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Lung cancer, protection against

MedGen UID:
409703
•Concept ID:
C1968897
•
Finding
Synonym: LUNG CANCER, PROTECTION AGAINST
 
OMIM®: 122720; 211980; 601763

Professional guidelines

PubMed

The Role of Polyphenol (Flavonoids) Compounds in the Treatment of Cancer Cells.
Hazafa A, Rehman KU, Jahan N, Jabeen Z
Nutr Cancer 2020;72(3):386-397. Epub 2019 Jul 9 doi: 10.1080/01635581.2019.1637006. PMID: 31287738
Quercetin: a natural compound for ovarian cancer treatment.
Shafabakhsh R, Asemi Z
J Ovarian Res 2019 Jun 15;12(1):55. doi: 10.1186/s13048-019-0530-4. PMID: 31202269Free PMC Article
Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.
Annane D, Pastores SM, Rochwerg B, Arlt W, Balk RA, Beishuizen A, Briegel J, Carcillo J, Christ-Crain M, Cooper MS, Marik PE, Umberto Meduri G, Olsen KM, Rodgers S, Russell JA, Van den Berghe G
Intensive Care Med 2017 Dec;43(12):1751-1763. Epub 2017 Sep 21 doi: 10.1007/s00134-017-4919-5. PMID: 28940011

Recent clinical studies

Etiology

Assessing the causal relationship between 731 immunophenotypes and the risk of lung cancer: a bidirectional mendelian randomization study.
Xu M, Li C, Xiang L, Chen S, Chen L, Ling G, Hu Y, Yang L, Yuan X, Xia X, Zhang H
BMC Cancer 2024 Feb 26;24(1):270. doi: 10.1186/s12885-024-12014-1. PMID: 38408977Free PMC Article
The Role of Polyphenol (Flavonoids) Compounds in the Treatment of Cancer Cells.
Hazafa A, Rehman KU, Jahan N, Jabeen Z
Nutr Cancer 2020;72(3):386-397. Epub 2019 Jul 9 doi: 10.1080/01635581.2019.1637006. PMID: 31287738
Nitroxides as Antioxidants and Anticancer Drugs.
Lewandowski M, Gwozdzinski K
Int J Mol Sci 2017 Nov 22;18(11) doi: 10.3390/ijms18112490. PMID: 29165366Free PMC Article
Comparison of the protective effects of truncated bFGF and native bFGF against murine lung carcinoma.
Luo Z, Peng X, Shi H, Gong C, Qian Z, Yang L
Int J Mol Med 2011 Jul;28(1):3-8. Epub 2011 Apr 14 doi: 10.3892/ijmm.2011.676. PMID: 21503566
Micronutrients and cancer.
Johnson IT
Proc Nutr Soc 2004 Nov;63(4):587-95. doi: 10.1079/pns2004389. PMID: 15831131

Diagnosis

The Minderoo-Monaco Commission on Plastics and Human Health.
Landrigan PJ, Raps H, Cropper M, Bald C, Brunner M, Canonizado EM, Charles D, Chiles TC, Donohue MJ, Enck J, Fenichel P, Fleming LE, Ferrier-Pages C, Fordham R, Gozt A, Griffin C, Hahn ME, Haryanto B, Hixson R, Ianelli H, James BD, Kumar P, Laborde A, Law KL, Martin K, Mu J, Mulders Y, Mustapha A, Niu J, Pahl S, Park Y, Pedrotti ML, Pitt JA, Ruchirawat M, Seewoo BJ, Spring M, Stegeman JJ, Suk W, Symeonides C, Takada H, Thompson RC, Vicini A, Wang Z, Whitman E, Wirth D, Wolff M, Yousuf AK, Dunlop S
Ann Glob Health 2023;89(1):23. Epub 2023 Mar 21 doi: 10.5334/aogh.4056. PMID: 36969097Free PMC Article
Lipocalin-2: Structure, function, distribution and role in metabolic disorders.
Jaberi SA, Cohen A, D'Souza C, Abdulrazzaq YM, Ojha S, Bastaki S, Adeghate EA
Biomed Pharmacother 2021 Oct;142:112002. Epub 2021 Aug 27 doi: 10.1016/j.biopha.2021.112002. PMID: 34463264
The Role of Polyphenol (Flavonoids) Compounds in the Treatment of Cancer Cells.
Hazafa A, Rehman KU, Jahan N, Jabeen Z
Nutr Cancer 2020;72(3):386-397. Epub 2019 Jul 9 doi: 10.1080/01635581.2019.1637006. PMID: 31287738
FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius E, Scheel CH, Mourão A, Buday K, Sato M, Wanninger J, Vignane T, Mohana V, Rehberg M, Flatley A, Schepers A, Kurz A, White D, Sauer M, Sattler M, Tate EW, Schmitz W, Schulze A, O'Donnell V, Proneth B, Popowicz GM, Pratt DA, Angeli JPF, Conrad M
Nature 2019 Nov;575(7784):693-698. Epub 2019 Oct 21 doi: 10.1038/s41586-019-1707-0. PMID: 31634899
Fisetin and Quercetin: Promising Flavonoids with Chemopreventive Potential.
Kashyap D, Garg VK, Tuli HS, Yerer MB, Sak K, Sharma AK, Kumar M, Aggarwal V, Sandhu SS
Biomolecules 2019 May 6;9(5) doi: 10.3390/biom9050174. PMID: 31064104Free PMC Article

