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Items: 1 to 20 of 63

1.
A RISK-BASED PRIORITIZATION OF PFAS USING PHENOTYPIC AND TRANSCRIPTOMIC DATA FROM HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED HEPATOCYTES AND CARDIOMYOCYTES
Han-Hsuan Doris Tsai, Lucie C. Ford, Zunwei Chen, Allison N. Dickey, Fred A. Wright, Ivan Rusyn
ALTEX. Author manuscript; available in PMC 2024 Aug 7.
Published in final edited form as: ALTEX. 2024; 41(3): 363–381. Published online 2024 Feb 22. doi: 10.14573/altex.2311031
PMCID:
PMC11305846
ArticlePDF–2.4M
2.
Why Adverse Outcome Pathways Need to be FAIR
Clemens Wittwehr, Laure-Alix Clerbaux, Stephen Edwards, Michelle Angrish, Holly Mortensen, Annamaria Carusi, Maciej Gromelski, Eftychia Lekka, Vassilis Virvilis, Marvin Martens, Luiz Olavo Bonino da Silva Santos, Penny Nymark
ALTEX. Author manuscript; available in PMC 2024 Jun 14.
Published in final edited form as: ALTEX. 2024 Jan 9; 41(1): 50–56. Published online 2023 Aug 1. doi: 10.14573/altex.2307131
PMCID:
PMC11177558
ArticlePDF–521K
3.
Development of Physiologically-based Gut Absorption Model for Probabilistic Prediction of Environmental Chemical Bioavailability
Hsing-Chieh Lin, Weihsueh A. Chiu
ALTEX. Author manuscript; available in PMC 2024 Feb 27.
Published in final edited form as: ALTEX. 2023; 40(3): 471–484. Published online 2023 May 3. doi: 10.14573/altex.2210031
PMCID:
PMC10898273
ArticlePDF–1.3M
4.
Development of an Evidence-Based Risk Assessment Framework
Daniel Krewski, Patrick Saunders-Hastings, Robert A. Baan, Tara S. Barton-Maclaren, Patience Browne, Weihsueh A. Chiu, Maureen Gwinn, Thomas Hartung, Andrew D. Kraft, Juleen Lam, R. Jeffrey Lewis, Moez Sanaa, Rebecca L. Morgan, Greg Paoli, Lorenz Rhomberg, Andrew Rooney, Salomon Sand, Holger J. Schünemann, Kurt Straif, Kristina A Thayer, Katya Tsaioun
ALTEX. Author manuscript; available in PMC 2023 Apr 7.
Published in final edited form as: ALTEX. 2022; 39(4): 667–693. Published online 2022 Sep 1. doi: 10.14573/altex.2004041
PMCID:
PMC10080579
ArticlePDF–1.8M
5.
Identifying Candidate Reference Chemicals for In Vitro Testing of the Retinoid Pathway for Predictive Developmental Toxicity
Nancy C. Baker, Jocylin D. Pierro, Laura W. Taylor, Thomas B. Knudsen
ALTEX. Author manuscript; available in PMC 2024 Jan 4.
Published in final edited form as: ALTEX. 2023; 40(2): 217–236. Published online 2022 Jun 23. doi: 10.14573/altex.2202231
PMCID:
PMC10765368
ArticlePDF–1.2M
6.
Beyond Pharmaceuticals: Fit-for-Purpose New Approach Methodologies for Environmental Cardiotoxicity Testing
Mark C. Daley, Ulrike Mende, Bum-Rak Choi, Patrick D. McMullen, Kareen L. K. Coulombe
ALTEX. Author manuscript; available in PMC 2023 Sep 15.
Published in final edited form as: ALTEX. 2023; 40(1): 103–116. Published online 2022 Jun 1. doi: 10.14573/altex.2109131
PMCID:
PMC10502740
ArticlePDF–849K
7.
