{"id":14263,"date":"2024-12-18T10:53:08","date_gmt":"2024-12-18T15:53:08","guid":{"rendered":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/?p=14263"},"modified":"2024-12-18T10:53:08","modified_gmt":"2024-12-18T15:53:08","slug":"ncbi-hidden-markov-models-release-17-0","status":"publish","type":"post","link":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/12\/18\/ncbi-hidden-markov-models-release-17-0\/","title":{"rendered":"Now Available! NCBI Hidden Markov Models (HMM) Release 17.0"},"content":{"rendered":"<p><a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/hmm\/17.0\/\">Download release 17.0<\/a>\u00a0of the NCBI protein profile Hidden Markov models (HMMs) used by the\u00a0<a class=\"external-link\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/refseq\/annotation_prok\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=hmm-release-17-20241218\" target=\"_blank\" rel=\"nofollow noopener\">Prokaryotic Genome Annotation Pipeline (PGAP)<\/a>. Search this collection against your favorite prokaryotic proteins to identify their function using the <a class=\"external-link\" href=\"http:\/\/eddylab.org\/software\/hmmer\/Userguide.pdf\" target=\"_blank\" rel=\"nofollow noopener\">HMMER sequence analysis package<\/a>.<\/p>\n<h5>What\u2019s New?<\/h5>\n<p>Release 17.0 contains:<\/p>\n<ul>\n<li><span style=\"font-size: 17px;\">17,433 HMMs maintained by NCBI<\/span><\/li>\n<li><span style=\"font-size: 17px;\">386 new HMMs since release 16.0<\/span><\/li>\n<\/ul>\n<p><!--more--><\/p>\n<p>You can search and view the details for these in the\u00a0<a class=\"external-link\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/protfam?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=hmm-release-17-20241218\" target=\"_blank\" rel=\"nofollow noopener\">Protein Family Model<\/a>\u00a0collection, which also includes conserved domain architectures and BlastRules, and access all\u00a0<a class=\"external-link\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/refseq\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=hmm-release-17-20241218\" target=\"_blank\" rel=\"nofollow noopener\">RefSeq<\/a>\u00a0proteins that these models name.<\/p>\n<h5>Stay up to date<\/h5>\n<p><span data-contrast=\"auto\">Follow us on social\u202f<\/span><a href=\"https:\/\/twitter.com\/ncbi\"><span data-contrast=\"auto\">@NCBI<\/span><\/a><span data-contrast=\"auto\">\u202fand\u202f<\/span><a href=\"https:\/\/public.govdelivery.com\/accounts\/USNLMOCPL\/subscriber\/new?topic_id=USNLMOCPL_52\"><span data-contrast=\"auto\">join our mailing list<\/span><\/a><span data-contrast=\"auto\">\u202fto keep up to date with\u202fHMM\u202fand other NCBI news.\u202f\u202f<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335559738&quot;:150,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h5>We want to hear from you!<\/h5>\n<p><span data-contrast=\"auto\">If you have questions or would like to provide feedback, please reach out to us at <a href=\"mailto:info@ncbi.nlm.nih.gov\">info@ncbi.nlm.nih.gov<\/a>.<\/span><\/p>\n<div class=\"sharedaddy sd-sharing-enabled\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Download release 17.0\u00a0of the NCBI protein profile Hidden Markov models (HMMs) used by the\u00a0Prokaryotic Genome Annotation Pipeline (PGAP). Search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package. What\u2019s New? Release 17.0 contains: 17,433 HMMs maintained by NCBI 386 new HMMs since release 16.0<\/p>\n","protected":false},"author":42204617,"featured_media":14267,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"Now Available! NCBI Hidden Markov Models (HMM) Release 17.0","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2248],"tags":[693060700,693060701,693060702,27739816],"table_tags":[],"class_list":["post-14263","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-whats-new","tag-hidden-markov-models-hmm","tag-hmmer","tag-protein-family-model","tag-refseq"],"jetpack_publicize_connections":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Now Available! 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Release 17.0 contains: 17,433 HMMs maintained by NCBI 386 new HMMs since release 16.0\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/12\/18\/ncbi-hidden-markov-models-release-17-0\/\" \/>\n<meta property=\"og:site_name\" content=\"NCBI Insights\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ncbi.nlm\" \/>\n<meta property=\"article:published_time\" content=\"2024-12-18T15:53:08+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/12\/HMM_Release-9-e1734462625364.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1100\" \/>\n\t<meta property=\"og:image:height\" content=\"575\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"NCBI Staff\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@NCBI\" \/>\n<meta name=\"twitter:site\" content=\"@NCBI\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"NCBI Staff\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/12\/18\/ncbi-hidden-markov-models-release-17-0\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/12\/18\/ncbi-hidden-markov-models-release-17-0\/\"},\"author\":{\"name\":\"NCBI Staff\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/#\/schema\/person\/4f41ea6a31cea38a9a1b1419c048e50b\"},\"headline\":\"Now Available! 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