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LOC127272664 H3K4me1 hESC enhancer GRCh37_chr2:16174407-16174907 [ Homo sapiens (human) ]

Gene ID: 127272664, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127272664
Gene description
H3K4me1 hESC enhancer GRCh37_chr2:16174407-16174907
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127272664 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (16034285..16034785)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (16065848..16066348)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (16174407..16174907)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:16080270-16080800 Neighboring gene MYCN opposite strand Neighboring gene RNA, 7SL, cytoplasmic 104, pseudogene Neighboring gene MYCN proto-oncogene, bHLH transcription factor Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:16120447-16121234 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:16140957-16141151 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:16153570-16154181 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15348 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:16197762-16198262 Neighboring gene gastric cancer associated transcript 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:16243116-16243946 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:16245136-16246335 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:16349737-16350342 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:16367293-16367949 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:16378022-16379221 Neighboring gene uncharacterized LOC124900535

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_094515.1 

    Range
    101..601
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    16034285..16034785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    16065848..16066348
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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