Application of Evidence-Based Methods to Construct Mechanism-Driven Chemical Assessment Frameworks
Sebastian Hoffmann, Elisa Aiassa, Michelle Angrish, Claire Beausoleil, Frederic Y. Bois, Laura Ciccolallo, Peter S. Craig, Rob B. M. de Vries, Jean Lou C. M. Dorne, Ingrid L. Druwe, Stephen W. Edwards, Chantra Eskes, Marios Georgiadis, Thomas Hartung, Aude Kienzler, Elisabeth A. Kristjansson, Juleen Lam, Laura Martino, Bette Meek, Rebecca L. Morgan, Irene Munoz-Guajardo, Pamela D. Noyes, Elena Parmelli, Aldert Piersma, Andrew Rooney, Emily Sena, Kristie Sullivan, José Tarazona, Andrea Terron, Kris Thayer, Jan Turner, Jos Verbeek, Didier Verloo, Mathieu Vinken, Sean Watford, Paul Whaley, Daniele Wikoff, Kate Willett, Katya Tsaioun
ALTEX. Author manuscript; available in PMC 2022 Sep 12.
Published in final edited form as: ALTEX. 2022; 39(3): 499–518. Published online 2022 Mar 1. doi: 10.14573/altex.2202141
PMCID:
PMC9466297
ArticlePDF–1006K
8.
COVID-19 through Adverse Outcome Pathways: Building Networks to Better Understand the Disease – 3rd CIAO AOP Design Workshop
Laure-Alix Clerbaux, Núria Amigó, Maria João Amorim, Anna Bal-Price, Sofia Batista Leite, Anna Beronius, Gillina F. G. Bezemer, Ann-Charlotte Bostroem, Annamaria Carusi, Sandra Coecke, Rachel Concha, Evangelos P. Daskalopoulos, Francesca Debernardi, Eizleayne Edrosa, Steve W. Edwards, Julija Filipovska, Natàlia Garcia-Reyero, Felicity N. E. Gavins, Sabina Halappanavar, Alan J. Hargreaves, Helena T. Hogberg, Mylène T. Huynh, Daniel Jacobson, Jonathan Josephs-Spaulding, Young Jun Kim, Hyun Joon Kong, Catharine E. Krebs, Ann Lam, Brigitte Landesmann, Adrienne Racanelli Layton, Yong Oh Lee, Donna S. Macmillan, Alberto Mantovani, Luigi Margiotta-Casaluci, Marvin Martens, Rosalinde Masereeuw, Sally A. Mayasich, Liang Merlin Mei, Holly Mortensen, Amalia Munoz, Penny Nymark, Elan Ohayon, Joshi Manoj Ojasi, Alicia Paini, Nikolaos Parissis, Surat Parvatam, Francesca Pistollato, Magdalini Sachana, Jorid Birkelund Sørli, Kristie M. Sullivan, Jukka Sund, Shihori Tanabe, Katya Tsaioun, Mathieu Vinken, Laura Viviani, Jennifer Waspe, Catherine Willett, Clemens Wittwehr
ALTEX. Author manuscript; available in PMC 2023 Apr 3.
Published in final edited form as: ALTEX. 2022; 39(2): 322–335. Published online 2022 Jan 3. doi: 10.14573/altex.2112161
PMCID:
PMC10069302
ArticlePDF–1.5M
9.
U.S. Federal Agency Interests and Key Considerations for New Approach Methodologies for Nanomaterials
Elijah J. Petersen, Patricia Ceger, David G. Allen, Jayme Coyle, Raymond Derk, Natalia Garcia Reyero, John Gordon, Nicole Kleinstreuer, Joanna Matheson, Danielle McShan, Bryant C. Nelson, Anil K. Patri, Penelope Rice, Liying Rojanasakul, Abhilash Sasidharan, Louis Scarano, Xiaoqing Chang
ALTEX. Author manuscript; available in PMC 2022 May 18.
Published in final edited form as: ALTEX. 2022; 39(2): 183–206. Published online 2021 Dec 3. doi: 10.14573/altex.2105041
PMCID:
PMC9115850
ArticlePDF–217K
10.
Improving the Quality of Toxicology and Environmental Health Systematic Reviews: What Journal Editors Can Do
Paul Whaley, Bas J. Blaauboer, Jan Brozek, Elaine A. Cohen Hubal, Kaitlyn Hair, Sam Kacew, Thomas B. Knudsen, Carol F. Kwiatkowski, David T. Mellor, Andrew F. Olshan, Matthew J. Page, Andrew A. Rooney, Elizabeth G. Radke, Larissa Shamseer, Katya Tsaioun, Peter Tugwell, Daniele Wikoff, Tracey J. Woodruff
ALTEX. Author manuscript; available in PMC 2022 Sep 14.
Published in final edited form as: ALTEX. 2021; 38(3): 513–522. Published online 2021 Jun 22. doi: 10.14573/altex.2106111
PMCID:
PMC9472299
ArticlePDF–709K
11.
