (157)
142	EVA	ss6322917217	Nov 02, 2024 (157)
143	EVA	ss6329345084	Nov 02, 2024 (157)
144	YEGNASUBRAMANIAN_LAB	ss6334273958	Nov 02, 2024 (157)
145	EVA	ss6349481102	Nov 02, 2024 (157)
146	KOGIC	ss6352002860	Nov 02, 2024 (157)
147	EVA	ss6403965867	Nov 02, 2024 (157)
148	EVA	ss6404017287	Nov 02, 2024 (157)
149	EVA	ss6404635375	Nov 02, 2024 (157)
150	GNOMAD	ss6407780012	Nov 02, 2024 (157)
151	GNOMAD	ss6494946379	Nov 02, 2024 (157)
152	TOMMO_GENOMICS	ss8145250573	Nov 02, 2024 (157)
153	EVA	ss8236871142	Nov 02, 2024 (157)
154	EVA	ss8237632436	Nov 02, 2024 (157)
155	1000G_HIGH_COVERAGE	ss8243273599	Nov 02, 2024 (157)
156	TRAN_CS_UWATERLOO	ss8314396341	Nov 02, 2024 (157)
157	EVA	ss8314637095	Nov 02, 2024 (157)
158	EVA	ss8320581272	Nov 02, 2024 (157)
159	HUGCELL_USP	ss8444230361	Nov 02, 2024 (157)
160	EVA	ss8505960280	Nov 02, 2024 (157)
161	EVA	ss8512473810	Nov 02, 2024 (157)
162	1000G_HIGH_COVERAGE	ss8516087425	Nov 02, 2024 (157)
163	EVA	ss8623994841	Nov 02, 2024 (157)
164	SANFORD_IMAGENETICS	ss8624212890	Nov 02, 2024 (157)
165	SANFORD_IMAGENETICS	ss8626104704	Nov 02, 2024 (157)
166	TOMMO_GENOMICS	ss8670392632	Nov 02, 2024 (157)
167	EVA	ss8799409415	Nov 02, 2024 (157)
168	EVA	ss8799493101	Nov 02, 2024 (157)
169	EVA	ss8800083414	Nov 02, 2024 (157)
170	YY_MCH	ss8800848542	Nov 02, 2024 (157)
171	EVA	ss8832352870	Nov 02, 2024 (157)
172	EVA	ss8847163582	Nov 02, 2024 (157)
173	EVA	ss8847548162	Nov 02, 2024 (157)
174	EVA	ss8848266000	Nov 02, 2024 (157)
175	EVA	ss8849028461	Nov 02, 2024 (157)
176	EVA	ss8909416534	Nov 02, 2024 (157)
177	EVA	ss8935519180	Nov 02, 2024 (157)
178	EVA	ss8937963553	Nov 02, 2024 (157)
179	EVA	ss8979283118	Nov 02, 2024 (157)
180	EVA	ss8981195252	Nov 02, 2024 (157)
181	EVA	ss8981700533	Nov 02, 2024 (157)
182	EVA	ss8981700534	Nov 02, 2024 (157)
183	EVA	ss8982017096	Nov 02, 2024 (157)
184	LNCC-LABINFO	ss8982072043	Nov 02, 2024 (157)
185	EVA	ss8982330850	Nov 02, 2024 (157)
186	TOMMO_GENOMICS	ss8989732409	Nov 02, 2024 (157)
187	1000Genomes	NC_000001.10 - 97981395	Oct 11, 2018 (152)
188	1000Genomes_30X	NC_000001.11 - 97515839	Nov 02, 2024 (157)
189	The Avon Longitudinal Study of Parents and Children	NC_000001.10 - 97981395	Oct 11, 2018 (152)
190	Genome-wide autozygosity in Daghestan	NC_000001.9 - 97753983	Apr 25, 2020 (154)
191	Genetic variation in the Estonian population	NC_000001.10 - 97981395	Oct 11, 2018 (152)
192	ExAC	NC_000001.10 - 97981395	Oct 11, 2018 (152)
193	FINRISK	NC_000001.10 - 97981395	Apr 25, 2020 (154)
194	The Danish reference pan genome	NC_000001.10 - 97981395	Apr 25, 2020 (154)
195	gnomAD v4 - Exomes	NC_000001.11 - 97515839	Nov 02, 2024 (157)
196	gnomAD v4 - Genomes	NC_000001.11 - 97515839	Nov 02, 2024 (157)
197	GO Exome Sequencing Project	NC_000001.10 - 97981395	Oct 11, 2018 (152)
198	Genome of the Netherlands Release 5	NC_000001.10 - 97981395	Apr 25, 2020 (154)
199	HapMap	NC_000001.11 - 97515839	Apr 25, 2020 (154)
200	KOREAN population from KRGDB	NC_000001.10 - 97981395	Apr 25, 2020 (154)
201	Korean Genome Project	NC_000001.11 - 97515839	Apr 25, 2020 (154)
202	Korean Genome Project 4K	NC_000001.11 - 97515839	Nov 02, 2024 (157)
