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Early onset Alzheimer disease with behavioral disturbance

MedGen UID:
784944
Concept ID:
C3697680
Mental or Behavioral Dysfunction
Synonyms: Early onset Alzheimer's disease with behavioral disturbance; Early onset Alzheimers disease with behavioral disturbance
SNOMED CT: Early onset Alzheimer's disease with behavioral disturbance (105421000119105); Early onset Alzheimers disease with behavioral disturbance (105421000119105); Early onset Alzheimer disease with behavioral disturbance (105421000119105)

Professional guidelines

PubMed

Weisbrod N
Neurotherapeutics 2022 Jan;19(1):143-151. Epub 2022 Jan 26 doi: 10.1007/s13311-021-01171-x. PMID: 35080735Free PMC Article
Frederiksen KS, Cooper C, Frisoni GB, Frölich L, Georges J, Kramberger MG, Nilsson C, Passmore P, Mantoan Ritter L, Religa D, Schmidt R, Stefanova E, Verdelho A, Vandenbulcke M, Winblad B, Waldemar G
Eur J Neurol 2020 Oct;27(10):1805-1820. Epub 2020 Jul 26 doi: 10.1111/ene.14412. PMID: 32713125Free PMC Article
Matsunaga S, Kishi T, Nomura I, Sakuma K, Okuya M, Ikuta T, Iwata N
Expert Opin Drug Saf 2018 Oct;17(10):1053-1061. Epub 2018 Sep 26 doi: 10.1080/14740338.2018.1524870. PMID: 30222469

Recent clinical studies

Etiology

Polsinelli AJ, Apostolova LG
Continuum (Minneap Minn) 2022 Jun 1;28(3):676-701. doi: 10.1212/CON.0000000000001082. PMID: 35678398Free PMC Article
Deardorff WJ, Grossberg GT
Handb Clin Neurol 2019;165:5-32. doi: 10.1016/B978-0-444-64012-3.00002-2. PMID: 31727229
Irwin MR, Vitiello MV
Lancet Neurol 2019 Mar;18(3):296-306. Epub 2019 Jan 17 doi: 10.1016/S1474-4422(18)30450-2. PMID: 30661858
Hu X, Wang T, Jin F
Sci China Life Sci 2016 Oct;59(10):1006-1023. Epub 2016 Aug 26 doi: 10.1007/s11427-016-5083-9. PMID: 27566465
Peter-Derex L, Yammine P, Bastuji H, Croisile B
Sleep Med Rev 2015 Feb;19:29-38. Epub 2014 Apr 3 doi: 10.1016/j.smrv.2014.03.007. PMID: 24846773

Diagnosis

Chen Y, Al-Nusaif M, Li S, Tan X, Yang H, Cai H, Le W
Front Med 2024 Jun;18(3):446-464. Epub 2024 May 21 doi: 10.1007/s11684-023-1047-1. PMID: 38769282Free PMC Article
Polsinelli AJ, Apostolova LG
Continuum (Minneap Minn) 2022 Jun 1;28(3):676-701. doi: 10.1212/CON.0000000000001082. PMID: 35678398Free PMC Article
Deardorff WJ, Grossberg GT
Handb Clin Neurol 2019;165:5-32. doi: 10.1016/B978-0-444-64012-3.00002-2. PMID: 31727229
Irwin MR, Vitiello MV
Lancet Neurol 2019 Mar;18(3):296-306. Epub 2019 Jan 17 doi: 10.1016/S1474-4422(18)30450-2. PMID: 30661858
Peter-Derex L, Yammine P, Bastuji H, Croisile B
Sleep Med Rev 2015 Feb;19:29-38. Epub 2014 Apr 3 doi: 10.1016/j.smrv.2014.03.007. PMID: 24846773

Therapy

Megur A, Baltriukienė D, Bukelskienė V, Burokas A
Nutrients 2020 Dec 24;13(1) doi: 10.3390/nu13010037. PMID: 33374235Free PMC Article
Deardorff WJ, Grossberg GT
Handb Clin Neurol 2019;165:5-32. doi: 10.1016/B978-0-444-64012-3.00002-2. PMID: 31727229
Matsunaga S, Kishi T, Nomura I, Sakuma K, Okuya M, Ikuta T, Iwata N
Expert Opin Drug Saf 2018 Oct;17(10):1053-1061. Epub 2018 Sep 26 doi: 10.1080/14740338.2018.1524870. PMID: 30222469
Kishi T, Matsunaga S, Oya K, Nomura I, Ikuta T, Iwata N
J Alzheimers Dis 2017;60(2):401-425. doi: 10.3233/JAD-170424. PMID: 28922160
Hu X, Wang T, Jin F
Sci China Life Sci 2016 Oct;59(10):1006-1023. Epub 2016 Aug 26 doi: 10.1007/s11427-016-5083-9. PMID: 27566465

