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Randomized Controlled Trial
. 2008 Dec;35(6):568-71.
doi: 10.1016/j.amepre.2008.06.034.

Computerized counseling for folate knowledge and use: a randomized controlled trial

Eleanor Bimla Schwarz  1 , Mindy Sobota, Ralph Gonzales, Barbara Gerbert
Affiliations
Randomized Controlled Trial

Computerized counseling for folate knowledge and use: a randomized controlled trial

Eleanor Bimla Schwarz et al. Am J Prev Med. 2008 Dec.

Abstract

Background: Periconception folate supplementation significantly reduces the risk of neural-tube defects, but few U.S. women start folate supplementation before pregnancy, and the amount of clinician time available to counsel patients about folate is limited. This study evaluated whether computer-assisted counseling and the provision of free folate tablets increases women's knowledge and use of folate supplements.

Design: Randomized controlled trial; follow-up began 6 months after enrollment and was completed on average 7 months after enrollment.

Setting/participants: A total of 446 women, aged 18-45 years, were recruited from two urgent care clinics in San Francisco from March to July 2005 (data collection was completed in 2006; data were analyzed in 2007).

Intervention: Participants received a 15-minute computerized educational session and 200 folate tablets.

Main outcome measures: The primary outcome was the knowledge that folate can prevent birth defects; secondary outcomes included the self-reported use of a folate supplement at follow-up.

Results: At follow-up, women in the intervention group were more likely to know that folate prevents birth defects (46% vs 27%, relative risk [RR]=1.72, 95% CI=1.32, 2.23); to know that folate is most important in early pregnancy (36% vs 17%, RR=2.11, 95% CI=1.50, 2.97); and to report the recent use of a folate supplement (32% vs 21%, RR=1.54, 95% CI=1.12, 2.13).

Conclusions: A one-time, brief, computerized counseling session about folate with the provision of free folate tablets increased the knowledge and use of folate supplements among women > or =6 months later.

Trial registration: NCT00177515.

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Flow of participants through trial
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