{"id":11588,"date":"2023-06-12T12:33:44","date_gmt":"2023-06-12T16:33:44","guid":{"rendered":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/?p=11588"},"modified":"2023-06-12T12:33:44","modified_gmt":"2023-06-12T16:33:44","slug":"may-2023-release-pgap","status":"publish","type":"post","link":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/06\/12\/may-2023-release-pgap\/","title":{"rendered":"New! May 2023 Release of Stand-Alone PGAP"},"content":{"rendered":"
We are happy to announce the release of a new version<\/a> of the stand-alone Prokaryotic Genome Annotation Pipeline<\/a> (PGAP) with many exciting new features.<\/p>\n This version has an improved user interface that takes the genome FASTA file and associated organism name directly on the command line. For example, to annotate a Vibrio cholerae<\/em> genome sequence in the file Vchol.fasta:<\/p>\n pgap.py -r -g Vchol.fasta -s 'Vibrio cholerae' -o Vchol.annot<\/tt><\/p>\n For more details visit our Quick Start<\/a> page. <\/p>\n In addition to the GFF<\/span>, GenBank, and protein FASTA annotation files that PGAP has always produced, it now provides:<\/p>\n PGAP assigns function to predicted proteins based on hits to Protein Family Models<\/a>, such as protein profile HMMs, Blast hits, and domain architectures. New in this release, GO terms<\/a> and Enzyme Commision (EC) numbers<\/a> associated with domain architectures are inherited by the annotated proteins. On average, 50% of proteins annotated on a genome are annotated with at least one GO term.<\/p>\n And, as every previous release, this release comes with incremental improvements by expert curators of the Protein Family Model collection that drives the precision of PGAP\u2019s structural and functional annotation.<\/p>\n Follow us on Twitter\u202f<\/span>@NCBI<\/span><\/a>\u202fand<\/span>\u00a0j<\/span>oin our mailing list<\/span><\/a> to keep up to date with PGAP and other NCBI news.<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n Please try this new version and share your experience<\/a> with us.<\/p>\n","protected":false},"excerpt":{"rendered":" We are happy to announce the release of a new version of the stand-alone Prokaryotic Genome Annotation Pipeline (PGAP) with many exciting new features. Improved user interface This version has an improved user interface that takes the genome FASTA file and associated organism name directly on the command line. For example, to annotate a Vibrio … Continue reading New! May 2023 Release of Stand-Alone PGAP<\/span> Improved user interface<\/h5>\n
Additional output files for better interoperability<\/h5>\n
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More Gene Ontology (GO) terms in the annotation<\/h5>\n
Stay up to date<\/h5>\n
We want to hear from you!<\/h5>\n