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Abnormal cellular immune system morphology

MedGen UID:
869190
Concept ID:
C4023612
Pathologic Function
Synonym: Abnormality of cellular immune system
 
HPO: HP:0010987

Definition

An abnormality of the morphology or counts of the cells that make up the immune system. [from HPO]

Professional guidelines

PubMed

Pardanani A
Am J Hematol 2021 Apr 1;96(4):508-525. Epub 2021 Feb 21 doi: 10.1002/ajh.26118. PMID: 33524167
Patnaik MM, Tefferi A
Am J Hematol 2021 Mar 1;96(3):379-394. Epub 2021 Jan 28 doi: 10.1002/ajh.26090. PMID: 33428785
Phillips J, Henderson AC
Am Fam Physician 2018 Sep 15;98(6):354-361. PMID: 30215915

Recent clinical studies

Etiology

Dinges SS, Amini K, Notarangelo LD, Delmonte OM
Immunol Rev 2024 Mar;322(1):178-211. Epub 2024 Jan 16 doi: 10.1111/imr.13306. PMID: 38228406Free PMC Article
Yamanaka K, Yamamoto O, Honda T
J Dermatol 2021 Jun;48(6):722-731. Epub 2021 Apr 22 doi: 10.1111/1346-8138.15913. PMID: 33886133
Gan RWC, Moustafa A, Turner K, Knight L
Acta Otolaryngol 2021 Jan;141(1):85-88. Epub 2020 Oct 14 doi: 10.1080/00016489.2020.1821246. PMID: 33393421
Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral D, Van de Water J
Ann N Y Acad Sci 2007 Jun;1107:79-91. doi: 10.1196/annals.1381.009. PMID: 17804535
Kuhn EM, Therman E
Cancer Genet Cytogenet 1986 May;22(1):1-18. doi: 10.1016/0165-4608(86)90132-9. PMID: 3513946

Diagnosis

Jung R, Trivedi CM
Circ Res 2024 Jun 21;135(1):159-173. Epub 2024 Jun 20 doi: 10.1161/CIRCRESAHA.124.323181. PMID: 38900856Free PMC Article
Dinges SS, Amini K, Notarangelo LD, Delmonte OM
Immunol Rev 2024 Mar;322(1):178-211. Epub 2024 Jan 16 doi: 10.1111/imr.13306. PMID: 38228406Free PMC Article
Devonshire AL, Makhija M
Allergy Asthma Proc 2019 Nov 1;40(6):465-469. doi: 10.2500/aap.2019.40.4273. PMID: 31690396Free PMC Article
Dispenzieri A, Kourelis T, Buadi F
Hematol Oncol Clin North Am 2018 Feb;32(1):119-139. doi: 10.1016/j.hoc.2017.09.010. PMID: 29157614
Askin DF, Young S
Neonatal Netw 2001 Dec;20(8):7-13. doi: 10.1891/0730-0832.20.8.7. PMID: 12144107

Therapy

Li W, Lin A, Qi L, Lv X, Yan S, Xue J, Mu N
Front Immunol 2023;14:1128301. Epub 2023 Apr 17 doi: 10.3389/fimmu.2023.1128301. PMID: 37138868Free PMC Article
Liu S, Galat V, Galat Y, Lee YKA, Wainwright D, Wu J
J Hematol Oncol 2021 Jan 6;14(1):7. doi: 10.1186/s13045-020-01014-w. PMID: 33407739Free PMC Article
Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, Xu Y, Wu Q, Guo X, Nie J, Lu B, Huang B, Xian H, Wang X, Wu Q, Zeng J, Chai C, Zhang M, Lin Y, Zhang L, Zhao S, Tong Y, Zeng L, Gu X, Chen ZG, Yi S, Zhang T, Delfouneso D, Zhang Y, Nutt SL, Lew AM, Lu L, Bai F, Xia H, Wen Z, Zhang Y
Cell 2020 Dec 23;183(7):1867-1883.e26. Epub 2020 Nov 27 doi: 10.1016/j.cell.2020.10.048. PMID: 33248023
Dispenzieri A, Kourelis T, Buadi F
Hematol Oncol Clin North Am 2018 Feb;32(1):119-139. doi: 10.1016/j.hoc.2017.09.010. PMID: 29157614
Kaplan AP, Giménez-Arnau AM, Saini SS
Allergy 2017 Apr;72(4):519-533. Epub 2017 Jan 4 doi: 10.1111/all.13083. PMID: 27861988Free PMC Article

