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Onychogryphosis

MedGen UID:
82671
•Concept ID:
C0263537
•
Disease or Syndrome
Synonym: Thick nail
SNOMED CT: OG - Onychogryphosis (52897009); Onychogryposis (52897009); Hook nail (52897009); Onychogryphosis (52897009)
 
HPO: HP:0001805

Definition

Onychogryphosis is a disorder of nail plate growth that is clinically characterized by an opaque, yellow-brown thickening of the nail plate with associated gross hyperkeratosis, elongation, and increased curvature. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOnychogryphosis

Professional guidelines

PubMed

A new hope in the treatment of onychogryphosis due to acquired malalignment of great toenails: intramatrix dexpanthenol injection.
Kutlu Ö, Wollina U, Göktay F
J Dermatolog Treat 2023 Dec;34(1):2187658. doi: 10.1080/09546634.2023.2187658. PMID: 36877818
Total Matricectomy and V-Y Advancement Flap Technique in the Treatment of Onychogryphosis.
Gürbüz K, Ozan F, Kayali C, Altay T
Dermatol Surg 2017 Apr;43(4):583-586. doi: 10.1097/DSS.0000000000001013. PMID: 28002103
Onychomycosis: pathogenesis, diagnosis, and management.
Elewski BE
Clin Microbiol Rev 1998 Jul;11(3):415-29. doi: 10.1128/CMR.11.3.415. PMID: 9665975Free PMC Article

Recent clinical studies

Etiology

Electrodessication Matricectomy With Modified Hyfrecator Tip: Case Series and Literature Review.
Chan J, Pehr K
J Cutan Med Surg 2021 Jul-Aug;25(4):418-423. Epub 2021 Jun 28 doi: 10.1177/12034754211024124. PMID: 34180272
The treatment of onychogryphosis of hand nails by total matricectomy and dorsal V-Y advancement flap.
Gürbüz K
Jt Dis Relat Surg 2020;31(1):39-42. doi: 10.5606/ehc.2020.70611. PMID: 32160492Free PMC Article
Risk Factors and Frequency of Ingrown Nails in Adult Diabetic Patients.
Vural S, Bostanci S, Koçyigit P, Çaliskan D, Baskal N, Aydin N
J Foot Ankle Surg 2018 Mar-Apr;57(2):289-295. Epub 2018 Jan 10 doi: 10.1053/j.jfas.2017.10.006. PMID: 29329712
Total Matricectomy and V-Y Advancement Flap Technique in the Treatment of Onychogryphosis.
Gürbüz K, Ozan F, Kayali C, Altay T
Dermatol Surg 2017 Apr;43(4):583-586. doi: 10.1097/DSS.0000000000001013. PMID: 28002103
Geriatric nail disorders: diagnosis and treatment.
Cohen PR, Scher RK
J Am Acad Dermatol 1992 Apr;26(4):521-31. doi: 10.1016/0190-9622(92)70075-q. PMID: 1597537

Diagnosis

Onychogryphosis: Ram's horn nail.
Srivastava G, Srivastava G
J R Coll Physicians Edinb 2022 Sep;52(3):259. Epub 2022 Sep 15 doi: 10.1177/14782715221126761. PMID: 36369809
Onychogryphosis.
Tosun S, Tosun B
J Am Podiatr Med Assoc 2020 Jul 1;110(4) doi: 10.7547/18-155. PMID: 33021642
Diagnosis using the nail bed and hyponychium.
Perera E, Sinclair R
Dermatol Clin 2015 Apr;33(2):257-63. Epub 2015 Feb 15 doi: 10.1016/j.det.2014.12.006. PMID: 25828715
Congenital malalignment of the big toe nail.
Wagner G, Sachse MM
J Dtsch Dermatol Ges 2012 May;10(5):326-30. Epub 2011 Nov 25 doi: 10.1111/j.1610-0387.2011.07848.x. PMID: 22117849
Congenital onychogryphosis: Leaning Tower nail.
Nath AK, Udayashankar C
Dermatol Online J 2011 Nov 15;17(11):9. PMID: 22136865

Therapy

Haim Munk syndrome: report of two siblings of northern India treated with acitretin.
Mohan RS, Verma S
Indian J Dermatol Venereol Leprol 2011 Mar-Apr;77(2):252. doi: 10.4103/0378-6323.77487. PMID: 21393975
Nail changes and disorders among the elderly.
Singh G, Haneef NS, Uday A
Indian J Dermatol Venereol Leprol 2005 Nov-Dec;71(6):386-92. doi: 10.4103/0378-6323.18941. PMID: 16394478
Matricectomy and nail ablation.
Baran R, Haneke E
Hand Clin 2002 Nov;18(4):693-6, viii; discussion 697. doi: 10.1016/s0749-0712(02)00038-0. PMID: 12516982
Onychogryphosis in elderly persons: an indicator of long-standing poor nursing care? Report of one case and review of the literature.
Möhrenschlager M, Wicke-Wittenius K, Brockow K, Bruckbauer H, Ring J
Cutis 2001 Sep;68(3):233-5. PMID: 11579791
Onychomycosis: pathogenesis, diagnosis, and management.
Elewski BE
Clin Microbiol Rev 1998 Jul;11(3):415-29. doi: 10.1128/CMR.11.3.415. PMID: 9665975Free PMC Article

Prognosis

Electrodessication Matricectomy With Modified Hyfrecator Tip: Case Series and Literature Review.
Chan J, Pehr K
J Cutan Med Surg 2021 Jul-Aug;25(4):418-423. Epub 2021 Jun 28 doi: 10.1177/12034754211024124. PMID: 34180272
Risk Factors and Frequency of Ingrown Nails in Adult Diabetic Patients.
Vural S, Bostanci S, Koçyigit P, Çaliskan D, Baskal N, Aydin N
J Foot Ankle Surg 2018 Mar-Apr;57(2):289-295. Epub 2018 Jan 10 doi: 10.1053/j.jfas.2017.10.006. PMID: 29329712
Total Matricectomy and V-Y Advancement Flap Technique in the Treatment of Onychogryphosis.
Gürbüz K, Ozan F, Kayali C, Altay T
Dermatol Surg 2017 Apr;43(4):583-586. doi: 10.1097/DSS.0000000000001013. PMID: 28002103

Clinical prediction guides

Hair and Nail Conditions: Nail Conditions.
Mervak JE
FP Essent 2022 Jun;517:27-34. PMID: 35679470
Electrodessication Matricectomy With Modified Hyfrecator Tip: Case Series and Literature Review.
Chan J, Pehr K
J Cutan Med Surg 2021 Jul-Aug;25(4):418-423. Epub 2021 Jun 28 doi: 10.1177/12034754211024124. PMID: 34180272
Total Matricectomy and V-Y Advancement Flap Technique in the Treatment of Onychogryphosis.
Gürbüz K, Ozan F, Kayali C, Altay T
Dermatol Surg 2017 Apr;43(4):583-586. doi: 10.1097/DSS.0000000000001013. PMID: 28002103
Onychomycosis caused by Trichosporon mucoides.
Rizzitelli G, Guanziroli E, Moschin A, Sangalli R, Veraldi S
Int J Infect Dis 2016 Jan;42:61-63. Epub 2015 Nov 19 doi: 10.1016/j.ijid.2015.11.011. PMID: 26603646
Geriatric nail disorders: diagnosis and treatment.
Cohen PR, Scher RK
J Am Acad Dermatol 1992 Apr;26(4):521-31. doi: 10.1016/0190-9622(92)70075-q. PMID: 1597537

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