203	Medical Genome Project healthy controls from Spanish population	NC_000001.10 - 97981395	Apr 25, 2020 (154)
204	Northern Sweden	NC_000001.10 - 97981395	Jul 12, 2019 (153)
205	The PAGE Study	NC_000001.11 - 97515839	Jul 12, 2019 (153)
206	CNV burdens in cranial meningiomas	NC_000001.10 - 97981395	Apr 25, 2021 (155)
207	MxGDAR/Encodat-PGx	NC_000001.10 - 97981395	Apr 25, 2021 (155)
208	PharmGKB Aggregated	NC_000001.11 - 97515839	Apr 25, 2020 (154)
209	Qatari	NC_000001.10 - 97981395	Apr 25, 2020 (154)
210	SGDP_PRJ	NC_000001.10 - 97981395	Apr 25, 2020 (154)
211	Siberian	NC_000001.10 - 97981395	Apr 25, 2020 (154)
212	38KJPN	NC_000001.11 - 97515839	Nov 02, 2024 (157)
213	TopMed	NC_000001.11 - 97515839	Apr 25, 2021 (155)
214	UK 10K study - Twins	NC_000001.10 - 97981395	Oct 11, 2018 (152)
215	A Vietnamese Genetic Variation Database	NC_000001.10 - 97981395	Jul 12, 2019 (153)
216	ALFA	NC_000001.11 - 97515839	Nov 02, 2024 (157)
217	ClinVar	RCV000086475.10	Nov 02, 2024 (157)
218	ClinVar	RCV000174446.9	Nov 02, 2024 (157)
219	ClinVar	RCV000389596.10	Nov 02, 2024 (157)
220	ClinVar	RCV001787907.2	Nov 02, 2024 (157)
221	ClinVar	RCV001787908.2	Nov 02, 2024 (157)
222	ClinVar	RCV003891586.1	Nov 02, 2024 (157)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs17116825	Oct 07, 2004 (123)
rs58945530	May 25, 2008 (130)
rs117999026	Aug 16, 2010 (132)
rs199469541	Dec 28, 2011 (136)
rs386545620	Aug 21, 2014 (142)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss6349481102, ss8512473810, ss8935519180	NC_000001.10:97981394:T:A	NC_000001.11:97515838:T:A	(self)
ss35437363, ss77448282	NC_000001.8:97693415:T:C	NC_000001.11:97515838:T:C	(self)
16078, ss108441687, ss198816788, ss275940442, ss290578062, ss480300884, ss491598680, ss1397254771, ss1584845227, ss1712356107, ss3642784790	NC_000001.9:97753982:T:C	NC_000001.11:97515838:T:C	(self)
2812337, 1550226, 1104245, 4855926, 5942, 1622887, 92161, 672108, 1701593, 29897, 586438, 10870, 86, 710121, 1466432, 390565, 1550226, 333654, ss218541484, ss230651190, ss238319803, ss341976658, ss480311995, ss481067734, ss484948254, ss489753576, ss491297116, ss536992430, ss554467406, ss648244219, ss778467814, ss780879266, ss782920435, ss783564858, ss783883464, ss832175561, ss832841800, ss833923573, ss974436254, ss975467720, ss1067423558, ss1068116812, ss1292050672, ss1574260100, ss1584009481, ss1600786065, ss1643780098, ss1685650016, ss1710913145, ss1751941124, ss1751941125, ss1794788494, ss1917731613, ss1918668191, ss1946002602, ss1958296016, ss1966817495, ss2019855401, ss2147874211, ss2632551895, ss2632551896, ss2697801375, ss2731657054, ss2746378480, ss2758472821, ss2984868258, ss2985519686, ss2987283131, ss3021112893, ss3029637195, ss3343589474, ss3626162233, ss3626162234, ss3630586148, ss3632902617, ss3633597598, ss3634338542, ss3634338543, ss3635291229, ss3636015984, ss3637041682, ss3637774538, ss3640045902, ss3640045903, ss3644498562, ss3646233649, ss3651443539, ss3653640135, ss3655365997, ss3727301573, ss3744348639, ss3744639515, ss3744639516, ss3746557523, ss3772140753, ss3772140754, ss3823633