U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cataract 35(CTRCT35)

MedGen UID:
373050
Concept ID:
C1836272
Disease or Syndrome
Synonym: CTRCT35
 
Monarch Initiative: MONDO:0012260
OMIM®: 609376

Definition

A cataract that has material basis in variation in the region 19q13. [from MONDO]

Clinical features

From HPO
Cataract
MedGen UID:
39462
Concept ID:
C0086543
Disease or Syndrome
A cataract is an opacity or clouding that develops in the crystalline lens of the eye or in its capsule.

Professional guidelines

PubMed

Jones NP
Ocul Immunol Inflamm 2015 Apr;23(2):127-34. Epub 2014 Nov 13 doi: 10.3109/09273948.2014.968671. PMID: 25393634
Reynolds MG, Haimovici R, Flynn HW Jr, DiBernardo C, Byrne SF, Feuer W
Ophthalmology 1993 Apr;100(4):460-5. PMID: 8479701

Recent clinical studies

Etiology

Hjortdal J
Indian J Ophthalmol 2024 Jan 1;72(1):3-5. Epub 2023 Dec 22 doi: 10.4103/IJO.IJO_2767_23. PMID: 38131561Free PMC Article
Röggla V, Langenbucher A, Leydolt C, Schartmüller D, Schwarzenbacher L, Hoffmann P, Menapace R
Clin Exp Ophthalmol 2023 Aug;51(6):559-565. Epub 2023 Jun 1 doi: 10.1111/ceo.14261. PMID: 37264533
Mrugacz M, Pony-Uram M, Bryl A, Zorena K
Int J Mol Sci 2023 Mar 28;24(7) doi: 10.3390/ijms24076317. PMID: 37047290Free PMC Article
Bardoloi N, Sarkar S, Burgute PS, Ghosh D, Deb AK
Indian J Ophthalmol 2021 Jul;69(7):1781-1785. doi: 10.4103/ijo.IJO_2723_20. PMID: 34146028Free PMC Article
Huang Q, Huang Y, Luo Q, Fan W
BMC Ophthalmol 2018 Apr 17;18(1):99. doi: 10.1186/s12886-018-0770-x. PMID: 29665792Free PMC Article

Diagnosis

Ferguson EL, Thoma M, Buto PT, Wang J, Glymour MM, Hoffmann TJ, Choquet H, Andrews SJ, Yaffe K, Casaletto K, Brenowitz WD
JAMA Netw Open 2024 Jul 1;7(7):e2424539. doi: 10.1001/jamanetworkopen.2024.24539. PMID: 39078629Free PMC Article
Hjortdal J
Indian J Ophthalmol 2024 Jan 1;72(1):3-5. Epub 2023 Dec 22 doi: 10.4103/IJO.IJO_2767_23. PMID: 38131561Free PMC Article
Montesano G, Ometto G, Ahmed IIK, Ramulu PY, Chang DF, Crabb DP, Gazzard G
Am J Ophthalmol 2023 Jul;251:143-155. Epub 2023 Feb 21 doi: 10.1016/j.ajo.2023.02.008. PMID: 36813144
Zur D, Loewenstein A
Dev Ophthalmol 2017;58:178-190. Epub 2017 Mar 28 doi: 10.1159/000455280. PMID: 28351047
Navon SE
Int Ophthalmol Clin 1995 Winter;35(1):71-91. doi: 10.1097/00004397-199503510-00009. PMID: 7751137

Therapy

Ferguson EL, Thoma M, Buto PT, Wang J, Glymour MM, Hoffmann TJ, Choquet H, Andrews SJ, Yaffe K, Casaletto K, Brenowitz WD
JAMA Netw Open 2024 Jul 1;7(7):e2424539. doi: 10.1001/jamanetworkopen.2024.24539. PMID: 39078629Free PMC Article
Montesano G, Ometto G, Ahmed IIK, Ramulu PY, Chang DF, Crabb DP, Gazzard G
Am J Ophthalmol 2023 Jul;251:143-155. Epub 2023 Feb 21 doi: 10.1016/j.ajo.2023.02.008. PMID: 36813144
Liu SH, Saldanha IJ, Abraham AG, Rittiphairoj T, Hauswirth S, Gregory D, Ifantides C, Li T
Cochrane Database Syst Rev 2022 Oct 21;10(10):CD015070. doi: 10.1002/14651858.CD015070.pub2. PMID: 36269562Free PMC Article
Smith AF, Klotz A, Wormstone IM
Drug Discov Today 2016 Mar;21(3):510-6. Epub 2016 Jan 8 doi: 10.1016/j.drudis.2016.01.001. PMID: 26775751
Angra SK, Goyal JL
Indian J Ophthalmol 1987 Mar-Apr;35(2):82-3. PMID: 3450624

