Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Mar 19;22(3):e17026.
doi: 10.2196/17026.

An Analysis of the Learning Health System in Its First Decade in Practice: Scoping Review

Affiliations

An Analysis of the Learning Health System in Its First Decade in Practice: Scoping Review

Jodyn E Platt et al. J Med Internet Res. .

Abstract

Background: In the past decade, Lynn Etheredge presented a vision for the Learning Health System (LHS) as an opportunity for increasing the value of health care via rapid learning from data and immediate translation to practice and policy. An LHS is defined in the literature as a system that seeks to continuously generate and apply evidence, innovation, quality, and value in health care.

Objective: This review aimed to examine themes in the literature and rhetoric on the LHS in the past decade to understand efforts to realize the LHS in practice and to identify gaps and opportunities to continue to take the LHS forward.

Methods: We conducted a thematic analysis in 2018 to analyze progress and opportunities over time as compared with the initial Knowledge Gaps and Uncertainties proposed in 2007.

Results: We found that the literature on the LHS has increased over the past decade, with most articles focused on theory and implementation; articles have been increasingly concerned with policy.

Conclusions: There is a need for attention to understanding the ethical and social implications of the LHS and for exploring opportunities to ensure that these implications are salient in implementation, practice, and policy efforts.

Keywords: bioethics; health information exchange; knowledge management; learning health system; review.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure 1
Figure 1
Areas critical to the realization of a learning health system.
Figure 2
Figure 2
Summary of search strategy and themes.
Figure 3
Figure 3
Frequency of articles published by year (n=542).
Figure 4
Figure 4
Trends in article categories among frequently cited articles based on review of frequently cited articles (n=85).

Similar articles

Cited by

References

    1. Etheredge LM. A rapid-learning health system. Health Aff (Millwood) 2007;26(2):w107–18. doi: 10.1377/hlthaff.26.2.w107. - DOI - PubMed
    1. Olsen L, Aisner D, McGinnis JM, Roundtable on Evidence-Based Medicine. Institute of Medicine . The Learning Healthcare System: Workshop Summary. Washington, DC: National Academies Press; 2007. - PubMed
    1. Dean BB, Lam J, Natoli JL, Butler Q, Aguilar D, Nordyke RJ. Review: use of electronic medical records for health outcomes research: a literature review. Med Care Res Rev. 2009 Dec;66(6):611–38. doi: 10.1177/1077558709332440. - DOI - PubMed
    1. Treweek S, Mitchell E, Pitkethly M, Cook J, Kjeldstrøm M, Taskila T, Johansen M, Sullivan F, Wilson S, Jackson C, Jones R. Strategies to improve recruitment to randomised controlled trials. Cochrane Database Syst Rev. 2010 Jan 20;(1):MR000013. doi: 10.1002/14651858.MR000013.pub4. - DOI - PubMed
    1. Swan M. Emerging patient-driven health care models: an examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health. 2009 Feb;6(2):492–525. doi: 10.3390/ijerph6020492. http://www.mdpi.com/resolver?pii=ijerph6020492 - DOI - PMC - PubMed

Publication types

MeSH terms