Grouping of UVCB Substances with New Approach Methodologies (NAMs) Data
John S. House, Fabian A. Grimm, William D. Klaren, Abigail Dalzell, Srikeerthana Kuchi, Shu-Dong Zhang, Klaus Lenz, Peter J. Boogaard, Hans B. Ketelslegers, Timothy W. Gant, Fred A. Wright, Ivan Rusyn
ALTEX. Author manuscript; available in PMC 2021 Feb 23.
Published in final edited form as: ALTEX. 2021; 38(1): 123–137. Published online 2020 Oct 9. doi: 10.14573/altex.2006262
PMCID:
PMC7900923
ArticlePDF–1.9M
12.
Internationalization of Read-Across as a Validated New Approach Method (NAM) for Regulatory Toxicology
Costanza Rovida, Tara Barton-Maclaren, Emilio Benfenati, Francesca Caloni, P. Charukeshi Chandrasekera, Christophe Chesné, Mark T. D. Cronin, Joop De Knecht, Daniel R. Dietrich, Sylvia E. Escher, Suzanne Fitzpatrick, Brenna Flannery, Matthias Herzler, Susanne Hougaard Bennekou, Bruno Hubesch, Hennicke Kamp, Jaffar Kisitu, Nicole Kleinstreuer, Simona Kovarich, Marcel Leist, Alexandra Maertens, Kerry Nugent, Giorgia Pallocca, Manuel Pastor, Grace Patlewicz, Manuela Pavan, Octavio Presgrave, Lena Smirnova, Michael Schwarz, Takashi Yamada, Thomas Hartung
ALTEX. Author manuscript; available in PMC 2022 Jun 16.
Published in final edited form as: ALTEX. 2020; 37(4): 579–606. Published online 2020 Apr 30. doi: 10.14573/altex.1912181
PMCID:
PMC9201788
ArticlePDF–1.6M
13.
Generalised Read-Across (GenRA): A workflow implemented into the EPA CompTox Chemicals Dashboard
George Helman, Imran Shah, Antony J. Williams, Jeff Edwards, Jeremy Dunne, Grace Patlewicz
ALTEX. Author manuscript; available in PMC 2020 Feb 4.
Published in final edited form as: ALTEX. 2019; 36(3): 462–465. Published online 2019 Feb 4. doi: 10.14573/altex.1811292
PMCID:
PMC6679759
ArticlePDF–1.7M
14.
Recommendation on test readiness criteria for new approach methods (NAM) in toxicology: exemplified for developmental neurotoxicity (DNT)
Anna Bal-Price, Helena T. Hogberg, Kevin M. Crofton, Mardas Daneshian, Rex E. FitzGerald, Ellen Fritsche, Tuula Heinonen, Susanne Hougaard Bennekou, Stefanie Klima, Aldert H. Piersma, Magdalini Sachana, Timothy J. Shafer, Andrea Terron, Florianne Monnet-Tschudi, Barbara Viviani, Tanja Waldmann, Remco H.S. Westerink, Martin F. Wilks, Hilda Witters, Marie-Gabrielle Zurich, Marcel Leist
ALTEX. Author manuscript; available in PMC 2019 Jun 3.
Published in final edited form as: ALTEX. 2018; 35(3): 306–352. Published online 2018 Feb 23. doi: 10.14573/altex.1712081
Correction in:
ALTEX. 2019; 36(3): 506.
PMCID:
PMC6545888
ArticlePDF–2.4M
15.
3S – Systematic, Systemic, and Systems Biology and Toxicology
Lena Smirnova, Nicole Kleinstreuer, Raffaella Corvi, Andre Levchenko, Suzanne C. Fitzpatrick, Thomas Hartung
ALTEX. Author manuscript; available in PMC 2019 Aug 16.
Published in final edited form as: ALTEX. 2018; 35(2): 139–162. doi: 10.14573/altex.1804051
PMCID:
PMC6696989
ArticlePDF–414K
16.
Ex Vivo Model Unravelling Cell Distribution Effect in Hydrogels for Cartilage Repair
Vivian H. M. Mouser, Noël M. M. Dautzenberg, Riccardo Levato, Mattie H. P. van Rijen, Wouter J. A. Dhert, Jos Malda, Debby Gawlitta
ALTEX. Author manuscript; available in PMC 2020 Oct 16.