Therapy

Adenosine in cancer immunotherapy: Taking off on a new plane.
Zhang C, Wang K, Wang H
Biochim Biophys Acta Rev Cancer 2023 Nov;1878(6):189005. Epub 2023 Oct 31 doi: 10.1016/j.bbcan.2023.189005. PMID: 37913941
Role of NRF2 in Lung Cancer.
Sánchez-Ortega M, Carrera AC, Garrido A
Cells 2021 Jul 24;10(8) doi: 10.3390/cells10081879. PMID: 34440648Free PMC Article
Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer.
Stading R, Gastelum G, Chu C, Jiang W, Moorthy B
Semin Cancer Biol 2021 Nov;76:3-16. Epub 2021 Jul 7 doi: 10.1016/j.semcancer.2021.07.001. PMID: 34242741Free PMC Article
Natural products: potential treatments for cisplatin-induced nephrotoxicity.
Fang CY, Lou DY, Zhou LQ, Wang JC, Yang B, He QJ, Wang JJ, Weng QJ
Acta Pharmacol Sin 2021 Dec;42(12):1951-1969. Epub 2021 Mar 9 doi: 10.1038/s41401-021-00620-9. PMID: 33750909Free PMC Article
Bovine milk-derived exosomes for drug delivery.
Munagala R, Aqil F, Jeyabalan J, Gupta RC
Cancer Lett 2016 Feb 1;371(1):48-61. Epub 2015 Nov 18 doi: 10.1016/j.canlet.2015.10.020. PMID: 26604130Free PMC Article

Prognosis

CTRP6 protects against ferroptosis to drive lung cancer progression and metastasis by destabilizing SOCS2 and augmenting the xCT/GPX4 pathway.
Cai S, Zhang B, Huang C, Deng Y, Wang C, Yang Y, Xiang Z, Ni Y, Wang Z, Wang L, Zhang B, Guo X, He J, Ma K, Yu Z
Cancer Lett 2023 Nov 28;579:216465. Epub 2023 Oct 29 doi: 10.1016/j.canlet.2023.216465. PMID: 38084702
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma.
Mastini C, Campisi M, Patrucco E, Mura G, Ferreira A, Costa C, Ambrogio C, Germena G, Martinengo C, Peola S, Mota I, Vissio E, Molinaro L, Arigoni M, Olivero M, Calogero R, Prokoph N, Tabbò F, Shoji B, Brugieres L, Geoerger B, Turner SD, Cuesta-Mateos C, D'Aliberti D, Mologni L, Piazza R, Gambacorti-Passerini C, Inghirami GG, Chiono V, Kamm RD, Hirsch E, Koch R, Weinstock DM, Aster JC, Voena C, Chiarle R
Sci Transl Med 2023 Jun 28;15(702):eabo3826. doi: 10.1126/scitranslmed.abo3826. PMID: 37379367Free PMC Article
Intratumoral CD8(+) T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer.
Virassamy B, Caramia F, Savas P, Sant S, Wang J, Christo SN, Byrne A, Clarke K, Brown E, Teo ZL, von Scheidt B, Freestone D, Gandolfo LC, Weber K, Teply-Szymanski J, Li R, Luen SJ, Denkert C, Loibl S, Lucas O, Swanton C, Speed TP, Darcy PK, Neeson PJ, Mackay LK, Loi S
Cancer Cell 2023 Mar 13;41(3):585-601.e8. Epub 2023 Feb 23 doi: 10.1016/j.ccell.2023.01.004. PMID: 36827978
HDL in the 21st Century: A Multifunctional Roadmap for Future HDL Research.
Rohatgi A, Westerterp M, von Eckardstein A, Remaley A, Rye KA
Circulation 2021 Jun 8;143(23):2293-2309. Epub 2021 Jun 7 doi: 10.1161/CIRCULATIONAHA.120.044221. PMID: 34097448Free PMC Article
The calcium-sensing receptor in physiology and in calcitropic and noncalcitropic diseases.
Hannan FM, Kallay E, Chang W, Brandi ML, Thakker RV
Nat Rev Endocrinol 2018 Dec;15(1):33-51. doi: 10.1038/s41574-018-0115-0. PMID: 30443043Free PMC Article

