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Early Stage Breast Carcinoma

MedGen UID:
458891
•Concept ID:
C2986665
•
Neoplastic Process
Synonym: Early-Stage Breast Carcinoma

Definition

Breast carcinoma that has not spread beyond the breast and the axillary lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEarly Stage Breast Carcinoma

Professional guidelines

PubMed

Regional nodal recurrence after breast conservation treatment with radiotherapy for women with early-stage breast carcinoma.
Lukens JN, Vapiwala N, Hwang WT, Solin LJ
Int J Radiat Oncol Biol Phys 2009 Apr 1;73(5):1475-81. Epub 2008 Nov 10 doi: 10.1016/j.ijrobp.2008.06.1955. PMID: 19004570
Clinical management of osteoporosis in women with a history of breast carcinoma.
Van Poznak C, Sauter NP
Cancer 2005 Aug 1;104(3):443-56. doi: 10.1002/cncr.21201. PMID: 15968687
The management of early breast carcinoma before and after the introduction of clinical practice guidelines.
White V, Pruden M, Giles G, Collins J, Jamrozik K, Inglis G, Boyages J, Hill D
Cancer 2004 Aug 1;101(3):476-85. doi: 10.1002/cncr.20401. PMID: 15274060

Recent clinical studies

Etiology

Expression of PD-L1 in Early-Stage Invasive Breast Carcinoma and Its Relation to Tumor-Infiltrating Lymphocytes.
Amin NH, Abou-Bakr AA, Eissa S, Nassar HR, Eissa TS, Mohamed G
Asian Pac J Cancer Prev 2022 Mar 1;23(3):1091-1102. doi: 10.31557/APJCP.2022.23.3.1091. PMID: 35345385Free PMC Article
Intraoperative assessment of sentinel lymph nodes in early-stage breast cancer.
Costin AI, Păun I, Vârcuş F, Răcăreanu MM, Lomaca I, Costin AG, Iovan L, Radu L, Mihai GM
Rom J Morphol Embryol 2018;59(4):1033-1039. PMID: 30845281
Risk factors and state-of-the-art indications for boost irradiation in invasive breast carcinoma.
Polo A, Polgár C, Hannoun-Levi JM, Guinot JL, Gutierrez C, Galalae R, van Limbergen E, Strnad V
Brachytherapy 2017 May-Jun;16(3):552-564. Epub 2017 Apr 1 doi: 10.1016/j.brachy.2017.03.003. PMID: 28377213
Lymphatic mapping and sentinel lymph node biopsy in early-stage breast carcinoma: a metaanalysis.
Kim T, Giuliano AE, Lyman GH
Cancer 2006 Jan 1;106(1):4-16. doi: 10.1002/cncr.21568. PMID: 16329134
Local failure and margin status in early-stage breast carcinoma treated with conservation surgery and radiation therapy.
Anscher MS, Jones P, Prosnitz LR, Blackstock W, Hebert M, Reddick R, Tucker A, Dodge R, Leight G Jr, Iglehart JD
Ann Surg 1993 Jul;218(1):22-8. doi: 10.1097/00000658-199307000-00005. PMID: 8328825Free PMC Article

Diagnosis

Early Breast Angiosarcoma Development After Radiotherapy: A Cautionary Tale.
Wei NJJ, Crowley TP, Ragbir M
Ann Plast Surg 2019 Aug;83(2):152-153. doi: 10.1097/SAP.0000000000001856. PMID: 31021840
Intraoperative assessment of sentinel lymph nodes in early-stage breast cancer.
Costin AI, Păun I, Vârcuş F, Răcăreanu MM, Lomaca I, Costin AG, Iovan L, Radu L, Mihai GM
Rom J Morphol Embryol 2018;59(4):1033-1039. PMID: 30845281
A systematic review and meta-analyses of sentinel lymph node identification in breast cancer and melanoma, a plea for tracer mapping.
Niebling MG, Pleijhuis RG, Bastiaannet E, Brouwers AH, van Dam GM, Hoekstra HJ
Eur J Surg Oncol 2016 Apr;42(4):466-73. Epub 2016 Jan 18 doi: 10.1016/j.ejso.2015.12.007. PMID: 26853759
MammoSite.
Keisch M
Expert Rev Med Devices 2005 Jul;2(4):387-94. doi: 10.1586/17434440.2.4.387. PMID: 16293078
The management of early breast carcinoma before and after the introduction of clinical practice guidelines.
White V, Pruden M, Giles G, Collins J, Jamrozik K, Inglis G, Boyages J, Hill D
Cancer 2004 Aug 1;101(3):476-85. doi: 10.1002/cncr.20401. PMID: 15274060

Therapy

Breast-conserving surgery and radiotherapy in early-stage breast cancer: the importance of local control.
Recht A, Solin LJ
Semin Radiat Oncol 2011 Jan;21(1):3-9. doi: 10.1016/j.semradonc.2010.08.001. PMID: 21134648
Minimally-invasive thermal ablation of early-stage breast cancer: a systemic review.
Zhao Z, Wu F
Eur J Surg Oncol 2010 Dec;36(12):1149-55. doi: 10.1016/j.ejso.2010.09.012. PMID: 20889281
Breast cancer sentinel node identification and classification after neoadjuvant chemotherapy-systematic review and meta analysis.
Kelly AM, Dwamena B, Cronin P, Carlos RC
Acad Radiol 2009 May;16(5):551-63. doi: 10.1016/j.acra.2009.01.026. PMID: 19345896
Clinical management of osteoporosis in women with a history of breast carcinoma.
Van Poznak C, Sauter NP
Cancer 2005 Aug 1;104(3):443-56. doi: 10.1002/cncr.21201. PMID: 15968687
The risk of venous thromboembolic disease associated with adjuvant hormone therapy for breast carcinoma: a systematic review.
Deitcher SR, Gomes MP
Cancer 2004 Aug 1;101(3):439-49. doi: 10.1002/cncr.20347. PMID: 15274057