Published in final edited form as: ALTEX. 2018 Jan 1; 35(1): 65–76. Published online 2017 Sep 8. doi: 10.14573/altex.1704171
PMCID:
PMC7116182
ArticlePDF–2.1M
17.
Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups
Weihsueh A. Chiu, Kathryn Z. Guyton, Matthew T. Martin, David M. Reif, Ivan Rusyn
ALTEX. Author manuscript; available in PMC 2018 Jan 26.
Published in final edited form as: ALTEX. 2018; 35(1): 51–64. Published online 2017 Jul 24. doi: 10.14573/altex.1703231
PMCID:
PMC5783793
ArticlePDF–819K
18.
Advancing Toxicology Research Using In Vivo High Throughput Toxicology with Small Fish Models
Antonio Planchart, Carolyn J. Mattingly, David Allen, Patricia Ceger, Warren Casey, David Hinton, Jyotshna Kanungo, Seth W. Kullman, Tamara Tal, Maria Bondesson, Shawn M. Burgess, Con Sullivan, Carol Kim, Mamta Behl, Stephanie Padilla, David M. Reif, Robert L. Tanguay, Jon Hamm
ALTEX. Author manuscript; available in PMC 2017 Jan 27.
Published in final edited form as: ALTEX. 2016; 33(4): 435–452. Published online 2016 Jun 21. doi: 10.14573/altex.1601281
PMCID:
PMC5270630
ArticlePDF–418K
19.
Biology-inspired Microphysiological System Approaches to Solve the Prediction Dilemma of Substance Testing
Uwe Marx, Tommy B. Andersson, Anthony Bahinski, Mario Beilmann, Sonja Beken, Flemming R. Cassee, Murat Cirit, Mardas Daneshian, Susan Fitzpatrick, Olivier Frey, Claudia Gaertner, Christoph Giese, Linda Griffith, Thomas Hartung, Minne B. Heringa, Julia Hoeng, Wim H. de Jong, Hajime Kojima, Jochen Kuehnl, Andreas Luch, Ilka Maschmeyer, Dmitry Sakharov, Adrienne J. A. M. Sips, Thomas Steger-Hartmann, Danilo A. Tagle, Alexander Tonevitsky, Tewes Tralau, Sergej Tsyb, Anja van de Stolpe, Rob Vandebriel, Paul Vulto, Jufeng Wang, Joachim Wiest, Marleen Rodenburg, Adrian Roth
ALTEX. Author manuscript; available in PMC 2017 Apr 19.
Published in final edited form as: ALTEX. 2016; 33(3): 272–321. Published online 2016 May 15. doi: 10.14573/altex.1603161
PMCID:
PMC5396467
ArticlePDF–3.3M
20.
Analysis of Publically Available Skin Sensitization Data from REACH Registrations 2008–2014
Thomas Luechtefeld, Alexandra Maertens, Daniel P. Russo, Costanza Rovida, Hao Zhu, Thomas Hartung
ALTEX. Author manuscript; available in PMC 2017 Aug 7.
Published in final edited form as: ALTEX. 2016; 33(2): 135–148. Published online 2016 Feb 11. doi: 10.14573/altex.1510055
PMCID:
PMC5546098
ArticlePDF–1.5M

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  • RecName: Full=Host cell factor 1; Short=HCF; Short=HCF-1; AltName: Full=C1 facto...
    RecName: Full=Host cell factor 1; Short=HCF; Short=HCF-1; AltName: Full=C1 factor; AltName: Full=CFF; AltName: Full=VCAF; AltName: Full=VP16 accessory protein; Contains: RecName: Full=HCF N-terminal chain 1; Contains: RecName: Full=HCF N-terminal chain 2; Contains: RecName: Full=HCF N-terminal chain 3; Contains: RecName: Full=HCF N-terminal chain 4; Contains: RecName: Full=HCF N-terminal chain 5; Contains: RecName: Full=HCF N-terminal chain 6; Contains: RecName: Full=HCF C-terminal chain 1; Contains: RecName: Full=HCF C-terminal chain 2; Contains: RecName: Full=HCF C-terminal chain 3; Contains: RecName: Full=HCF C-terminal chain 4; Contains: RecName: Full=HCF C-terminal chain 5; Contains: RecName: Full=HCF C-terminal chain 6
    gi|160332311|sp|P51610.2|HCFC1_HUMA
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