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Abnormality of the gastrointestinal tract

MedGen UID:
892790
Concept ID:
C4023588
Anatomical Abnormality
Synonyms: Abnormality of the GI tract; alimentary system disease; digestive disease; Digestive system disease; digestive system disease; digestive system disease or disorder; digestive system disorder; disease of digestive system; disease or disorder of digestive system; disorder of digestive system; gastroenterological system disease; gastroenterological system disorder; gastroenteropathy; Gastrointestinal disease; gastrointestinal disease; gastrointestinal disorder; gastrointestinal system disease; gastrointestinal system disorder; git disease; stomach or intestinal disorder
 
HPO: HP:0011024
Monarch Initiative: MONDO:0004335

Definition

An abnormality of the gastrointestinal tract. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of the gastrointestinal tract

Professional guidelines

PubMed

Popa DE, Caliţa M, Pîrlog MC, Constantin C, Popp CG, Gheonea DI
Rom J Morphol Embryol 2021 Apr-Jun;62(2):395-400. doi: 10.47162/RJME.62.2.05. PMID: 35024727Free PMC Article

Recent clinical studies

Etiology

Tonni G, Koçak Ç, Grisolia G, Rizzo G, Araujo Júnior E, Werner H, Ruano R, Sepulveda W, Bonasoni MP, Lituania M; “International Perinatology Research Group (IPRG)”
Fetal Pediatr Pathol 2023 Aug;42(4):651-674. Epub 2023 May 17 doi: 10.1080/15513815.2023.2206905. PMID: 37195727
Morita A, Tagawa M, Imagawa K, Endo M, Takada H
Pediatr Int 2022 Jan;64(1):e15066. doi: 10.1111/ped.15066. PMID: 35484904
Solomon BD
Am J Med Genet C Semin Med Genet 2018 Dec;178(4):440-446. doi: 10.1002/ajmg.c.31664. PMID: 30580478
Dogan DG, Dogan M, Aslan M, Menekse E, Yakinci C
Genet Couns 2010;21(4):359-62. PMID: 21290964
Ruiz-Moreno F, Gerdo-Ceballo A, Lozano-Saldivar G
Dis Colon Rectum 1980 Jul-Aug;23(5):306-7. doi: 10.1007/BF02586833. PMID: 7398504

Diagnosis

Zhang W, Chen J
Prenat Diagn 2022 Apr;42(4):482-483. Epub 2022 Jan 31 doi: 10.1002/pd.6100. PMID: 35037266
Furman MS, Connolly SA, Brown SD, Callahan MJ
Pediatr Radiol 2021 Dec;51(13):2461-2469. Epub 2021 Aug 5 doi: 10.1007/s00247-021-05155-z. PMID: 34351495
Strychowsky JE, Rahbar R
Semin Pediatr Surg 2016 Jun;25(3):128-31. Epub 2016 Feb 21 doi: 10.1053/j.sempedsurg.2016.02.005. PMID: 27301597
Butler Tjaden NE, Trainor PA
Transl Res 2013 Jul;162(1):1-15. Epub 2013 Mar 22 doi: 10.1016/j.trsl.2013.03.001. PMID: 23528997Free PMC Article
Barnewolt CE
Semin Roentgenol 2004 Apr;39(2):263-81. doi: 10.1053/j.ro.2004.02.002. PMID: 15143689

