{"id":12972,"date":"2024-03-11T15:13:45","date_gmt":"2024-03-11T19:13:45","guid":{"rendered":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/?p=12972"},"modified":"2024-03-11T15:21:24","modified_gmt":"2024-03-11T19:21:24","slug":"now-available-refseq-release-223","status":"publish","type":"post","link":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/03\/11\/now-available-refseq-release-223\/","title":{"rendered":"Now Available: RefSeq Release 223"},"content":{"rendered":"<p>Check out RefSeq release 223, now available <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/refseq\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">online<\/a>\u00a0and from the\u00a0<a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/refseq\/release\/\">FTP<\/a>\u00a0site. You can access RefSeq data through\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">NCBI Datasets<\/a>.<\/p>\n<h5>What\u2019s included in this release?<\/h5>\n<p>As of March 4, 2024, this full release incorporates genomic, transcript, and protein data containing:<\/p>\n<ul>\n<li><span style=\"font-size: 17px;\">425,594,654 records<\/span><\/li>\n<li><span style=\"font-size: 17px;\">316,329,937 proteins<\/span><\/li>\n<li><span style=\"font-size: 17px;\">60,886,133 RNAs<\/span><\/li>\n<li><span style=\"font-size: 17px;\">sequences from 147,591 organisms\u00a0<\/span><\/li>\n<\/ul>\n<p><!--more--><\/p>\n<p>The release is provided in several directories as a complete dataset and divided by logical groupings.<\/p>\n<h5><b>New rat assembly and annotation<\/b><\/h5>\n<p>The Genome Reference Consortium has released a new rat assembly, <a href=\"https:\/\/genomeref.blogspot.com\/2024\/02\/grcr8-new-rat-reference-assembly-is.html\">GRCr8<\/a>. Annotation Release <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genome\/annotation_euk\/Rattus_norvegicus\/GCF_036323735.1-RS_2024_02\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">GCF_036323735.1-RS_2024_02<\/a> contains the annotated genes, transcripts and proteins in the new assembly. Curated RefSeq Select transcripts are available for 80% of protein-coding genes. The annotation products are available in the sequence databases and on the <a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/genomes\/all\/annotation_releases\/10116\/GCF_036323735.1-RS_2024_02\/\">FTP site<\/a>.<\/p>\n<h5><b>Updated mouse genome annotation\u00a0<\/b><\/h5>\n<p>Annotation Release <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genome\/annotation_euk\/Mus_musculus\/GCF_000001635.27-RS_2024_02\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">GCF_000001635.27-RS_2024_02<\/a> is an update of NCBI Mus musculus Annotation Release 109. The annotation products are available in the sequence databases and on the <a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/genomes\/all\/annotation_releases\/10090\/GCF_000001635.27-RS_2024_02\/\">FTP site<\/a>.<\/p>\n<h5><b>Annotation of the Asian tiger mosquito<\/b><\/h5>\n<p>Annotation release <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genome\/annotation_euk\/Aedes_albopictus\/GCF_035046485.1-RS_2024_01\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">GCF_035046485.1-RS_2024_01<\/a> is now available for Aedes albopictus (Asian tiger mosquito) assembly, AalbF5. The annotation products are available in the sequence databases and on the <a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/genomes\/all\/annotation_releases\/7160\/GCF_035046485.1-RS_2024_01\/\">FTP site<\/a>.<\/p>\n<h5>New eukaryotic genome annotations<\/h5>\n<p>This release includes new annotations generated by NCBI&#8217;s eukaryotic genome annotation pipeline for 36 additional species, including:<\/p>\n<ul>\n<li><span style=\"font-size: 17px;\">Guinea pig, based on new assembly mCavPor4.1 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_034190915.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">GCF_034190915.1-RS_2024_02<\/a>)<\/span><\/li>\n<li><span style=\"font-size: 17px;\">Philippine flying lemur, based on new assembly mCynVol1.pri (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_027409185.