{"id":14345,"date":"2025-01-10T10:45:37","date_gmt":"2025-01-10T15:45:37","guid":{"rendered":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/?p=14345"},"modified":"2025-01-10T10:45:37","modified_gmt":"2025-01-10T15:45:37","slug":"refseq-release-228","status":"publish","type":"post","link":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/","title":{"rendered":"RefSeq Release 228 is Available!"},"content":{"rendered":"<p>Check out RefSeq release 228, now available <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/refseq\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">online<\/a>\u00a0and from the\u00a0<a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/refseq\/release\/\">FTP<\/a>\u00a0site. You can access RefSeq data through\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-227-20241113\">NCBI Datasets<\/a>. The release is provided in several directories as a complete dataset and also as divided by logical groupings.<\/p>\n<h5>What\u2019s included in this release?<\/h5>\n<p>As of January 3, 2025, this full release incorporates genomic, transcript, and protein data containing:<\/p>\n<ul>\n<li><span style=\"font-size: 17px;\">513,096,240 records, including<\/span><\/li>\n<li><span style=\"font-size: 17px;\">391,903,900 proteins<\/span><\/li>\n<li><span style=\"font-size: 17px;\">67,997,702 RNAs<\/span><\/li>\n<li><span style=\"font-size: 17px;\">Sequences from 162,138 organisms\u00a0<\/span><\/li>\n<\/ul>\n<p><!--more--><\/p>\n<h5><b>New horse and donkey assemblies and annotations<\/b><\/h5>\n<p>Horse Annotation Release <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_041296265.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">GCF_041296265.1-RS_2024_12<\/a> contains the annotated genes, transcripts, and proteins in a new phased haploid assembly of a Thoroughbred derived haplotype. Learn more in the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/refseq\/annotation_euk\/Equus_caballus\/GCF_041296265.1-RS_2024_12\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">annotation report<\/a>.\u00a0The annotation products are available in the sequence databases and on the <a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/genomes\/all\/annotation_releases\/9796\/GCF_041296265.1-RS_2024_12\/\">FTP site<\/a>.<\/p>\n<p>Donkey Annotation Release <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_041296235.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">GCF_041296235.1-RS_2024_12<\/a> contains the annotated genes, transcripts, and proteins in a new phased haploid assembly of the Thoroughbred horse dam and the donkey sire haplotype from a mule. Learn more in the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/refseq\/annotation_euk\/Equus_asinus\/GCF_041296235.1-RS_2024_12\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">annotation report<\/a>. The annotation products are available in the sequence databases and on the <a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/genomes\/all\/annotation_releases\/9793\/GCF_041296235.1-RS_2024_12\/\">FTP site<\/a>.<\/p>\n<h5><b>New eukaryotic genome annotations<\/b><\/h5>\n<p>This release contains new or updated annotations generated by NCBI\u2019s eukaryotic genome annotation pipeline for 38 species, including:<\/p>\n<ul>\n<li><span style=\"font-size: 17px;\">Rabbit, based on new assembly mOryCun1.1 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_964237555.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">GCF_964237555.1-RS_2024_11<\/a>) <em>(pictured)<\/em><\/span><\/li>\n<li><span style=\"font-size: 17px;\">White-tailed deer, based on updated assembly Ovbor_1.2 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_023699985.2\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">GCF_023699985.2-RS_2024_12<\/a>)<\/span><\/li>\n<li><span style=\"font-size: 17px;\">Merriam&#8217;s kangaroo rat, based on new assembly mDipMer1.0.p (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/taxonomy\/94247\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">GCF_024711535.1-RS_2024_11<\/a>)<\/span><\/li>\n<li><span style=\"font-size: 17px;\">Axolotl, based on new assembly UKY_AmexF1_1 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_040938575.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">GCF_040938575.1-RS_2024_10<\/a>)<\/span><\/li>\n<li><span style=\"font-size: 17px;\">American cockroach, based on new assembly P.americana_PAMFEO1_priV1 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_040183065.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">GCF_040183065.1-RS_2024_10<\/a>)<\/span><\/li>\n<li><span style=\"font-size: 17px;\">Wood tobacco, based on updated assembly ASM39365v2 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_000393655.2\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">GCF_000393655.2-RS_2024_11<\/a>)<\/span><\/li>\n<\/ul>\n<h5><b>Upcoming changes to NCBI Taxonomy for viruses (Spring 2025)<\/b><\/h5>\n<p>As <a href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/12\/11\/ncbi-taxonomy-changes-to-viruses\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-228-20250110\">previously mentioned<\/a>, NCBI will add binomial species names to about 3000 viruses to reflect\u202fchanges to the\u202fInternational Code of Virus Classification and Nomenclature\u202f(ICVCN).