527, ss3825570042, ss3836550169, ss3849449452, ss3894524199, ss3983938255, ss3984447085, ss3984461558, ss3986011494, ss3986128440, ss4016926875, ss6208439126, ss6284041439, ss6322091891, ss6322917217, ss6329345084, ss6334273958, ss6403965867, ss6404635375, ss8145250573, ss8314637095, ss8320581272, ss8505960280, ss8512473810, ss8623994841, ss8624212890, ss8626104704, ss8799409415, ss8799493101, ss8800083414, ss8832352870, ss8847163582, ss8847548162, ss8848266000, ss8935519180, ss8937963553, ss8979283118, ss8981195252, ss8981700533, ss8981700534, ss8982330850	NC_000001.10:97981394:T:C	NC_000001.11:97515838:T:C	(self)
RCV000086475.10, RCV000174446.9, RCV000389596.10, RCV001787907.2, RCV001787908.2, RCV003891586.1, 3613360, 3078345, 21261151, 133544, 1444551, 1854758, 48838, 317, 7108229, 23774111, 906233569, ss1536213404, ss2164907364, ss3023691376, ss3646728707, ss3687339920, ss3725047287, ss3770827369, ss3799558807, ss3841958111, ss3945066550, ss4460167776, ss6321858170, ss6352002860, ss6404017287, ss6407780012, ss6494946379, ss8236871142, ss8237632436, ss8243273599, ss8314396341, ss8444230361, ss8516087425, ss8670392632, ss8800848542, ss8849028461, ss8909416534, ss8982017096, ss8982072043, ss8989732409	NC_000001.11:97515838:T:C	NC_000001.11:97515838:T:C	(self)
ss19122795, ss20586053	NT_028050.13:6170338:T:C	NC_000001.11:97515838:T:C	(self)
ss2421380, ss3982388, ss23838612, ss44089633, ss68406698, ss74886266, ss76875524, ss84156629, ss84172826, ss84172908, ss86240876, ss86342031, ss99231636, ss102766433, ss105439819, ss119404002, ss138846139, ss153736635, ss155397287, ss159329791, ss159698107, ss160462985, ss172925350	NT_032977.9:67953312:T:C	NC_000001.11:97515838:T:C	(self)
ss6349481102, ss8935519180	NC_000001.10:97981394:T:G	NC_000001.11:97515838:T:G	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

26 citations for rs1801159

PMID	Title	Author	Year	Journal
19104657	Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.	Gross E et al.	2008	PloS one
21362212	[Detection of single nucleotide polymorphisms of mthfr and dpyd genes in leukemia cell lines K562 and K562/A02].	Zhang WJ et al.	2011	Zhongguo shi yan xue ye xue za zhi
22552919	Bioinformatics and variability in drug response: a protein structural perspective.	Lahti JL et al.	2012	Journal of the Royal Society, Interface
23942539	Potential of dihydropyrimidine dehydrogenase genotypes in personalizing 5-fluorouracil therapy among colorectal cancer patients.	Teh LK et al.	2013	Therapeutic drug monitoring
23988873	Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing.	Caudle KE et al.	2013	Clinical pharmacology and therapeutics
24944790	Screening for 392 polymorphisms in 141 pharmacogenes.	Kim JY et al.	2014	Biomedical reports
25027354	Thymidine phosphorylase gene variant, platelet counts and survival in gastrointestinal cancer patients treated by fluoropyrimidines.	Huang L et al.	2014	Scientific reports
25110414	Pharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 years.	Panczyk M et al.	2014	World journal of gastroenterology