Prognosis

Strelnikov JI, Rao R, Majidi S, Lueder G, Lee A, Reynolds MM
Eye (Lond) 2024 Jun;38(8):1462-1470. Epub 2024 Jan 11 doi: 10.1038/s41433-023-02921-1. PMID: 38212403Free PMC Article
Röggla V, Langenbucher A, Leydolt C, Schartmüller D, Schwarzenbacher L, Hoffmann P, Menapace R
Clin Exp Ophthalmol 2023 Aug;51(6):559-565. Epub 2023 Jun 1 doi: 10.1111/ceo.14261. PMID: 37264533
Bothun ED, Shainberg MJ, Christiansen SP, Vanderveen DK, Neely DE, Kruger SJ, Cotsonis G, Lambert SR; Infant Aphakic Treatment Study
J AAPOS 2022 Aug;26(4):174.e1-174.e4. Epub 2022 Jul 14 doi: 10.1016/j.jaapos.2022.05.003. PMID: 35843488Free PMC Article
Smith AF, Klotz A, Wormstone IM
Drug Discov Today 2016 Mar;21(3):510-6. Epub 2016 Jan 8 doi: 10.1016/j.drudis.2016.01.001. PMID: 26775751
Nuzzi R, Schiavino R
Panminerva Med 1993 Mar;35(1):36-46. PMID: 8316402

Clinical prediction guides

Röggla V, Langenbucher A, Leydolt C, Schartmüller D, Schwarzenbacher L, Hoffmann P, Menapace R
Clin Exp Ophthalmol 2023 Aug;51(6):559-565. Epub 2023 Jun 1 doi: 10.1111/ceo.14261. PMID: 37264533
Khavandi S, Lim E, Higham A, de Pennington N, Bindra M, Maling S, Adams M, Mole G
Eye (Lond) 2023 Jul;37(10):2069-2076. Epub 2022 Oct 23 doi: 10.1038/s41433-022-02289-8. PMID: 36274084Free PMC Article
Liu SH, Saldanha IJ, Abraham AG, Rittiphairoj T, Hauswirth S, Gregory D, Ifantides C, Li T
Cochrane Database Syst Rev 2022 Oct 21;10(10):CD015070. doi: 10.1002/14651858.CD015070.pub2. PMID: 36269562Free PMC Article
Kato A, Horita N, Namkoong H, Nomura E, Masuhara N, Kaneko T, Mizuki N, Takeuchi M
Sci Rep 2022 Oct 18;12(1):17416. doi: 10.1038/s41598-022-21423-w. PMID: 36258003Free PMC Article
Clements RS Jr
Drugs 1986;32 Suppl 2:3-5. doi: 10.2165/00003495-198600322-00003. PMID: 3792230

Recent systematic reviews

Koosha N, Riazi MS, Janfaza P, Mohammadbeigy I, Rahimi A, Khoshali M, Pourazizi M, Peyman A
J Cataract Refract Surg 2024 Jul 1;50(7):767-776. doi: 10.1097/j.jcrs.0000000000001426. PMID: 38353281
Luo N, Liu M, Hao M, Xu R, Wang F, Zhang W
BMJ Open 2023 Apr 20;13(4):e065921. doi: 10.1136/bmjopen-2022-065921. PMID: 37080625Free PMC Article
de Muijnck C, Brink JBT, Bergen AA, Boon CJF, van Genderen MM
Surv Ophthalmol 2023 Jul-Aug;68(4):641-654. Epub 2023 Feb 9 doi: 10.1016/j.survophthal.2023.01.012. PMID: 36764396
Liu SH, Saldanha IJ, Abraham AG, Rittiphairoj T, Hauswirth S, Gregory D, Ifantides C, Li T
Cochrane Database Syst Rev 2022 Oct 21;10(10):CD015070. doi: 10.1002/14651858.CD015070.pub2. PMID: 36269562Free PMC Article
Kato A, Horita N, Namkoong H, Nomura E, Masuhara N, Kaneko T, Mizuki N, Takeuchi M
Sci Rep 2022 Oct 18;12(1):17416. doi: 10.1038/s41598-022-21423-w. PMID: 36258003Free PMC Article

Supplemental Content

Table of contents

    Genetic Testing Registry

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...