Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jul:112:233-6.
doi: 10.1016/j.fitote.2016.06.012. Epub 2016 Jun 21.

Caesalpinone A, a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, from the pods of Caesalpinia spinosa Kuntze

Weihua Mu  1 , Hongbo Tang  1 , Yuanping Li  1 , Dongyang He  1 , Ruijing Ma  1 , Liqin Wang  2
Affiliations

Caesalpinone A, a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, from the pods of Caesalpinia spinosa Kuntze

Weihua Mu et al. Fitoterapia. 2016 Jul.

Abstract

Caesalpinone A (1), a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, along with ten known sesquiterpenoids (2-11) were isolated from the pods of Caesalpinia spinosa Kuntze (Tara). The structure of caesalpinone A was elucidated based on its 1D and 2D NMR spectra. The absolute configuration of 1 was assigned by the comparison of the experimental and calculated electronic circular dichroism spectra. Compound 1 was evaluated for the inhibitory activities against five human tumor cell lines. The sesquiterpenoids of isodaucane skeleton and caryolane skeleton were isolated from Caesalpinia genus for the first time. Compounds 5-9 were firstly reported from Tara.

Keywords: Caesalpinia spinosa; Caesalpinone A; Sesquiterpenoid; Tara.

PubMed Disclaimer

Similar articles

See all similar articles

LinkOut - more resources