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Female Malignant Nipple Neoplasm

MedGen UID:
882994
•Concept ID:
C0948966
•
Neoplastic Process

Definition

A malignant neoplasm that affects the area of the nipple in females. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFemale Malignant Nipple Neoplasm

Professional guidelines

PubMed

Robotic Versus Conventional or Endoscopic-assisted Nipple-sparing Mastectomy and Immediate Prosthesis Breast Reconstruction in the Management of Breast Cancer: A Prospectively Designed Multicenter Trial Comparing Clinical Outcomes, Medical Cost, and Patient-reported Outcomes (RCENSM-P).
Lai HW, Chen DR, Liu LC, Chen ST, Kuo YL, Lin SL, Wu YC, Huang TC, Hung CS, Lin YJ, Tseng HS, Mok CW, Cheng FT
Ann Surg 2024 Jan 1;279(1):138-146. Epub 2023 May 25 doi: 10.1097/SLA.0000000000005924. PMID: 37226826Free PMC Article
Paget's disease of the breast: diagnosis and management.
Hudson-Phillips S, Cox K, Patel P, Al Sarakbi W
Br J Hosp Med (Lond) 2023 Jan 2;84(1):1-8. Epub 2023 Jan 24 doi: 10.12968/hmed.2022.0439. PMID: 36708338
Management of Nipple Discharge.
Vavolizza RD, Dengel LT
Surg Clin North Am 2022 Dec;102(6):1077-1087. doi: 10.1016/j.suc.2022.06.006. PMID: 36335926

Recent clinical studies

Etiology

Benign Breast Disease.
Pleasant V
Clin Obstet Gynecol 2022 Sep 1;65(3):448-460. Epub 2022 Jun 16 doi: 10.1097/GRF.0000000000000719. PMID: 35708970
A Randomized Trial of Robotic Mastectomy Versus Open Surgery in Women With Breast Cancer or BrCA Mutation.
Toesca A, Sangalli C, Maisonneuve P, Massari G, Girardi A, Baker JL, Lissidini G, Invento A, Farante G, Corso G, Rietjens M, Peradze N, Gottardi A, Magnoni F, Bottiglieri L, Lazzeroni M, Montagna E, Labo P, Orecchia R, Galimberti V, Intra M, Sacchini V, Veronesi P
Ann Surg 2022 Jul 1;276(1):11-19. Epub 2021 Jun 9 doi: 10.1097/SLA.0000000000004969. PMID: 34597010
Tumor-to-Nipple Distance and the Safety of Nipple-Sparing Mastectomy.
Wu ZY, Han HH, Eom JS, Ahn SH, Ko B
Plast Reconstr Surg 2021 Jul 1;148(1):158e-159e. doi: 10.1097/PRS.0000000000008011. PMID: 34110325
The evolution of autologous breast reconstruction.
Costanzo D, Klinger M, Lisa A, Maione L, Battistini A, Vinci V
Breast J 2020 Nov;26(11):2223-2225. Epub 2020 Sep 10 doi: 10.1111/tbj.14025. PMID: 32909653
The modern approach to the nipple-sparing mastectomy.
Kopkash K, Sisco M, Poli E, Seth A, Pesce C
J Surg Oncol 2020 Jul;122(1):29-35. Epub 2020 Mar 26 doi: 10.1002/jso.25909. PMID: 32219847

Diagnosis

Paget's disease of the breast: diagnosis and management.
Hudson-Phillips S, Cox K, Patel P, Al Sarakbi W
Br J Hosp Med (Lond) 2023 Jan 2;84(1):1-8. Epub 2023 Jan 24 doi: 10.12968/hmed.2022.0439. PMID: 36708338
Dermatological Conditions of the Breast.
Pulusani S, Jones E, Throckmorton AD
Surg Clin North Am 2022 Dec;102(6):1043-1063. doi: 10.1016/j.suc.2022.07.003. PMID: 36335924
Benign Breast Disease.
Pleasant V
Clin Obstet Gynecol 2022 Sep 1;65(3):448-460. Epub 2022 Jun 16 doi: 10.1097/GRF.0000000000000719. PMID: 35708970
Nipple discharge.
Labib PL, Gallegos N, Hegarty D
BMJ 2015 Jul 21;351:h3123. doi: 10.1136/bmj.h3123. PMID: 26198815
Nipple discharge screening.
Zervoudis S, Iatrakis G, Economides P, Polyzos D, Navrozoglou I
Womens Health (Lond) 2010 Jan;6(1):135-51. doi: 10.2217/whe.09.81. PMID: 20050819

