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Mir3474 microRNA 3474 [ Mus musculus (house mouse) ]

Gene ID: 100499529, updated on 17-Aug-2024

Summary

Official Symbol
Mir3474provided by MGI
Official Full Name
microRNA 3474provided by MGI
Primary source
MGI:MGI:4441441
See related
Ensembl:ENSMUSG00000093120 miRBase:MI0014707; AllianceGenome:MGI:4441441
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mir-3474; mmu-mir-3474
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See Mir3474 in Genome Data Viewer
Location:
2 H1; 2 78.72 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (158480503..158480560)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (158638583..158638640)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 40 Neighboring gene predicted gene 14204 Neighboring gene STARR-positive B cell enhancer ABC_E4515 Neighboring gene solute carrier family 32 (GABA vesicular transporter), member 1 Neighboring gene ARP5 actin-related protein 5 Neighboring gene STARR-positive B cell enhancer ABC_E10158 Neighboring gene STARR-positive B cell enhancer ABC_E7879 Neighboring gene STARR-positive B cell enhancer mm9_chr2:158499319-158499620 Neighboring gene protein phosphatase 1, regulatory subunit 16B Neighboring gene STARR-positive B cell enhancer ABC_E2650 Neighboring gene STARR-positive B cell enhancer ABC_E7880 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:158548828-158549026 Neighboring gene STARR-positive B cell enhancer ABC_E2056 Neighboring gene STARR-positive B cell enhancer ABC_E7881 Neighboring gene STARR-positive B cell enhancer ABC_E416 Neighboring gene family with sequence similarity 83, member D

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037312.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AL663091
    Related
    ENSMUST00000175379.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    158480503..158480560
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)