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Benign neoplasm of ear

MedGen UID:
138081
•Concept ID:
C0347354
•
Neoplastic Process
Synonyms: Aural Neoplasms, Benign; aural neoplasms, benign; Benign Ear Neoplasm; benign Ear neoplasm; Benign Ear Tumor; benign Ear tumor; benign Ear tumour; Benign Neoplasm of Ear; benign neoplasm of ear; Benign Neoplasm of the Ear; benign neoplasm of the Ear; Benign Tumor of Ear; benign tumor of Ear; Benign Tumor of the Ear; benign tumor of the Ear; benign tumour of Ear; benign tumour of the Ear; ear benign neoplasm
SNOMED CT: Benign neoplasm of ear (255181009)
 
Monarch Initiative: MONDO:0021474

Definition

A neoplasm that arises from the ear and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors.
Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations.
Northrup H, Aronow ME, Bebin EM, Bissler J, Darling TN, de Vries PJ, Frost MD, Fuchs Z, Gosnell ES, Gupta N, Jansen AC, Jóźwiak S, Kingswood JC, Knilans TK, McCormack FX, Pounders A, Roberds SL, Rodriguez-Buritica DF, Roth J, Sampson JR, Sparagana S, Thiele EA, Weiner HL, Wheless JW, Towbin AJ, Krueger DA; International Tuberous Sclerosis Complex Consensus Group
Pediatr Neurol 2021 Oct;123:50-66. Epub 2021 Jul 24 doi: 10.1016/j.pediatrneurol.2021.07.011. PMID: 34399110
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article

Recent clinical studies

Etiology

Postauricular Masses.
Tasli H, Gokgoz MC, Karakoc O
J Craniofac Surg 2020 Sep;31(6):e555-e560. doi: 10.1097/SCS.0000000000006526. PMID: 32604279
Changing nodule on the right helix.
Nguyen CV, Miller DD, Hylwa SA
Int J Dermatol 2017 May;56(5):483-485. Epub 2016 Jun 23 doi: 10.1111/ijd.13354. PMID: 27337342
The Antia-Buch flap revisited.
Tay S, Nikkhah D, Teo TC
Clin Otolaryngol 2017 Aug;42(4):951-953. Epub 2016 Feb 4 doi: 10.1111/coa.12489. PMID: 26108558
Ear canal papillomas.
Abboud O, Saliba I
QJM 2012 Jul;105(7):707-8. Epub 2011 Jul 12 doi: 10.1093/qjmed/hcr103. PMID: 21750024
Electrocochleography.
Kumagami H, Nakata T, Hirano Y, Tsukazaki N
Adv Otorhinolaryngol 1997;53:1-20. doi: 10.1159/000059037. PMID: 9226045

Diagnosis

Squamous cell carcinoma of the external ear.
Chen X, Qiu J
Pan Afr Med J 2023;45:83. Epub 2023 Jun 13 doi: 10.11604/pamj.2023.45.83.38634. PMID: 37663640Free PMC Article
Treatment of pseudocyst of auricle.
Puza C, Nijhawan RI
J Am Acad Dermatol 2023 Dec;89(6):e269-e270. Epub 2022 Feb 11 doi: 10.1016/j.jaad.2022.02.010. PMID: 35151761
Verrucous Spitz Nevus.
Valdivielso-Ramos M, Roldan D, Alonso S
J Pediatr 2020 Nov;226:307-308. Epub 2020 Jul 11 doi: 10.1016/j.jpeds.2020.07.035. PMID: 32663592
Endolymphatic sac tumors.
Wick CC, Manzoor NF, Semaan MT, Megerian CA
Otolaryngol Clin North Am 2015 Apr;48(2):317-30. Epub 2015 Jan 31 doi: 10.1016/j.otc.2014.12.006. PMID: 25650230
Tympanic paraganglioma.
Blake DM, Tomovic S, Jyung RW
Ear Nose Throat J 2014 Apr-May;93(4-5):136, 138. PMID: 24817221

