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Epsilon wave

MedGen UID:
1815063
Concept ID:
C5706157
Finding
HPO: HP:0034304

Definition

An electric signal of depolarization observed between the end of the QRS complex and the beginning of the T wave. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpsilon wave

Conditions with this feature

Arrhythmogenic right ventricular dysplasia 9
MedGen UID:
373205
Concept ID:
C1836906
Disease or Syndrome
ARVC may not cause any symptoms in its early stages. However, affected individuals may still be at risk of sudden death, especially during strenuous exercise. When symptoms occur, they most commonly include a sensation of fluttering or pounding in the chest (palpitations), light-headedness, and fainting (syncope). Over time, ARVC can also cause shortness of breath and abnormal swelling in the legs or abdomen. If the myocardium becomes severely damaged in the later stages of the disease, it can lead to heart failure.\n\nArrhythmogenic right ventricular cardiomyopathy (ARVC) is a form of heart disease that usually appears in adulthood. ARVC is a disorder of the myocardium, which is the muscular wall of the heart. This condition causes part of the myocardium to break down over time, increasing the risk of an abnormal heartbeat (arrhythmia) and sudden death.
Arrhythmogenic right ventricular dysplasia 10
MedGen UID:
347543
Concept ID:
C1857777
Disease or Syndrome
ARVC may not cause any symptoms in its early stages. However, affected individuals may still be at risk of sudden death, especially during strenuous exercise. When symptoms occur, they most commonly include a sensation of fluttering or pounding in the chest (palpitations), light-headedness, and fainting (syncope). Over time, ARVC can also cause shortness of breath and abnormal swelling in the legs or abdomen. If the myocardium becomes severely damaged in the later stages of the disease, it can lead to heart failure.\n\nArrhythmogenic right ventricular cardiomyopathy (ARVC) is a form of heart disease that usually appears in adulthood. ARVC is a disorder of the myocardium, which is the muscular wall of the heart. This condition causes part of the myocardium to break down over time, increasing the risk of an abnormal heartbeat (arrhythmia) and sudden death.

Recent clinical studies

Etiology

Olivetti NQS, Sacilotto L, Wulkan F, D'Arezzo Pessente G, Lombardi Peres de Carvalho M, Moleta D, Tessariol Hachul D, Veronese P, Hardy C, Pisani C, Wu TC, Vieira MLC, de França LA, de Souza Freitas M, Rochitte CE, Bueno SC, Bastos Lovisi V, Krieger JE, Scanavacca M, da Costa Pereira A, da Costa Darrieux F
Circ Arrhythm Electrophysiol 2023 Feb;16(2):e011391. Epub 2023 Jan 31 doi: 10.1161/CIRCEP.122.011391. PMID: 36720007
Sevinç Şengül F, Tunca Şahin G, Özgür S, Kafalı HC, Akıncı O, Güzeltaş A, Ergül Y
Anatol J Cardiol 2019 Aug;22(2):60-67. doi: 10.14744/AnatolJCardiol.2019.56985. PMID: 31375646Free PMC Article
Nunes de Alencar Neto J, Baranchuk A, Bayés-Genís A, Bayés de Luna A
Europace 2018 Jun 1;20(FI1):f3-f12. doi: 10.1093/europace/eux202. PMID: 29272363
Gallo C, Blandino A, Giustetto C, Anselmino M, Castagno D, Richiardi E, Gaita F
J Cardiovasc Med (Hagerstown) 2016 Jun;17(6):418-24. doi: 10.2459/JCM.0000000000000354. PMID: 27119598
Francés RJ
Int J Cardiol 2006 Jun 28;110(3):279-87. Epub 2005 Aug 15 doi: 10.1016/j.ijcard.2005.07.004. PMID: 16099519

