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Conjugate gaze palsy

MedGen UID:
675273
•Concept ID:
C0702143
•
Disease or Syndrome
Synonyms: Gaze palsy; Supranuclear ocular palsy
SNOMED CT: Palsy of conjugate gaze (1534008); Conjugate gaze palsy (1534008)
 
Monarch Initiative: MONDO:0001527

Recent clinical studies

Etiology

A Rare Multinuclear Lesion Secondary to Multifactorial Ischemic Stroke: A Case Report on Eight-and-a-Half Syndrome.
Vander Zee B, Zineldine O, Diep-Plagie L
S D Med 2024 Jun;77(6):248-250. PMID: 39013095
Pontine warning syndrome.
Saposnik G, Noel de Tilly L, Caplan LR
Arch Neurol 2008 Oct;65(10):1375-7. doi: 10.1001/archneur.65.10.1375. PMID: 18852355
The clinical syndrome and etiological mechanism of infarction involving the nucleus prepositus hypoglossi.
Cho HJ, Choi HY, Kim YD, Seo SW, Heo JH
Cerebrovasc Dis 2008;26(2):178-83. Epub 2008 Jul 15 doi: 10.1159/000145325. PMID: 18628616
Nuclear and infranuclear disorders.
Meienberg O, Müri R
Baillieres Clin Neurol 1992 Aug;1(2):417-34. PMID: 1344077
Abnormalities of horizontal gaze. Clinical, oculographic and magnetic resonance imaging findings. I. Abducens palsy.
Bronstein AM, Morris J, Du Boulay G, Gresty MA, Rudge P
J Neurol Neurosurg Psychiatry 1990 Mar;53(3):194-9. doi: 10.1136/jnnp.53.3.194. PMID: 2324751Free PMC Article

Diagnosis

A Rare Case Report of Eight Syndrome Secondary to Syringomyelia Associated with Type I Chiari Malformation.
Top Kartı D, Kıyat P, Kartı Ö, Çelebisoy N
Turk J Ophthalmol 2023 Jun 21;53(3):197-199. doi: 10.4274/tjo.galenos.2023.19054. PMID: 37345329Free PMC Article
Pontine warning syndrome.
Saposnik G, Noel de Tilly L, Caplan LR
Arch Neurol 2008 Oct;65(10):1375-7. doi: 10.1001/archneur.65.10.1375. PMID: 18852355
Is this patient having a stroke?
Goldstein LB, Simel DL
JAMA 2005 May 18;293(19):2391-402. doi: 10.1001/jama.293.19.2391. PMID: 15900010
Neuro-ophthalmic findings in acquired immunodeficiency syndrome.
Mansour AM
J Clin Neuroophthalmol 1990 Sep;10(3):167-74. PMID: 2168900
Lateral tegmental brainstem hemorrhages.
Caplan LR, Goodwin JA
Neurology 1982 Mar;32(3):252-60. doi: 10.1212/wnl.32.3.252. PMID: 7199635

Therapy

Acute myeloid leukemia presenting as one-and-a-half syndrome.
Hsu WH, Chu SJ, Tsai WC, Tsao YT
Am J Emerg Med 2008 May;26(4):513.e1-2. doi: 10.1016/j.ajem.2007.05.014. PMID: 18410825
Isolated brain stem tuberculoma presenting with one and a half syndrome.
Enani M, Al-Nakhli DJ, Bakhsh E
Saudi Med J 2006 Sep;27(9):1407-11. PMID: 16951784
Case report: one-and-a-half-syndrome and tuberculosis of the pons in a patient with AIDS.
Minagar A, Schatz NJ, Glaser JS
AIDS Patient Care STDS 2000 Sep;14(9):461-4. doi: 10.1089/108729100438836. PMID: 11051628

Prognosis

Pontine warning syndrome.
Saposnik G, Noel de Tilly L, Caplan LR
Arch Neurol 2008 Oct;65(10):1375-7. doi: 10.1001/archneur.65.10.1375. PMID: 18852355
Is this patient having a stroke?
Goldstein LB, Simel DL
JAMA 2005 May 18;293(19):2391-402. doi: 10.1001/jama.293.19.2391. PMID: 15900010
Abnormalities of horizontal gaze. Clinical, oculographic and magnetic resonance imaging findings. I. Abducens palsy.
Bronstein AM, Morris J, Du Boulay G, Gresty MA, Rudge P
J Neurol Neurosurg Psychiatry 1990 Mar;53(3):194-9. doi: 10.1136/jnnp.53.3.194. PMID: 2324751Free PMC Article

Clinical prediction guides

Surgical planning and innervation in pontine gaze palsy with ipsilateral esotropia.
Somer D, Cinar FG, Kaderli A, Ornek F
J AAPOS 2016 Oct;20(5):410-414.e3. Epub 2016 Sep 17 doi: 10.1016/j.jaapos.2016.07.222. PMID: 27651233
Pontine warning syndrome.
Saposnik G, Noel de Tilly L, Caplan LR
Arch Neurol 2008 Oct;65(10):1375-7. doi: 10.1001/archneur.65.10.1375. PMID: 18852355
Is this patient having a stroke?
Goldstein LB, Simel DL
JAMA 2005 May 18;293(19):2391-402. doi: 10.1001/jama.293.19.2391. PMID: 15900010
Nuclear and infranuclear disorders.
Meienberg O, Müri R
Baillieres Clin Neurol 1992 Aug;1(2):417-34. PMID: 1344077
Abnormalities of horizontal gaze. Clinical, oculographic and magnetic resonance imaging findings. I. Abducens palsy.
Bronstein AM, Morris J, Du Boulay G, Gresty MA, Rudge P
J Neurol Neurosurg Psychiatry 1990 Mar;53(3):194-9. doi: 10.1136/jnnp.53.3.194. PMID: 2324751Free PMC Article

Recent systematic reviews

Is this patient having a stroke?
Goldstein LB, Simel DL
JAMA 2005 May 18;293(19):2391-402. doi: 10.1001/jama.293.19.2391. PMID: 15900010

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