Therapy

Efficacy of acupuncture on cancer pain: A systematic review and meta-analysis.
Faria M, Teixeira M, Pinto MJ, Sargento P
J Integr Med 2024 May;22(3):235-244. Epub 2024 Mar 6 doi: 10.1016/j.joim.2024.03.002. PMID: 38493063
The swollen pinna.
Warner E, Weston C, Barclay-Klingle N, Corbridge R
BMJ 2017 Nov 16;359:j5073. doi: 10.1136/bmj.j5073. PMID: 29146730
Long-term effects of platin and anthracycline derivatives and possible prevention strategies.
Hartmann JT
Front Radiat Ther Oncol 2002;37:92-100. doi: 10.1159/000061304. PMID: 11764674
Bazex syndrome.
Buxtorf K, Hübscher E, Panizzon R
Dermatology 2001;202(4):350-2. doi: 10.1159/000051680. PMID: 11455158
Bleomycin therapy and ototoxicity.
Dal I, Edsmyr F, Stahle J
Acta Otolaryngol 1973 Apr;75(4):323-4. doi: 10.3109/00016487309139733. PMID: 4122085

Prognosis

The swollen pinna.
Warner E, Weston C, Barclay-Klingle N, Corbridge R
BMJ 2017 Nov 16;359:j5073. doi: 10.1136/bmj.j5073. PMID: 29146730
Changing nodule on the right helix.
Nguyen CV, Miller DD, Hylwa SA
Int J Dermatol 2017 May;56(5):483-485. Epub 2016 Jun 23 doi: 10.1111/ijd.13354. PMID: 27337342
Ear canal papillomas.
Abboud O, Saliba I
QJM 2012 Jul;105(7):707-8. Epub 2011 Jul 12 doi: 10.1093/qjmed/hcr103. PMID: 21750024
Intracochlear glandular schwannoma.
Fayad JN, Markaryan A, Linthicum FH Jr, Miyamoto RT
Otolaryngol Head Neck Surg 2011 Jun;144(6):1007-8. Epub 2011 Feb 18 doi: 10.1177/0194599810396799. PMID: 21493356
Bilateral hatchet flaps.
Yu TC, Desciak EB, Eliezri YD
Dermatol Surg 2006 Oct;32(10):1279-82. doi: 10.1111/j.1524-4725.2006.32291.x. PMID: 17034380

Clinical prediction guides

Management and outcome of middle ear adenomatous neuroendocrine tumours: A systematic review.
Engel MSD, van der Lans RJL, Jansen JC, Leemans CR, Bloemena E, Lissenberg-Witte BI, Rijken JA, Smit CF, Hensen EF
Oral Oncol 2021 Oct;121:105465. Epub 2021 Aug 2 doi: 10.1016/j.oraloncology.2021.105465. PMID: 34352556
Ototoxicity and cancer therapy.
Landier W
Cancer 2016 Jun 1;122(11):1647-58. Epub 2016 Feb 9 doi: 10.1002/cncr.29779. PMID: 26859792
Otological toxicity after postoperative radiotherapy for parotid tumours.
Bhide SA, Harrington KJ, Nutting CM
Clin Oncol (R Coll Radiol) 2007 Feb;19(1):77-82. doi: 10.1016/j.clon.2006.11.007. PMID: 17305258
Intralabyrinthine schwannomas.
Neff BA, Willcox TO Jr, Sataloff RT
Otol Neurotol 2003 Mar;24(2):299-307. doi: 10.1097/00129492-200303000-00028. PMID: 12621348
Treatment of carcinoma of the middle ear.
Sinha PP, Aziz HI
Radiology 1978 Feb;126(2):485-7. doi: 10.1148/126.2.485. PMID: 414305

Recent systematic reviews

Efficacy of acupuncture on cancer pain: A systematic review and meta-analysis.
Faria M, Teixeira M, Pinto MJ, Sargento P
J Integr Med 2024 May;22(3):235-244. Epub 2024 Mar 6 doi: 10.1016/j.joim.2024.03.002. PMID: 38493063
Hyperbaric oxygen therapy for late radiation tissue injury.
Lin ZC, Bennett MH, Hawkins GC, Azzopardi CP, Feldmeier J, Smee R, Milross C
Cochrane Database Syst Rev 2023 Aug 15;8(8):CD005005. doi: 10.1002/14651858.CD005005.pub5. PMID: 37585677Free PMC Article
Artificial Intelligence in Head and Neck Cancer: A Systematic Review of Systematic Reviews.
Mäkitie AA, Alabi RO, Ng SP, Takes RP, Robbins KT, Ronen O, Shaha AR, Bradley PJ, Saba NF, Nuyts S, Triantafyllou A, Piazza C, Rinaldo A, Ferlito A
Adv Ther 2023 Aug;40(8):3360-3380. Epub 2023 Jun 8 doi: 10.1007/s12325-023-02527-9. PMID: 37291378Free PMC Article
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
Acute otitis media and antibiotics - a systematic review.
Holm NH, Rusan M, Ovesen T
Dan Med J 2020 Oct 29;67(11) PMID: 33215607

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