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Select item 119138861.

Pharmacokinetic Profiles of Lansoprazole in Patients With Morbid Obesity Post‐Roux‐en‐Y Gastric Bypass Surgery

Suthep Udomsawaengsup, Sathienrapong Chantawibul, Naranon Boonyuen, Sarunnuch Panyavorakhunchai, Pattharasai Kachornvitaya, Wasu Wisanuyothin, Pittawat Somvanapanich, Warittha Lertwatthiphong, Napatsanan Tanathitiphuwarat, Pajaree Chariyavilaskul

Clin Transl Sci. 2025 Mar; 18(3): e70200. Published online 2025 Mar 17. doi: 10.1111/cts.70200

PMCID:: PMC11913886

Article PDF–1.0M

Select item 119115992.

Predicting Pharmacokinetics in Rats Using Machine Learning: A Comparative Study Between Empirical, Compartmental, and PBPK‐Based Approaches

Moritz Walter, Ghaith Aljayyoussi, Bettina Gerner, Hermann Rapp, Christofer S. Tautermann, Pavel Balazki, Miha Skalic, Jens M. Borghardt, Lina Humbeck

Clin Transl Sci. 2025 Mar; 18(3): e70150. Published online 2025 Mar 17. doi: 10.1111/cts.70150

PMCID:: PMC11911599

Article PDF–457K

Select item 119064853.

First‐In‐Human Safety, Tolerability, and Pharmacokinetics of PPI‐1011, a Synthetic Plasmalogen Precursor

Tara Smith, Kaeli J. Knudsen, Shawn A. Ritchie

Clin Transl Sci. 2025 Mar; 18(3): e70195. Published online 2025 Mar 13. doi: 10.1111/cts.70195

PMCID:: PMC11906485

Article PDF–1.3M

Select item 119035014.

Evaluating the Effect of Epigallocatechin Gallate (EGCG) in Reducing Folate Levels in Reproductive Aged Women by MTHFR and DHFR Genotype in Combination With Letrozole or Clomiphene

Jeremy J. Johnson, Hiba Siblini, Ayman Al‐Hendy, James H. Segars, Frank González, Hugh S. Taylor, Bhuchitra Singh, Sandra A. Carson, Gregory M. Christman, Hao Huang, Bikash Dangi, Heping Zhang

Clin Transl Sci. 2025 Mar; 18(3): e70189. Published online 2025 Mar 12. doi: 10.1111/cts.70189

PMCID:: PMC11903501

Article PDF–424K

Select item 119033275.

Assessment of Food Effect and pH‐Dependent Drug–Drug Interactions of Fruquintinib in Healthy Subjects

Martha Gonzalez, Zhao Yang, William R. Schelman, Xiaofei Zhou, Neeraj Gupta, Caly Chien

Clin Transl Sci. 2025 Mar; 18(3): e70168. Published online 2025 Mar 12. doi: 10.1111/cts.70168

PMCID:: PMC11903327

Article PDF–1.1M

Select item 119033256.

Psoriasis Risk Is Lower in Type 2 Diabetes Patients Using Dipeptidyl Peptidase‐4 Inhibitors or Thiazolidinediones Compared to Sulfonylureas

Wei‐Sheng Chen, Tzu‐Min Lin, Yu‐Sheng Chang, Yu‐Chuan Shen, Hui‐Ching Hsu, Tzu‐Tung Kuo, Shu‐Chuan Chen, Jin‐Hua Chen, Chi‐Ching Chang

Clin Transl Sci. 2025 Mar; 18(3): e70177. Published online 2025 Mar 12. doi: 10.1111/cts.70177

PMCID:: PMC11903325

Article PDF–832K

Select item 118970617.

Establishing a Common Lexicon for Circulating Tumor DNA Analysis and Molecular Residual Disease: Insights From the BLOODPAC Consortium

Andrew G. Hadd, Angela Silvestro, Brittany Avin McKelvey, Jonathan Baden, Christina Bormann Chung, Ben Brown, Fernando Cruz‐Guilloty, James Godsey, Gregory Jones, Cheng‐Ho Jimmy Lin, Dorys Lopez Ramos, Daniel Norton, Melanie R. Palomares, Carol Pena, Thereasa Rich, Angel Rodriguez, Mark Stewart, Diana Merino Vega, Lauren C. Leiman

Clin Transl Sci. 2025 Mar; 18(3): e70185. Published online 2025 Mar 11. doi: 10.1111/cts.70185

PMCID:: PMC11897061

Article PDF–444K

Select item 118937258.

Comparative Effectiveness of Dual Biologic Therapy and Biologic Small‐Molecule Therapy for Refractory Inflammatory Bowel Disease: A Retrospective Single‐Center Study

Fan Yin, Xiaolei Liu, Dongdong He, Songbo Li, Xin Feng, Yongquan Shi, Min Chen

Clin Transl Sci. 2025 Mar; 18(3): e70198. Published online 2025 Mar 10. doi: 10.1111/cts.70198

PMCID:: PMC11893725

Article PDF–415K

Select item 118937239.