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">GCF_027409185.1-RS_2024_02<\/a>)<\/span><\/li>\n<li><span style=\"font-size: 17px;\">Song sparrow, based on new assembly bMelMel2.pri (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_035770615.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">GCF_035770615.1-RS_2024_02<\/a>)<\/span><\/li>\n<li><span style=\"font-size: 17px;\">Domestic silkworm, based on new assembly ASM3026992v2 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_030269925.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">GCF_030269925.1-RS_2024_01<\/a>)<\/span><\/li>\n<li><span style=\"font-size: 17px;\">Japanese rose (<em>Rosa rugosa<\/em>), based on new assembly drRosRugo1.1 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/GCF_958449725.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">GCF_958449725.1-RS_2024_01<\/a>) <em>(pictured)<\/em><\/span><\/li>\n<\/ul>\n<h5><b>Human alignment files archived on the FTP site<\/b><\/h5>\n<p>The alignments in <a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/refseq\/H_sapiens\/alignments\/\">this directory<\/a> are no longer being updated but are provided for archival purposes. Users interested in the latest set of alignments of human RefSeq transcripts to the genome should use the files located in the <a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/refseq\/H_sapiens\/historical\">historical directory<\/a>.<\/p>\n<h4>Stay up to date<\/h4>\n<p>RefSeq is part of the\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/comparative-genomics-resource\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-223-20240311\">NIH Comparative Genomics Resource (CGR)<\/a>.\u00a0<span data-contrast=\"none\">CGR facilitates reliable comparative genomics analyses\u202ffor all eukaryotic organisms through an NCBI Toolkit and community collaboration.\u00a0<\/span><span class=\"TextRun Highlight SCXW148001688 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW148001688 BCX8\">Follow us on social\u202f<\/span><\/span><a class=\"Hyperlink SCXW148001688 BCX8\" href=\"https:\/\/twitter.com\/ncbi\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"TextRun Highlight SCXW148001688 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW148001688 BCX8\" data-ccp-charstyle=\"Hyperlink\">@NCBI<\/span><\/span><\/a>\u00a0and\u00a0<a class=\"external-link\" href=\"https:\/\/public.govdelivery.com\/accounts\/USNLMOCPL\/subscriber\/new?topic_id=USNLMOCPL_50%22\" rel=\"nofollow\">join our mailing list<\/a>\u00a0to keep up to date with RefSeq and other CGR news.<\/p>\n<h4>Questions?<\/h4>\n<p><span data-contrast=\"auto\">If you have questions or would like to provide feedback, please\u00a0<a href=\"https:\/\/support.nlm.nih.gov\/support\/create-case\/\">reach out<\/a>\u00a0to us!<\/span><span data-contrast=\"auto\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Check out RefSeq release 223, now available online\u00a0and from the\u00a0FTP\u00a0site. You can access RefSeq data through\u00a0NCBI Datasets. What\u2019s included in this release? As of March 4, 2024, this full release incorporates genomic, transcript, and protein data containing: 425,594,654 records 316,329,937 proteins 60,886,133 RNAs sequences from 147,591 organisms\u00a0<\/p>\n","protected":false},"author":42204617,"featured_media":12995,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"RefSeq Release 223","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2248],"tags":[693060768,693060851,574294629,27739816],"table_tags":[],"class_list":["post-12972","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-whats-new","tag-comparative-genomics-resource-cgr","tag-eukaryote-genome-annotation-pipeline-egap","tag-eukaryotic-genome-annotation","tag-refseq"],"jetpack_publicize_connections":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Now Available: RefSeq Release 223 - NCBI Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/03\/11\/now-available-refseq-release-223\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Now Available: RefSeq Release 223 - NCBI Insights\" \/>\n<meta property=\"og:description\" content=\"Check out RefSeq release 223, now available online\u00a0and from the\u00a0FTP\u00a0site. You can access RefSeq data through\u00a0NCBI Datasets. What\u2019s included in this release? 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