Definition

T acute lymphoblastic leukemia in which the blasts have unique immunophenotypic and genetic characteristics suggesting only limited early T-cell differentiation. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVEarly T cell progenitor acute lymphoblastic leukemia

Hematologic disorder
- Hematologic neoplasm
  - Leukemia
    - Acute leukemia
      - Acute lymphoid leukemia
        T-cell acute lymphoblastic leukemia
        Early T cell progenitor acute lymphoblastic leukemia

Recent clinical studies

Diagnosis

Homoharringtonine synergizes with venetoclax in early T cell progenitor acute lymphoblastic leukemia: Bench and bed.

Suo S, Sun S, Nguyen LXT, Qian J, Li F, Zhao D, Yu W, Lou Y, Zhu H, Tong H, Yang M, Huang X, Zhao S, Qiao J, Liang C, Wang H, Zhang Y, Zhang X, Hoang DH, Chen F, Kang H, Valerio M, Sun J, Ghoda L, Li L, Marcucci G, Zhang B, Jin J
Med 2024 Dec 13;5(12):1510-1524.e4. Epub 2024 Aug 15 doi: 10.1016/j.medj.2024.07.018. PMID: 39151422

See all (1)

Therapy

Homoharringtonine synergizes with venetoclax in early T cell progenitor acute lymphoblastic leukemia: Bench and bed.

Suo S, Sun S, Nguyen LXT, Qian J, Li F, Zhao D, Yu W, Lou Y, Zhu H, Tong H, Yang M, Huang X, Zhao S, Qiao J, Liang C, Wang H, Zhang Y, Zhang X, Hoang DH, Chen F, Kang H, Valerio M, Sun J, Ghoda L, Li L, Marcucci G, Zhang B, Jin J
Med 2024 Dec 13;5(12):1510-1524.e4. Epub 2024 Aug 15 doi: 10.1016/j.medj.2024.07.018. PMID: 39151422

See all (1)

Prognosis

Homoharringtonine synergizes with venetoclax in early T cell progenitor acute lymphoblastic leukemia: Bench and bed.

Suo S, Sun S, Nguyen LXT, Qian J, Li F, Zhao D, Yu W, Lou Y, Zhu H, Tong H, Yang M, Huang X, Zhao S, Qiao J, Liang C, Wang H, Zhang Y, Zhang X, Hoang DH, Chen F, Kang H, Valerio M, Sun J, Ghoda L, Li L, Marcucci G, Zhang B, Jin J
Med 2024 Dec 13;5(12):1510-1524.e4. Epub 2024 Aug 15 doi: 10.1016/j.medj.2024.07.018. PMID: 39151422

See all (1)

Synonym:	Early T Acute Lymphoblastic Leukemia

Monarch Initiative:	MONDO:0100291

MedGen

National Center for Biotechnology Information

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Early T cell progenitor acute lymphoblastic leukemia

Definition

Term Hierarchy

Recent clinical studies

Diagnosis

Therapy

Prognosis

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