Prognosis

Illouz T, Biragyn A, Frenkel-Morgenstern M, Weissberg O, Gorohovski A, Merzon E, Green I, Iulita F, Flores-Aguilar L, Dierssen M, De Toma I, Lifshitz H, Antonarakis SE, Yu E, Herault Y, Potier MC, Botté A, Roper R, Sredni B, Sarid R, London J, Mobley W, Strydom A, Okun E
Neuromolecular Med 2021 Dec;23(4):561-571. Epub 2021 Mar 4 doi: 10.1007/s12017-021-08651-5. PMID: 33660221Free PMC Article
Wagner J, Rapsomaniki MA, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, Rees M, Ramaswamy A, Muenst S, Soysal SD, Jacobs A, Windhager J, Silina K, van den Broek M, Dedes KJ, Rodríguez Martínez M, Weber WP, Bodenmiller B
Cell 2019 May 16;177(5):1330-1345.e18. Epub 2019 Apr 11 doi: 10.1016/j.cell.2019.03.005. PMID: 30982598Free PMC Article
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Bonassi S, El-Zein R, Bolognesi C, Fenech M
Mutagenesis 2011 Jan;26(1):93-100. doi: 10.1093/mutage/geq075. PMID: 21164188
Nowell PC
Hum Pathol 1981 Jun;12(6):522-30. doi: 10.1016/s0046-8177(81)80066-4. PMID: 7275093

Clinical prediction guides

Boussard C, Delage L, Gajardo T, Kauskot A, Batignes M, Goudin N, Stolzenberg MC, Brunaud C, Panikulam P, Riller Q, Moya-Nilges M, Solarz J, Repérant C, Durel B, Bordet JC, Pellé O, Lebreton C, Magérus A, Pirabakaran V, Vargas P, Dupichaud S, Jeanpierre M, Vinit A, Zarhrate M, Masson C, Aladjidi N, Arkwright PD, Bader-Meunier B, Baron Joly S, Benadiba J, Bernard E, Berrebi D, Bodemer C, Castelle M, Charbit-Henrion F, Chbihi M, Debray A, Drabent P, Fraitag S, Hié M, Landman-Parker J, Lhermitte L, Moshous D, Rohrlich P, Ruemmele F, Welfringer-Morin A, Tusseau M, Belot A, Cerf-Bensussan N, Roelens M, Picard C, Neven B, Fischer A, Callebaut I, Ménager M, Sepulveda FE, Adam F, Rieux-Laucat F
Blood 2023 Jun 1;141(22):2713-2726. doi: 10.1182/blood.2022018486. PMID: 36952639
Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral D, Van de Water J
Ann N Y Acad Sci 2007 Jun;1107:79-91. doi: 10.1196/annals.1381.009. PMID: 17804535
Popovic PJ, Zeh HJ 3rd, Ochoa JB
J Nutr 2007 Jun;137(6 Suppl 2):1681S-1686S. doi: 10.1093/jn/137.6.1681S. PMID: 17513447
Tsubata T
Autoimmunity 2005 Aug;38(5):331-7. doi: 10.1080/08916930500123959. PMID: 16240466
Nowell PC
Hum Pathol 1981 Jun;12(6):522-30. doi: 10.1016/s0046-8177(81)80066-4. PMID: 7275093

Recent systematic reviews

Fukasawa T, Yoshizaki-Ogawa A, Enomoto A, Yamashita T, Miyagawa K, Sato S, Yoshizaki A
Immunol Med 2024 Sep;47(3):118-129. Epub 2024 May 31 doi: 10.1080/25785826.2024.2360690. PMID: 38818750
Terri M, Trionfetti F, Montaldo C, Cordani M, Tripodi M, Lopez-Cabrera M, Strippoli R
Front Immunol 2021;12:607204. Epub 2021 Mar 29 doi: 10.3389/fimmu.2021.607204. PMID: 33854496Free PMC Article
Scappaticcio L, Maiorino MI, Maio A, Esposito K, Bellastella G
Clin Endocrinol (Oxf) 2021 Mar;94(3):473-483. Epub 2020 Sep 1 doi: 10.1111/cen.14313. PMID: 32799342
Mostmans Y, Cutolo M, Giddelo C, Decuman S, Melsens K, Declercq H, Vandecasteele E, De Keyser F, Distler O, Gutermuth J, Smith V
Autoimmun Rev 2017 Aug;16(8):774-786. Epub 2017 May 29 doi: 10.1016/j.autrev.2017.05.024. PMID: 28572048
Viswanath B, Jose SP, Squassina A, Thirthalli J, Purushottam M, Mukherjee O, Vladimirov V, Patrinos GP, Del Zompo M, Jain S
J Affect Disord 2015 Sep 15;184:36-50. Epub 2015 May 28 doi: 10.1016/j.jad.2015.05.037. PMID: 26070045

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