Diagnosis

Thakur A, Kapil A, Singh S
Eur J Intern Med 2022 Apr;98:107-108. Epub 2022 Jan 10 doi: 10.1016/j.ejim.2022.01.005. PMID: 35027268
Tordini A, Leonelli FM, De Ponti R, Bagliani G, Donzelli S, Lazzari L, Marini C, Pirrami MM, Carreras G
Card Electrophysiol Clin 2019 Jun;11(2):301-314. Epub 2019 Apr 10 doi: 10.1016/j.ccep.2019.02.008. PMID: 31084852
Petrov DB
BMJ 2018 Jun 7;361:k1673. doi: 10.1136/bmj.k1673. PMID: 29880694
Zhang L, Liu L, Kowey PR, Fontaine GH
Curr Cardiol Rev 2014 Aug;10(3):237-45. doi: 10.2174/1573403x10666140514102928. PMID: 24827798Free PMC Article
Caldwell J, Redfearn D, Chiale PA, Baranchuk A
Heart Rhythm 2013 Nov;10(11):1737-8. Epub 2012 Aug 29 doi: 10.1016/j.hrthm.2012.08.038. PMID: 23102627

Therapy

Fontaine GH, Duthoit G, Li G, Andreoletti L, Gandjbakhch E, Frank R
Europace 2017 Jul 1;19(7):1084-1090. doi: 10.1093/europace/euw320. PMID: 28062531
Peters S
Int J Cardiol 2016 Jul 15;215:436-7. Epub 2016 Apr 14 doi: 10.1016/j.ijcard.2016.04.115. PMID: 27131266
Caldwell J, Redfearn D, Chiale PA, Baranchuk A
Heart Rhythm 2013 Nov;10(11):1737-8. Epub 2012 Aug 29 doi: 10.1016/j.hrthm.2012.08.038. PMID: 23102627
Ma KJ, Li N, Wang HT, Chu JM, Fang PH, Yao Y, Ma J, Hua W, Zhang S, Wang FZ, Li Z, Pu JL
Chin Med J (Engl) 2009 May 20;122(10):1133-8. PMID: 19493458
Kiès P, Bootsma M, Bax JJ, Zeppenfeld K, van Erven L, Wijffels MC, van der Wall EE, Schalij MJ
J Cardiovasc Electrophysiol 2006 Jun;17(6):586-93. doi: 10.1111/j.1540-8167.2006.00442.x. PMID: 16836703

Prognosis

Nunes de Alencar Neto J, Baranchuk A, Bayés-Genís A, Bayés de Luna A
Europace 2018 Jun 1;20(FI1):f3-f12. doi: 10.1093/europace/eux202. PMID: 29272363
Fontaine GH, Duthoit G, Li G, Andreoletti L, Gandjbakhch E, Frank R
Europace 2017 Jul 1;19(7):1084-1090. doi: 10.1093/europace/euw320. PMID: 28062531
Saravanan RR, Amuthan V, Janarthanan RA, Balasubramanian S, Mohamed SN
Indian Heart J 2012 Jan-Feb;64(1):84-7. Epub 2012 Mar 26 doi: 10.1016/S0019-4832(12)60017-0. PMID: 22572432Free PMC Article
Al-Hamdi A, Al-Kinani TA, Al-Khafaji AT, Hamed MB, Al-Mayahi MH, Al-Sudani NH
Cardiol J 2010;17(2):172-8. PMID: 20544617
Francés RJ
Int J Cardiol 2006 Jun 28;110(3):279-87. Epub 2005 Aug 15 doi: 10.1016/j.ijcard.2005.07.004. PMID: 16099519

Clinical prediction guides

Platonov PG, Svensson A
Curr Cardiol Rev 2021;17(1):17-23. doi: 10.2174/1573403X16666200810105029. PMID: 32778035Free PMC Article
Nunes de Alencar Neto J, Baranchuk A, Bayés-Genís A, Bayés de Luna A
Europace 2018 Jun 1;20(FI1):f3-f12. doi: 10.1093/europace/eux202. PMID: 29272363
Fontaine GH, Duthoit G, Li G, Andreoletti L, Gandjbakhch E, Frank R
Europace 2017 Jul 1;19(7):1084-1090. doi: 10.1093/europace/euw320. PMID: 28062531
Saravanan RR, Amuthan V, Janarthanan RA, Balasubramanian S, Mohamed SN
Indian Heart J 2012 Jan-Feb;64(1):84-7. Epub 2012 Mar 26 doi: 10.1016/S0019-4832(12)60017-0. PMID: 22572432Free PMC Article
Al-Hamdi A, Al-Kinani TA, Al-Khafaji AT, Hamed MB, Al-Mayahi MH, Al-Sudani NH
Cardiol J 2010;17(2):172-8. PMID: 20544617

Recent systematic reviews

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