25741868	Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.	Richards S et al.	2015	Genetics in medicine
25746798	Technical reproducibility of single-nucleotide and size-based DNA biomarker assessment using DNA extracted from formalin-fixed, paraffin-embedded tissues.	Zhang S et al.	2015	The Journal of molecular diagnostics
26099996	Clinical validity of a DPYD-based pharmacogenetic test to predict severe toxicity to fluoropyrimidines.	Toffoli G et al.	2015	International journal of cancer
26801900	Pharmacogenetics driving personalized medicine: analysis of genetic polymorphisms related to breast cancer medications in Italian isolated populations.	Cocca M et al.	2016	Journal of translational medicine
29065426	Dihydropyrimidine dehydrogenase pharmacogenetics for predicting fluoropyrimidine-related toxicity in the randomised, phase III adjuvant TOSCA trial in high-risk colon cancer patients.	Ruzzo A et al.	2017	British journal of cancer
29193749	Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years.	Borobia AM et al.	2018	Clinical and translational science
29372689	DPYD genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from Slovakia.	Matáková T et al.	2017	General physiology and biophysics
32311112	Analysis of very important pharmacogene variants in the Tibetan population from China.	Rong H et al.	2021	Clinical and experimental pharmacology & physiology
32619063	Impact of DPYD, DPYS, and UPB1 gene variations on severe drug-related toxicity in patients with cancer.	Yokoi K et al.	2020	Cancer science
33194059	Polymorphisms of xenobiotic-metabolizing and transporter genes, and the risk of gastric and colorectal cancer in an admixed population from the Brazilian Amazon.	de Castro ANCL et al.	2020	American journal of translational research
34429635	Population Genetic Difference of Pharmacogenomic VIP Variants in the Tibetan Population.	He C et al.	2021	Pharmacogenomics and personalized medicine
34798807	Genetic analysis of pharmacogenomic VIP variants in the Wa population from Yunnan Province of China.	Li D et al.	2021	BMC genomic data
34949935	Genetic Polymorphisms of Very Important Pharmacogene Variants in the Blang Population from Yunnan Province in China.	Wang Y et al.	2021	Pharmacogenomics and personalized medicine
35582139	The use of pharmacogenetics to increase the safety of colorectal cancer patients treated with fluoropyrimidines.	De Mattia E et al.	2019	Cancer drug resistance (Alhambra, Calif.)
35743735	Genetic Variations of the DPYD Gene and Its Relationship with Ancestry Proportions in Different Ecuadorian Trihybrid Populations.	Farinango C et al.	2022	Journal of personalized medicine
35743738	Pharmacogenomic Profile of Amazonian Amerindians.	Rodrigues JCG et al.	2022	Journal of personalized medicine
36980706	Influence of Single-Nucleotide Polymorphisms on Clinical Outcomes of Capecitabine-Based Chemotherapy in Colorectal Cancer Patients: A Systematic Review.	Cura Y et al.	2023	Cancers
37835382	Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments.	Garcia-Etxebarria K et al.	2023	Cancers

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs1801159