U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Coronary artery disease, susceptibility to

MedGen UID:
333498
•Concept ID:
C1840169
•
Finding
Synonym: CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO
 
OMIM®: 147545; 168820

Professional guidelines

PubMed

Glutathione S-transferase M1 and T1 (rs4025935 and rs71748309) null genotypes are associated with increased susceptibility to coronary artery disease in Indian populations.
Mir R, Bhat MA, Javaid J, Shah N, Kumar P, Sharma E, Jhu C, Basak S, Amle D, Ray PC, Saxena A, Banu S
Acta Cardiol 2016;71(6):678-684. doi: 10.2143/AC.71.6.3178186. PMID: 27920455
Translating genomic analyses into improved management of coronary artery disease.
Johansen CT, Lanktree MB, Hegele RA
Future Cardiol 2010 Jul;6(4):507-21. doi: 10.2217/fca.10.28. PMID: 20608823
Ethical issues in molecular screening for heterozygous familial hypercholesterolemia: the complexity of dealing with genetic susceptibility to coronary artery disease.
Gaudet D, Gagné C, Perron P, Couture P, Tonstad S
Community Genet 1999;2(1):2-8. doi: 10.1159/000016176. PMID: 11658106

Recent clinical studies

Etiology

Causal Association Between Anemia and Cardiovascular Disease: A 2-Sample Bidirectional Mendelian Randomization Study.
Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z
J Am Heart Assoc 2023 Jun 20;12(12):e029689. Epub 2023 Jun 10 doi: 10.1161/JAHA.123.029689. PMID: 37301769Free PMC Article
Endothelial Dysfunction, Inflammation and Coronary Artery Disease: Potential Biomarkers and Promising Therapeutical Approaches.
Medina-Leyte DJ, Zepeda-García O, Domínguez-Pérez M, González-Garrido A, Villarreal-Molina T, Jacobo-Albavera L
Int J Mol Sci 2021 Apr 8;22(8) doi: 10.3390/ijms22083850. PMID: 33917744Free PMC Article
Screening and Risk Assessment of Coronary Artery Disease in Patients With Type 2 Diabetes: An Updated Review.
Patsouras A, Farmaki P, Garmpi A, Damaskos C, Garmpis N, Mantas D, Diamantis E
In Vivo 2019 Jul-Aug;33(4):1039-1049. doi: 10.21873/invivo.11572. PMID: 31280191Free PMC Article
A review on coronary artery disease, its risk factors, and therapeutics.
Malakar AK, Choudhury D, Halder B, Paul P, Uddin A, Chakraborty S
J Cell Physiol 2019 Aug;234(10):16812-16823. Epub 2019 Feb 20 doi: 10.1002/jcp.28350. PMID: 30790284
Genetics of coronary artery disease.
Lieb W, Vasan RS
Circulation 2013 Sep 3;128(10):1131-8. doi: 10.1161/CIRCULATIONAHA.113.005350. PMID: 24002717Free PMC Article

Diagnosis

Causal Association Between Anemia and Cardiovascular Disease: A 2-Sample Bidirectional Mendelian Randomization Study.
Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z
J Am Heart Assoc 2023 Jun 20;12(12):e029689. Epub 2023 Jun 10 doi: 10.1161/JAHA.123.029689. PMID: 37301769Free PMC Article
Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction.
Nurmohamed NS, Kraaijenhof JM, Mayr M, Nicholls SJ, Koenig W, Catapano AL, Stroes ESG
Eur Heart J 2023 May 7;44(18):1594-1607. doi: 10.1093/eurheartj/ehad161. PMID: 36988179Free PMC Article
Screening and Risk Assessment of Coronary Artery Disease in Patients With Type 2 Diabetes: An Updated Review.
Patsouras A, Farmaki P, Garmpi A, Damaskos C, Garmpis N, Mantas D, Diamantis E
In Vivo 2019 Jul-Aug;33(4):1039-1049. doi: 10.21873/invivo.11572. PMID: 31280191Free PMC Article
A review on coronary artery disease, its risk factors, and therapeutics.
Malakar AK, Choudhury D, Halder B, Paul P, Uddin A, Chakraborty S
J Cell Physiol 2019 Aug;234(10):16812-16823. Epub 2019 Feb 20 doi: 10.1002/jcp.28350. PMID: 30790284
Genetics of coronary artery disease.
Lieb W, Vasan RS
Circulation 2013 Sep 3;128(10):1131-8. doi: 10.1161/CIRCULATIONAHA.113.005350. PMID: 24002717Free PMC Article

Therapy

Causal Association Between Anemia and Cardiovascular Disease: A 2-Sample Bidirectional Mendelian Randomization Study.
Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z
J Am Heart Assoc 2023 Jun 20;12(12):e029689. Epub 2023 Jun 10 doi: 10.1161/JAHA.123.029689. PMID: 37301769Free PMC Article
Relationship between NAFLD and coronary artery disease: A Mendelian randomization study.
Ren Z, Simons PIHG, Wesselius A, Stehouwer CDA, Brouwers MCGJ
Hepatology 2023 Jan 1;77(1):230-238. Epub 2022 May 18 doi: 10.1002/hep.32534. PMID: 35441719Free PMC Article
Evaluation and Treatment of Amiodarone-Induced Thyroid Disorders.
Ylli D, Wartofsky L, Burman KD
J Clin Endocrinol Metab 2021 Jan 1;106(1):226-236. doi: 10.1210/clinem/dgaa686. PMID: 33159436
Coronary Artery Disease.
Agrawal H, Choy HK, Liu J, Auyoung M, Albert MA
Arterioscler Thromb Vasc Biol 2020 Jul;40(7):e185-e192. Epub 2020 Jun 24 doi: 10.1161/ATVBAHA.120.313608. PMID: 32579480
Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis.
Ference BA, Yoo W, Alesh I, Mahajan N, Mirowska KK, Mewada A, Kahn J, Afonso L, Williams KA Sr, Flack JM
J Am Coll Cardiol 2012 Dec 25;60(25):2631-9. Epub 2012 Oct 17 doi: 10.1016/j.jacc.2012.09.017. PMID: 23083789