Prognosis

Chen Y, Al-Nusaif M, Li S, Tan X, Yang H, Cai H, Le W
Front Med 2024 Jun;18(3):446-464. Epub 2024 May 21 doi: 10.1007/s11684-023-1047-1. PMID: 38769282Free PMC Article
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W Jr, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, Tosto G, Traykov L, Tremolizzo L, Tybjærg-Hansen A, Uitterlinden A, Ullgren A, Ulstein I, Valero S, Valladares O, Broeckhoven CV, Vance J, Vardarajan BN, van der Lugt A, Dongen JV, van Rooij J, van Swieten J, Vandenberghe R, Verhey F, Vidal JS, Vogelgsang J, Vyhnalek M, Wagner M, Wallon D, Wang LS, Wang R, Weinhold L, Wiltfang J, Windle G, Woods B, Yannakoulia M, Zare H, Zhao Y, Zhang X, Zhu C, Zulaica M; EADB; GR@ACE; DEGESCO; EADI; GERAD; Demgene; FinnGen; ADGC; CHARGE, Farrer LA, Psaty BM, Ghanbari M, Raj T, Sachdev P, Mather K, Jessen F, Ikram MA, de Mendonça A, Hort J, Tsolaki M, Pericak-Vance MA, Amouyel P, Williams J, Frikke-Schmidt R, Clarimon J, Deleuze JF, Rossi G, Seshadri S, Andreassen OA, Ingelsson M, Hiltunen M, Sleegers K, Schellenberg GD, van Duijn CM, Sims R, van der Flier WM, Ruiz A, Ramirez A, Lambert JC
Nat Genet 2022 Apr;54(4):412-436. Epub 2022 Apr 4 doi: 10.1038/s41588-022-01024-z. PMID: 35379992Free PMC Article
Weisbrod N
Neurotherapeutics 2022 Jan;19(1):143-151. Epub 2022 Jan 26 doi: 10.1007/s13311-021-01171-x. PMID: 35080735Free PMC Article
Irwin MR, Vitiello MV
Lancet Neurol 2019 Mar;18(3):296-306. Epub 2019 Jan 17 doi: 10.1016/S1474-4422(18)30450-2. PMID: 30661858
Matsunaga S, Kishi T, Nomura I, Sakuma K, Okuya M, Ikuta T, Iwata N
Expert Opin Drug Saf 2018 Oct;17(10):1053-1061. Epub 2018 Sep 26 doi: 10.1080/14740338.2018.1524870. PMID: 30222469

Clinical prediction guides

Chen Y, Al-Nusaif M, Li S, Tan X, Yang H, Cai H, Le W
Front Med 2024 Jun;18(3):446-464. Epub 2024 May 21 doi: 10.1007/s11684-023-1047-1. PMID: 38769282Free PMC Article
Zhang Y, Ren R, Yang L, Zhang H, Shi Y, Okhravi HR, Vitiello MV, Sanford LD, Tang X
Transl Psychiatry 2022 Apr 1;12(1):136. doi: 10.1038/s41398-022-01897-y. PMID: 35365609Free PMC Article
Kim B, Noh GO, Kim K
BMC Geriatr 2021 Mar 5;21(1):160. doi: 10.1186/s12877-021-02109-w. PMID: 33663416Free PMC Article
Shi L, Chen SJ, Ma MY, Bao YP, Han Y, Wang YM, Shi J, Vitiello MV, Lu L
Sleep Med Rev 2018 Aug;40:4-16. Epub 2017 Jul 6 doi: 10.1016/j.smrv.2017.06.010. PMID: 28890168
Peter-Derex L, Yammine P, Bastuji H, Croisile B
Sleep Med Rev 2015 Feb;19:29-38. Epub 2014 Apr 3 doi: 10.1016/j.smrv.2014.03.007. PMID: 24846773

Recent systematic reviews

Zhang Y, Ren R, Yang L, Zhang H, Shi Y, Okhravi HR, Vitiello MV, Sanford LD, Tang X
Transl Psychiatry 2022 Apr 1;12(1):136. doi: 10.1038/s41398-022-01897-y. PMID: 35365609Free PMC Article
Bubu OM, Andrade AG, Umasabor-Bubu OQ, Hogan MM, Turner AD, de Leon MJ, Ogedegbe G, Ayappa I, Jean-Louis G G, Jackson ML, Varga AW, Osorio RS
Sleep Med Rev 2020 Apr;50:101250. Epub 2019 Dec 12 doi: 10.1016/j.smrv.2019.101250. PMID: 31881487Free PMC Article
Matsunaga S, Kishi T, Nomura I, Sakuma K, Okuya M, Ikuta T, Iwata N
Expert Opin Drug Saf 2018 Oct;17(10):1053-1061. Epub 2018 Sep 26 doi: 10.1080/14740338.2018.1524870. PMID: 30222469
Kishi T, Matsunaga S, Oya K, Nomura I, Ikuta T, Iwata N
J Alzheimers Dis 2017;60(2):401-425. doi: 10.3233/JAD-170424. PMID: 28922160
Abraha I, Rimland JM, Trotta FM, Dell'Aquila G, Cruz-Jentoft A, Petrovic M, Gudmundsson A, Soiza R, O'Mahony D, Guaita A, Cherubini A
BMJ Open 2017 Mar 16;7(3):e012759. doi: 10.1136/bmjopen-2016-012759. PMID: 28302633Free PMC Article

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