Therapy

The evolution of autologous breast reconstruction.
Costanzo D, Klinger M, Lisa A, Maione L, Battistini A, Vinci V
Breast J 2020 Nov;26(11):2223-2225. Epub 2020 Sep 10 doi: 10.1111/tbj.14025. PMID: 32909653
Nipple-Areola Complex Reconstruction.
Sisti A
Medicina (Kaunas) 2020 Jun 16;56(6) doi: 10.3390/medicina56060296. PMID: 32560062Free PMC Article
Nipple-sparing and skin-sparing mastectomy: Review of aims, oncological safety and contraindications.
Galimberti V, Vicini E, Corso G, Morigi C, Fontana S, Sacchini V, Veronesi P
Breast 2017 Aug;34 Suppl 1(Suppl 1):S82-S84. Epub 2017 Jun 30 doi: 10.1016/j.breast.2017.06.034. PMID: 28673535Free PMC Article
Conservative mastectomies.
Nava MB, Catanuto G, Pennati A, Garganese G, Spano A
Aesthetic Plast Surg 2009 Sep;33(5):681-6. Epub 2009 Jul 9 doi: 10.1007/s00266-009-9382-4. PMID: 19588190
Breast reconstruction.
Antoniuk PM
Obstet Gynecol Clin North Am 2002 Mar;29(1):209-23, ix. doi: 10.1016/s0889-8545(03)00063-9. PMID: 11892868

Prognosis

A multidisciplinary view of mastectomy and breast reconstruction: Understanding the challenges.
Kaidar-Person O, Offersen BV, Boersma LJ, de Ruysscher D, Tramm T, Kühn T, Gentilini O, Mátrai Z, Poortmans P
Breast 2021 Apr;56:42-52. Epub 2021 Feb 10 doi: 10.1016/j.breast.2021.02.004. PMID: 33610903Free PMC Article
Nipple Sparing Mastectomy as a Risk-Reducing Procedure for BRCA-Mutated Patients.
Rocco N, Montagna G, Criscitiello C, Nava MB, Privitera F, Taher W, Gloria A, Catanuto G
Genes (Basel) 2021 Feb 10;12(2) doi: 10.3390/genes12020253. PMID: 33578759Free PMC Article
Advanced locoregional therapies in breast.
Mitchell S, Klimberg VS, Ochoa D, Rusby J, Chang D, Patel R, Park J, Korn JM, Djohan R
Ann Surg Oncol 2014 Oct;21(10):3198-203. Epub 2014 Jul 30 doi: 10.1245/s10434-014-3916-y. PMID: 25074662
Paget's disease of the nipple.
Sandoval-Leon AC, Drews-Elger K, Gomez-Fernandez CR, Yepes MM, Lippman ME
Breast Cancer Res Treat 2013 Aug;141(1):1-12. Epub 2013 Aug 9 doi: 10.1007/s10549-013-2661-4. PMID: 23929251
Ductoscopy-assisted microdochectomy.
Escobar PF, Baynes D, Crowe JP
Int J Fertil Womens Med 2004 Sep-Oct;49(5):222-4. PMID: 15633479