Prognosis

Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction.
Nurmohamed NS, Kraaijenhof JM, Mayr M, Nicholls SJ, Koenig W, Catapano AL, Stroes ESG
Eur Heart J 2023 May 7;44(18):1594-1607. doi: 10.1093/eurheartj/ehad161. PMID: 36988179Free PMC Article
Polygenic risk scores for the prediction of cardiometabolic disease.
O'Sullivan JW, Ashley EA, Elliott PM
Eur Heart J 2023 Jan 7;44(2):89-99. doi: 10.1093/eurheartj/ehac648. PMID: 36478054
Relationship between NAFLD and coronary artery disease: A Mendelian randomization study.
Ren Z, Simons PIHG, Wesselius A, Stehouwer CDA, Brouwers MCGJ
Hepatology 2023 Jan 1;77(1):230-238. Epub 2022 May 18 doi: 10.1002/hep.32534. PMID: 35441719Free PMC Article
Screening and Risk Assessment of Coronary Artery Disease in Patients With Type 2 Diabetes: An Updated Review.
Patsouras A, Farmaki P, Garmpi A, Damaskos C, Garmpis N, Mantas D, Diamantis E
In Vivo 2019 Jul-Aug;33(4):1039-1049. doi: 10.21873/invivo.11572. PMID: 31280191Free PMC Article
Associations of Combined Genetic and Lifestyle Risks With Incident Cardiovascular Disease and Diabetes in the UK Biobank Study.
Said MA, Verweij N, van der Harst P
JAMA Cardiol 2018 Aug 1;3(8):693-702. doi: 10.1001/jamacardio.2018.1717. PMID: 29955826Free PMC Article

Clinical prediction guides

Causal Association Between Anemia and Cardiovascular Disease: A 2-Sample Bidirectional Mendelian Randomization Study.
Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z
J Am Heart Assoc 2023 Jun 20;12(12):e029689. Epub 2023 Jun 10 doi: 10.1161/JAHA.123.029689. PMID: 37301769Free PMC Article
Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction.
Nurmohamed NS, Kraaijenhof JM, Mayr M, Nicholls SJ, Koenig W, Catapano AL, Stroes ESG
Eur Heart J 2023 May 7;44(18):1594-1607. doi: 10.1093/eurheartj/ehad161. PMID: 36988179Free PMC Article
Polygenic risk scores for the prediction of cardiometabolic disease.
O'Sullivan JW, Ashley EA, Elliott PM
Eur Heart J 2023 Jan 7;44(2):89-99. doi: 10.1093/eurheartj/ehac648. PMID: 36478054
Screening and Risk Assessment of Coronary Artery Disease in Patients With Type 2 Diabetes: An Updated Review.
Patsouras A, Farmaki P, Garmpi A, Damaskos C, Garmpis N, Mantas D, Diamantis E
In Vivo 2019 Jul-Aug;33(4):1039-1049. doi: 10.21873/invivo.11572. PMID: 31280191Free PMC Article
Genetics of coronary artery disease.
Lieb W, Vasan RS
Circulation 2013 Sep 3;128(10):1131-8. doi: 10.1161/CIRCULATIONAHA.113.005350. PMID: 24002717Free PMC Article

Recent systematic reviews

Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.
Gill D, Cameron AC, Burgess S, Li X, Doherty DJ, Karhunen V, Abdul-Rahim AH, Taylor-Rowan M, Zuber V, Tsao PS, Klarin D; VA Million Veteran Program, Evangelou E, Elliott P, Damrauer SM, Quinn TJ, Dehghan A, Theodoratou E, Dawson J, Tzoulaki I
Hypertension 2021 Feb;77(2):383-392. Epub 2020 Dec 28 doi: 10.1161/HYPERTENSIONAHA.120.16547. PMID: 33356394Free PMC Article
Association of polymorphisms in ADAMTS-7 gene with the susceptibility to coronary artery disease - a systematic review and meta-analysis.
Hosseini DK, Ataikia S, Hosseini HK, Han B, Sun H
Aging (Albany NY) 2020 Oct 29;12(20):20915-20923. doi: 10.18632/aging.104118. PMID: 33122452Free PMC Article
Osteoprotegerin SNP associations with coronary artery disease and ischemic stroke risk: a meta-analysis.
Wu J, Li X, Gao F, Gao S, Lyu J, Qiang H
Biosci Rep 2020 Oct 30;40(10) doi: 10.1042/BSR20202156. PMID: 32955093Free PMC Article
Human cytomegalovirus infection and coronary heart disease: a systematic review.
Du Y, Zhang G, Liu Z
Virol J 2018 Feb 6;15(1):31. doi: 10.1186/s12985-018-0937-3. PMID: 29409508Free PMC Article
Common Variants of Vitamin D Receptor Gene Polymorphisms and Susceptibility to Coronary Artery Disease: A Systematic Review and Meta-Analysis.
Alizadeh S, Djafarian K, Alizadeh H, Mohseni R, Shab-Bidar S
J Nutrigenet Nutrigenomics 2017;10(1-2):9-18. Epub 2017 Mar 29 doi: 10.1159/000455914. PMID: 28351026

Supplemental Content

Table of contents

    Genetic Testing Registry

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...