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LOC127397966 H3K27ac hESC enhancer GRCh37_chr3:71193639-71194138 [ Homo sapiens (human) ]

Gene ID: 127397966, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127397966
Gene description
H3K27ac hESC enhancer GRCh37_chr3:71193639-71194138
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127397966 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (71144488..71144987)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (71181059..71181558)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (71193639..71194138)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:70882268-70882846 Neighboring gene RNA, U6 small nuclear 281, pseudogene Neighboring gene MED14-independent group 3 enhancer GRCh37_chr3:70902705-70903904 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:70903859-70904359 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:70926235-70926734 Neighboring gene OCT4 hESC enhancer GRCh37_chr3:70976354-70976889 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:70998543-70998739 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:71012492-71013094 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr3:71025197-71026396 Neighboring gene VISTA enhancer hs864 Neighboring gene forkhead box P1 Neighboring gene VISTA enhancer hs965 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:71114251-71114751 Neighboring gene uncharacterized LOC124906247 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr3:71128185-71128767 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20059 Neighboring gene VISTA enhancer hs1092 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:71178876-71179618 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:71205831-71206536 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:71214878-71215027 Neighboring gene NANOG hESC enhancer GRCh37_chr3:71259322-71259867 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:71275618-71276118 Neighboring gene VISTA enhancer hs630 Neighboring gene VISTA enhancer hs187 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:71354949-71355604 Neighboring gene FOXP1 antisense RNA 1 Neighboring gene uncharacterized LOC124906248

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_099935.1 

    Range
    101..600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    71144488..71144987
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    71181059..71181558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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