<\/p>\n<h4>Stay up to date<\/h4>\n<p>RefSeq is part of the\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/comparative-genomics-resource\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-227-20241113\">NIH Comparative Genomics Resource (CGR)<\/a>.\u00a0<span data-contrast=\"none\">CGR facilitates reliable comparative genomics analyses\u202ffor all eukaryotic organisms through an NCBI Toolkit and community collaboration.\u00a0<\/span><span class=\"TextRun Highlight SCXW148001688 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW148001688 BCX8\">Follow us on social\u202f<\/span><\/span><a class=\"Hyperlink SCXW148001688 BCX8\" href=\"https:\/\/twitter.com\/ncbi\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"TextRun Highlight SCXW148001688 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW148001688 BCX8\" data-ccp-charstyle=\"Hyperlink\">@NCBI<\/span><\/span><\/a>\u00a0and\u00a0<a class=\"external-link\" href=\"https:\/\/public.govdelivery.com\/accounts\/USNLMOCPL\/subscriber\/new?topic_id=USNLMOCPL_50%22\" rel=\"nofollow\">join our mailing list<\/a>\u00a0to keep up to date with RefSeq and other CGR news.<\/p>\n<h4>Questions?<\/h4>\n<p><span data-contrast=\"auto\">If you have questions or would like to provide feedback, please\u00a0<a href=\"https:\/\/support.nlm.nih.gov\/support\/create-case\/\">reach out<\/a>\u00a0to us!<\/span><span data-contrast=\"auto\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Check out RefSeq release 228, now available online\u00a0and from the\u00a0FTP\u00a0site. You can access RefSeq data through\u00a0NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings. What\u2019s included in this release? As of January 3, 2025, this full release incorporates genomic, transcript, and protein data containing: &hellip; <a href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">RefSeq Release 228 is Available!<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":42204617,"featured_media":14360,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"RefSeq Release 228 is Available!","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2248],"tags":[693060768,574294629,693060836,27739816],"table_tags":[],"class_list":["post-14345","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-whats-new","tag-comparative-genomics-resource-cgr","tag-eukaryotic-genome-annotation","tag-ncbi-datasets","tag-refseq"],"jetpack_publicize_connections":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>RefSeq Release 228 is Available! - NCBI Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"RefSeq Release 228 is Available! - NCBI Insights\" \/>\n<meta property=\"og:description\" content=\"Check out RefSeq release 228, now available online\u00a0and from the\u00a0FTP\u00a0site. You can access RefSeq data through\u00a0NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings. What\u2019s included in this release? As of January 3, 2025, this full release incorporates genomic, transcript, and protein data containing: &hellip; Continue reading RefSeq Release 228 is Available! &rarr;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/\" \/>\n<meta property=\"og:site_name\" content=\"NCBI Insights\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ncbi.nlm\" \/>\n<meta property=\"article:published_time\" content=\"2025-01-10T15:45:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2025\/01\/iStock-1360438569-e1736522576930.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1100\" \/>\n\t<meta property=\"og:image:height\" content=\"733\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"NCBI Staff\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@NCBI\" \/>\n<meta name=\"twitter:site\" content=\"@NCBI\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"NCBI Staff\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/\"},\"author\":{\"name\":\"NCBI Staff\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/#\/schema\/person\/4f41ea6a31cea38a9a1b1419c048e50b\"},\"headline\":\"RefSeq Release 228 is Available!\",\"datePublished\":\"2025-01-10T15:45:37+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/\"},\"wordCount\":353,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/#organization\"},\"image\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2025\/01\/iStock-1360438569-e1736522576930.jpg?fit=1100%2C733&ssl=1\",\"keywords\":[\"Comparative Genomics Resource (CGR)\",\"Eukaryotic genome annotation\",\"NCBI Datasets\",\"RefSeq\"],\"articleSection\":[\"What's New\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/\",\"url\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/\",\"name\":\"RefSeq Release 228 is Available! - NCBI Insights\",\"isPartOf\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2025\/01\/iStock-1360438569-e1736522576930.jpg?fit=1100%2C733&ssl=1\",\"datePublished\":\"2025-01-10T15:45:37+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2025\/01\/10\/refseq-release-228\/#primaryimage\",\"url\":\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2025\/01\/iStock-1360438569-e1736522576930.jpg?fit=1100%2C733&ssl=1\",\"contentUrl\":\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2025\/01\/iStock-1360438569-e1736522576930.jpg?fit=1100%2C733&ssl=1\",\"width\":1100,\"height\":733,\"caption\":\"Large rabbit close-up sits on the right of the frame. 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