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LOC129662195 ReSE screen-validated silencer GRCh37_chr7:156761024-156761215 [ Homo sapiens (human) ]

Gene ID: 129662195, updated on 12-Sep-2024

Summary

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Gene symbol
LOC129662195
Gene description
ReSE screen-validated silencer GRCh37_chr7:156761024-156761215
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region used in a lentiviral ReSE (repressive ability of silencer elements) screen that assays for cell survival based on transcriptional repression of an apoptosis-inducing fusion protein. This region was identified as a functional silencer in HepG2 liver carcinoma cells. [provided by RefSeq, Apr 2023]
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Genomic context

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See LOC129662195 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (156968330..156968521)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (158156163..158156354)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (156761024..156761215)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02-like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:156734117-156734882 Neighboring gene uncharacterized LOC105375605 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:156741558-156742086 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18854 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18855 Neighboring gene nucleolar protein with MIF4G domain 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18856 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:156793008-156793178 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:156795552-156796258 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:156797975-156798627 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18857 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18858 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18859 Neighboring gene MNX1 antisense RNA 2 Neighboring gene motor neuron and pancreas homeobox 1 Neighboring gene MNX1 antisense RNA 1 (head to head)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Systematic identification of silencers in human cells. Pang B, et al. Nat Genet, 2020 Mar. PMID 32094911, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_159231.1 

    Range
    101..292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    156968330..156968521
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    158156163..158156354
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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