Clinical prediction guides

Assessing the causal relationship between 731 immunophenotypes and the risk of lung cancer: a bidirectional mendelian randomization study.
Xu M, Li C, Xiang L, Chen S, Chen L, Ling G, Hu Y, Yang L, Yuan X, Xia X, Zhang H
BMC Cancer 2024 Feb 26;24(1):270. doi: 10.1186/s12885-024-12014-1. PMID: 38408977Free PMC Article
G protein-coupled estrogen receptor activates PI3K/AKT/mTOR signaling to suppress ferroptosis via SREBP1/SCD1-mediated lipogenesis.
Chen J, Zhao R, Wang Y, Xiao H, Lin W, Diao M, He S, Mei P, Liao Y
Mol Med 2024 Feb 21;30(1):28. doi: 10.1186/s10020-023-00763-x. PMID: 38383297Free PMC Article
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma.
Mastini C, Campisi M, Patrucco E, Mura G, Ferreira A, Costa C, Ambrogio C, Germena G, Martinengo C, Peola S, Mota I, Vissio E, Molinaro L, Arigoni M, Olivero M, Calogero R, Prokoph N, Tabbò F, Shoji B, Brugieres L, Geoerger B, Turner SD, Cuesta-Mateos C, D'Aliberti D, Mologni L, Piazza R, Gambacorti-Passerini C, Inghirami GG, Chiono V, Kamm RD, Hirsch E, Koch R, Weinstock DM, Aster JC, Voena C, Chiarle R
Sci Transl Med 2023 Jun 28;15(702):eabo3826. doi: 10.1126/scitranslmed.abo3826. PMID: 37379367Free PMC Article
Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma.
Zhang X, Xu Y, Ma L, Yu K, Niu Y, Xu X, Shi Y, Guo S, Xue X, Wang Y, Qiu S, Cui J, Wang H, Tian X, Miao Y, Meng F, Qiao Y, Yu Y, Wang J
Cancer Commun (Lond) 2022 Apr;42(4):287-313. Epub 2022 Feb 20 doi: 10.1002/cac2.12275. PMID: 35184419Free PMC Article
Cancer immunotherapy.
Richman SP, Gutterman JU, Hersh EM
Can Med Assoc J 1979 Feb 3;120(3):322-4, 329. PMID: 371776Free PMC Article

Recent systematic reviews

Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies.
Garcia L, Pearce M, Abbas A, Mok A, Strain T, Ali S, Crippa A, Dempsey PC, Golubic R, Kelly P, Laird Y, McNamara E, Moore S, de Sa TH, Smith AD, Wijndaele K, Woodcock J, Brage S
Br J Sports Med 2023 Aug;57(15):979-989. Epub 2023 Feb 28 doi: 10.1136/bjsports-2022-105669. PMID: 36854652Free PMC Article
Evidence Update on the Relationship between Diet and the Most Common Cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: A Systematic Review.
Ubago-Guisado E, Rodríguez-Barranco M, Ching-López A, Petrova D, Molina-Montes E, Amiano P, Barricarte-Gurrea A, Chirlaque MD, Agudo A, Sánchez MJ
Nutrients 2021 Oct 13;13(10) doi: 10.3390/nu13103582. PMID: 34684583Free PMC Article
Citrus fruit intake and lung cancer risk: A meta-analysis of observational studies.
Wang J, Gao J, Xu HL, Qian Y, Xie L, Yu H, Qian BY
Pharmacol Res 2021 Apr;166:105430. Epub 2021 Jan 30 doi: 10.1016/j.phrs.2021.105430. PMID: 33529754
Selenium for preventing cancer.
Vinceti M, Filippini T, Del Giovane C, Dennert G, Zwahlen M, Brinkman M, Zeegers MP, Horneber M, D'Amico R, Crespi CM
Cochrane Database Syst Rev 2018 Jan 29;1(1):CD005195. doi: 10.1002/14651858.CD005195.pub4. PMID: 29376219Free PMC Article
Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.
Annane D, Pastores SM, Rochwerg B, Arlt W, Balk RA, Beishuizen A, Briegel J, Carcillo J, Christ-Crain M, Cooper MS, Marik PE, Umberto Meduri G, Olsen KM, Rodgers S, Russell JA, Van den Berghe G
Intensive Care Med 2017 Dec;43(12):1751-1763. Epub 2017 Sep 21 doi: 10.1007/s00134-017-4919-5. PMID: 28940011

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