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LOC127830462 OCT4-NANOG hESC enhancer GRCh37_chr15:82559427-82559987 [ Homo sapiens (human) ]

Gene ID: 127830462, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127830462
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr15:82559427-82559987
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127830462 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (82267086..82267646)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (80131203..80131763)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (82559427..82559987)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370924 Neighboring gene long intergenic non-protein coding RNA 1583 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr15:82392793-82393305 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6747 Neighboring gene elongation factor like GTPase 1 Neighboring gene RNA, U1 small nuclear 77, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9960 Neighboring gene MPRA-validated peak2402 silencer Neighboring gene ReSE screen-validated silencer GRCh37_chr15:82553005-82553191 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9961 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9962 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9963 Neighboring gene stabilizer of axonemal microtubules 2 Neighboring gene ADAMTS7 pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:82611132-82611632 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:82611633-82612133 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:82621782-82622282 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:82622283-82622783 Neighboring gene dynamin 1 pseudogene 43

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_131944.1 

    Range
    101..661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    82267086..82267646
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    80131203..80131763
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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