Safety, Tolerability, and Pharmacokinetics of SC1011 (Sufenidone), a Novel Antifibrotic Small Molecule, in Phase 1 Studies in Healthy Subjects

Yun Liu, Xiaoning Chen, Huimin Tang, Fan Jiang, Yaqin Tang, Huijuan Zhu, Yanping Du, Hongjie Qian, Shuyun Liu, Xiaoshu Sun, Bin Zan, Yuexia Zeng, Yun Li, Zhen Ge, Yongguo Li, Zhongqi Yang

Clin Transl Sci. 2025 Mar; 18(3): e70179. Published online 2025 Mar 10. doi: 10.1111/cts.70179

PMCID:: PMC11893723

Article PDF–932K

Select item 1188068910.

Transarterial Chemoembolization for Patients With Hepatocellular Carcinoma Using Miriplatin Without the Need for Hydration

Koji Fujita, Kei Takuma, Kyoko Oura, Tomoko Tadokoro, Asahiro Morishita, Takashi Himoto, Hideki Kobara

Clin Transl Sci. 2025 Mar; 18(3): e70182. Published online 2025 Mar 5. doi: 10.1111/cts.70182

PMCID:: PMC11880689

Article PDF–572K

Select item 1188011411.

Pharmacodynamics of Aspirin Through Gestation: Predictors of Aspirin Response and Association With Pregnancy Outcome, a Prospective Cohort Study

Rupsa C. Boelig, Emily Foecke Munden, Tingting Zhan, Steven E. McKenzie, Walter K. Kraft

Clin Transl Sci. 2025 Mar; 18(3): e70167. Published online 2025 Mar 4. doi: 10.1111/cts.70167

PMCID:: PMC11880114

Article PDF–588K

Select item 1187629212.

Comparison of the Efficacy and Safety of Disease‐Modifying Antirheumatic Drugs Combination Therapies: A Systematic Review and Network Meta‐Analysis

Linfeng Liu, Kaori Ambe, Mayu Onishi, Yuka Yoshii, Toshiaki Makino, Masahiro Tohkin

Clin Transl Sci. 2025 Mar; 18(3): e70156. Published online 2025 Mar 3. doi: 10.1111/cts.70156

PMCID:: PMC11876292

Article PDF–894K

Select item 1187336513.

Population Pharmacokinetic and Exposure–Response Analyses for Ponatinib in the Phase 3 PhALLCON Study

Michael J. Hanley, Thomas R. Larson, Paul M. Diderichsen, Anna Largajolli, Katrina Hui, Jaydeep Srimani, Bingxia Wang, Alexander Vorog, Neeraj Gupta

Clin Transl Sci. 2025 Mar; 18(3): e70175. Published online 2025 Mar 2. doi: 10.1111/cts.70175

PMCID:: PMC11873365

Article PDF–426K

Select item 1186803514.

Evaluation of the Landscape of Pharmacodynamic Biomarkers in GM1 and GM2 Gangliosidosis

Sydney Stern, Karryn Crisamore, Ruo‐Jing Li, Michael Pacanowski, Robert Schuck

Clin Transl Sci. 2025 Mar; 18(3): e70176. Published online 2025 Feb 27. doi: 10.1111/cts.70176

PMCID:: PMC11868035

Article PDF–320K

Select item 1186422815.

Effect of E7777 Immunogenicity on Pharmacokinetics, Efficacy, and Safety in Adult Patients With Relapsed or Refractory Cutaneous T‐Cell Lymphoma

Theingi M. Thway, Jagadeesh Aluri, Bojan Lalovic, Chean E. Ooi, Nicholas Sauter, Dongyuan Xing, Myron Czuczman, Sanae Yasuda

Clin Transl Sci. 2025 Mar; 18(3): e70166. Published online 2025 Feb 26. doi: 10.1111/cts.70166

PMCID:: PMC11864228

Article PDF–322K

Select item 1184660716.

Integrating early response biomarkers in pharmacokinetic models: A novel method to individualize the initial infliximab dose in patients with Crohn's disease

Abigail Samuels, Kei Irie, Tomoyuki Mizuno, Jack Reifenberg, Nieko Punt, Alexander A. Vinks, Phillip Minar

Clin Transl Sci. 2025 Feb; 18(2): e70086. Published online 2025 Feb 22. doi: 10.1111/cts.70086

PMCID:: PMC11846607

Article PDF–723K

Select item 1183939017.

Decentralized Clinical Trials in the Era of Real‐World Evidence: A Statistical Perspective

Jie Chen, Junrui Di, Nadia Daizadeh, Ying Lu, Hongwei Wang, Yuan‐Li Shen, Jennifer Kirk, Frank W. Rockhold, Herbert Pang, Jing Zhao, Weili He, Andrew Potter, Hana Lee

Clin Transl Sci. 2025 Feb; 18(2): e70117. Published online 2025 Feb 19. doi: 10.1111/cts.70117