Therapy

Society for Maternal-Fetal Medicine (SMFM), Gandhi M, Rac MWF, McKinney J
Am J Obstet Gynecol 2019 Dec;221(6):B16-B18. doi: 10.1016/j.ajog.2019.09.024. PMID: 31787159
Israelyan N, Del Colle A, Li Z, Park Y, Xing A, Jacobsen JPR, Luna RA, Jensen DD, Madra M, Saurman V, Rahim R, Latorre R, Law K, Carson W, Bunnett NW, Caron MG, Margolis KG
Gastroenterology 2019 Aug;157(2):507-521.e4. Epub 2019 May 7 doi: 10.1053/j.gastro.2019.04.022. PMID: 31071306Free PMC Article
Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R
Microbiome 2017 Jan 23;5(1):10. doi: 10.1186/s40168-016-0225-7. PMID: 28122648Free PMC Article
Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK
Cell 2013 Dec 19;155(7):1451-63. Epub 2013 Dec 5 doi: 10.1016/j.cell.2013.11.024. PMID: 24315484Free PMC Article
Holecek M
JPEN J Parenter Enteral Nutr 2013 Sep;37(5):607-16. Epub 2012 Sep 18 doi: 10.1177/0148607112460682. PMID: 22990615

Prognosis

Morita A, Tagawa M, Imagawa K, Endo M, Takada H
Pediatr Int 2022 Jan;64(1):e15066. doi: 10.1111/ped.15066. PMID: 35484904
Ludwig K, De Bartolo D, Salerno A, Ingravallo G, Cazzato G, Giacometti C, Dall'Igna P
Pathologica 2022 Feb;114(1):40-54. doi: 10.32074/1591-951X-553. PMID: 35212315Free PMC Article
Leboulanger N, Garabédian EN
Orphanet J Rare Dis 2011 Dec 7;6:81. doi: 10.1186/1750-1172-6-81. PMID: 22151899Free PMC Article
Dogan DG, Dogan M, Aslan M, Menekse E, Yakinci C
Genet Couns 2010;21(4):359-62. PMID: 21290964
Quinn D, Shannon LF
Neonatal Netw 2000 Sep;19(6):41-4. doi: 10.1891/0730-0832.19.6.41. PMID: 11949119

Clinical prediction guides

Schierz IAM, Piro E, Giuffrè M, Pinello G, Angelini A, Antona V, Cimador M, Corsello G
J Matern Fetal Neonatal Med 2022 Dec;35(23):4513-4520. Epub 2020 Dec 1 doi: 10.1080/14767058.2020.1854213. PMID: 36062518
Dworschak GC, Reutter HM, Ludwig M
Orphanet J Rare Dis 2021 Apr 9;16(1):167. doi: 10.1186/s13023-021-01799-0. PMID: 33836786Free PMC Article
Ambartsumyan L, Smith C, Kapur RP
Pediatr Dev Pathol 2020 Jan-Feb;23(1):8-22. Epub 2019 Dec 2 doi: 10.1177/1093526619892351. PMID: 31791203
Gosain A, Brinkman AS
Curr Opin Pediatr 2015 Jun;27(3):364-9. doi: 10.1097/MOP.0000000000000210. PMID: 25944307Free PMC Article
Levitt MA, Peña A
Orphanet J Rare Dis 2007 Jul 26;2:33. doi: 10.1186/1750-1172-2-33. PMID: 17651510Free PMC Article

Recent systematic reviews

Zdrhova L, Bitnar P, Balihar K, Kolar P, Madle K, Martinek M, Pandolfino JE, Martinek J
Dysphagia 2023 Apr;38(2):609-621. Epub 2022 Jul 16 doi: 10.1007/s00455-022-10494-6. PMID: 35842548Free PMC Article
Gefen R, Garoufalia Z, Zhou P, Watson K, Emile SH, Wexner SD
Tech Coloproctol 2022 Nov;26(11):863-874. Epub 2022 Aug 1 doi: 10.1007/s10151-022-02656-3. PMID: 35915291
Thwaites PA, Gibson PR, Burgell RE
J Gastroenterol Hepatol 2022 Sep;37(9):1693-1709. Epub 2022 Jul 20 doi: 10.1111/jgh.15927. PMID: 35750466Free PMC Article
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Pandolfino JE, Gawron AJ
JAMA 2015 May 12;313(18):1841-52. doi: 10.1001/jama.2015.2996. PMID: 25965233

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