Case Reports
doi: 10.1016/j.pediatrneurol.2010.12.009.
MPPH syndrome: two new cases
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- PMID: 21481746
- DOI: 10.1016/j.pediatrneurol.2010.12.009
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Case Reports
MPPH syndrome: two new cases
Pediatr Neurol.
2011 May.
Abstract
This report describes 2 additional cases of megalencephaly and perisylvian polymicrogyria with postaxial polydactyly and hydrocephalus syndrome, a recently recognized disorder of infants and young children with macrocrania, developmental delay/mental retardation, and often epilepsy. Medulloblastoma, a previously unreported feature in megalencephaly and perisylvian polymicrogyria with postaxial polydactyly and hydrocephalus syndrome, developed in one child at 3 years of age. Although the disorder is presumed to be genetic, the cause of megalencephaly and perisylvian polymicrogyria with postaxial polydactyly and hydrocephalus syndrome has not yet been determined.
Copyright © 2011 Elsevier Inc. All rights reserved.
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