Prognosis

Expression of PD-L1 in Early-Stage Invasive Breast Carcinoma and Its Relation to Tumor-Infiltrating Lymphocytes.
Amin NH, Abou-Bakr AA, Eissa S, Nassar HR, Eissa TS, Mohamed G
Asian Pac J Cancer Prev 2022 Mar 1;23(3):1091-1102. doi: 10.31557/APJCP.2022.23.3.1091. PMID: 35345385Free PMC Article
Intraoperative assessment of sentinel lymph nodes in early-stage breast cancer.
Costin AI, Păun I, Vârcuş F, Răcăreanu MM, Lomaca I, Costin AG, Iovan L, Radu L, Mihai GM
Rom J Morphol Embryol 2018;59(4):1033-1039. PMID: 30845281
Breast-conserving surgery and radiotherapy in early-stage breast cancer: the importance of local control.
Recht A, Solin LJ
Semin Radiat Oncol 2011 Jan;21(1):3-9. doi: 10.1016/j.semradonc.2010.08.001. PMID: 21134648
MammoSite.
Keisch M
Expert Rev Med Devices 2005 Jul;2(4):387-94. doi: 10.1586/17434440.2.4.387. PMID: 16293078
Routine histoprognostic factors in early-stage breast carcinoma: a review.
Gilchrist KW
Cancer Invest 1992;10(6):565-73. doi: 10.3109/07357909209024818. PMID: 1330222

Clinical prediction guides

Prediction of Oncotype DX Recurrence Score by Evaluating the Peritumoral Tumor Budding in Early-stage Breast Carcinoma.
Chu J, DO J, DO SI, Kim HS
Anticancer Res 2023 Dec;43(12):5563-5572. doi: 10.21873/anticanres.16758. PMID: 38030177
Allele-specific copy number analysis of tumors.
Van Loo P, Nordgard SH, Lingjærde OC, Russnes HG, Rye IH, Sun W, Weigman VJ, Marynen P, Zetterberg A, Naume B, Perou CM, Børresen-Dale AL, Kristensen VN
Proc Natl Acad Sci U S A 2010 Sep 28;107(39):16910-5. Epub 2010 Sep 13 doi: 10.1073/pnas.1009843107. PMID: 20837533Free PMC Article
Pathologic examination of the axillary sentinel lymph nodes in patients with early-stage breast carcinoma: current and resolving controversies on the basis of the European Institute of Oncology experience.
Viale G, Mastropasqua MG, Maiorano E, Mazzarol G
Virchows Arch 2006 Mar;448(3):241-7. Epub 2005 Nov 24 doi: 10.1007/s00428-005-0103-3. PMID: 16362823
Lymphatic mapping and sentinel lymph node biopsy in early-stage breast carcinoma: a metaanalysis.
Kim T, Giuliano AE, Lyman GH
Cancer 2006 Jan 1;106(1):4-16. doi: 10.1002/cncr.21568. PMID: 16329134
The management of early breast carcinoma before and after the introduction of clinical practice guidelines.
White V, Pruden M, Giles G, Collins J, Jamrozik K, Inglis G, Boyages J, Hill D
Cancer 2004 Aug 1;101(3):476-85. doi: 10.1002/cncr.20401. PMID: 15274060

Recent systematic reviews

A systematic review and meta-analyses of sentinel lymph node identification in breast cancer and melanoma, a plea for tracer mapping.
Niebling MG, Pleijhuis RG, Bastiaannet E, Brouwers AH, van Dam GM, Hoekstra HJ
Eur J Surg Oncol 2016 Apr;42(4):466-73. Epub 2016 Jan 18 doi: 10.1016/j.ejso.2015.12.007. PMID: 26853759
Minimally-invasive thermal ablation of early-stage breast cancer: a systemic review.
Zhao Z, Wu F
Eur J Surg Oncol 2010 Dec;36(12):1149-55. doi: 10.1016/j.ejso.2010.09.012. PMID: 20889281
Breast cancer sentinel node identification and classification after neoadjuvant chemotherapy-systematic review and meta analysis.
Kelly AM, Dwamena B, Cronin P, Carlos RC
Acad Radiol 2009 May;16(5):551-63. doi: 10.1016/j.acra.2009.01.026. PMID: 19345896
Lymphatic mapping and sentinel lymph node biopsy in early-stage breast carcinoma: a metaanalysis.
Kim T, Giuliano AE, Lyman GH
Cancer 2006 Jan 1;106(1):4-16. doi: 10.1002/cncr.21568. PMID: 16329134
The risk of venous thromboembolic disease associated with adjuvant hormone therapy for breast carcinoma: a systematic review.
Deitcher SR, Gomes MP
Cancer 2004 Aug 1;101(3):439-49. doi: 10.1002/cncr.20347. PMID: 15274057

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