Clinical prediction guides

Robotic Versus Conventional or Endoscopic-assisted Nipple-sparing Mastectomy and Immediate Prosthesis Breast Reconstruction in the Management of Breast Cancer: A Prospectively Designed Multicenter Trial Comparing Clinical Outcomes, Medical Cost, and Patient-reported Outcomes (RCENSM-P).
Lai HW, Chen DR, Liu LC, Chen ST, Kuo YL, Lin SL, Wu YC, Huang TC, Hung CS, Lin YJ, Tseng HS, Mok CW, Cheng FT
Ann Surg 2024 Jan 1;279(1):138-146. Epub 2023 May 25 doi: 10.1097/SLA.0000000000005924. PMID: 37226826Free PMC Article
A Randomized Trial of Robotic Mastectomy Versus Open Surgery in Women With Breast Cancer or BrCA Mutation.
Toesca A, Sangalli C, Maisonneuve P, Massari G, Girardi A, Baker JL, Lissidini G, Invento A, Farante G, Corso G, Rietjens M, Peradze N, Gottardi A, Magnoni F, Bottiglieri L, Lazzeroni M, Montagna E, Labo P, Orecchia R, Galimberti V, Intra M, Sacchini V, Veronesi P
Ann Surg 2022 Jul 1;276(1):11-19. Epub 2021 Jun 9 doi: 10.1097/SLA.0000000000004969. PMID: 34597010
ASO Author Reflections: Diagnostic Accuracy of Nipple Aspirate Fluid Cytology in Asymptomatic Patients and Its Predictive Validity on Future Risk of Breast Cancer: A Meta-Analysis and Systematic Review of the Literature.
Jiwa N, Takats Z, Leff DR
Ann Surg Oncol 2021 Jul;28(7):3761-3762. Epub 2020 Nov 18 doi: 10.1245/s10434-020-09355-z. PMID: 33206265Free PMC Article
Nipple-sparing mastectomy--is it worth the risk?
Petit JY, Veronesi U, Lohsiriwat V, Rey P, Curigliano G, Martella S, Garusi C, De Lorenzi F, Manconi A, Botteri E, Didier F, Orecchia R, Rietjens M
Nat Rev Clin Oncol 2011 Oct 25;8(12):742-7. doi: 10.1038/nrclinonc.2011.159. PMID: 22024947
Ductoscopy-assisted microdochectomy.
Escobar PF, Baynes D, Crowe JP
Int J Fertil Womens Med 2004 Sep-Oct;49(5):222-4. PMID: 15633479

Recent systematic reviews

Postmastectomy Reconstruction in Male Breast Cancer.
Deldar R, Sayyed AA, Towfighi P, Aminpour N, Sogunro O, Son JD, Fan KL, Song DH
Breast J 2022;2022:5482261. Epub 2022 Mar 29 doi: 10.1155/2022/5482261. PMID: 35711890Free PMC Article
ASO Authors Reflection: Diagnostic Accuracy of Nipple Discharge Fluid Cytology: A Meta-Analysis and Systematic Review of the Literature.
Jiwa N, Leff D
Ann Surg Oncol 2022 Mar;29(3):1787-1788. Epub 2021 Nov 20 doi: 10.1245/s10434-021-11094-8. PMID: 34802102Free PMC Article
ASO Author Reflections: Diagnostic Accuracy of Nipple Aspirate Fluid Cytology in Asymptomatic Patients and Its Predictive Validity on Future Risk of Breast Cancer: A Meta-Analysis and Systematic Review of the Literature.
Jiwa N, Takats Z, Leff DR
Ann Surg Oncol 2021 Jul;28(7):3761-3762. Epub 2020 Nov 18 doi: 10.1245/s10434-020-09355-z. PMID: 33206265Free PMC Article
Diagnostic Accuracy of Nipple Aspirate Fluid Cytology in Asymptomatic Patients: A Meta-analysis and Systematic Review of the Literature.
Jiwa N, Gandhewar R, Chauhan H, Ashrafian H, Kumar S, Wright C, Takats Z, Leff DR
Ann Surg Oncol 2021 Jul;28(7):3751-3760. Epub 2020 Nov 9 doi: 10.1245/s10434-020-09313-9. PMID: 33165721Free PMC Article
Comparison of one-stage vs two-stage prosthesis-based breast reconstruction: a systematic review and meta-analysis.
Lee KT, Mun GH
Am J Surg 2016 Aug;212(2):336-44. Epub 2015 Sep 30 doi: 10.1016/j.amjsurg.2015.07.015. PMID: 26499053

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