{"id":11335,"date":"2023-05-09T11:00:07","date_gmt":"2023-05-09T15:00:07","guid":{"rendered":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/?p=11335"},"modified":"2023-05-09T11:00:07","modified_gmt":"2023-05-09T15:00:07","slug":"refseq-release-218","status":"publish","type":"post","link":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/05\/09\/refseq-release-218\/","title":{"rendered":"RefSeq Release 218"},"content":{"rendered":"<div id=\"activitymodule\" class=\"module toggle-wrap\">\n<div class=\"mod-content\">\n<div class=\"issuePanelWrapper\">\n<div id=\"issue_actions_container\" class=\"issuePanelContainer bbb-gp-ellipsis-calculated\">\n<div id=\"comment-7114346\" class=\"issue-data-block activity-comment twixi-block expanded\">\n<div class=\"twixi-wrap verbose actionContainer\">\n<div class=\"action-body flooded\">\n<p>RefSeq release 218 is now available <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/refseq\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">online<\/a>\u00a0and from the\u00a0<a href=\"https:\/\/ftp.ncbi.nlm.nih.gov\/refseq\/release\/\">FTP<\/a>\u00a0site. You can access RefSeq data through\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">NCBI Datasets<\/a>.<\/p>\n<h4>What\u2019s included in this release?<\/h4>\n<p>As of May 1, 2023, this full release incorporates genomic, transcript, and protein data containing:<\/p>\n<ul>\n<li>356,619,635 records<\/li>\n<li>260,776,371 proteins<\/li>\n<li>52,503,423 RNAs<\/li>\n<li>sequences from 133,740 organisms <!--more--><\/li>\n<\/ul>\n<p>The release is provided in several directories as a complete dataset and divided by logical groupings.<span id=\"more-10930\"><\/span><span id=\"more-10489\"><\/span><\/p>\n<h4>Updates &amp; announcements<\/h4>\n<p><b>New annotation milestone!<\/b><\/p>\n<p>We are excited to announce that we have annotated over <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genome\/annotation_euk\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">1,000 eukaryotic species in RefSeq<\/a>!<\/p>\n<p><b>Human genome annotation update<\/b><\/p>\n<ul>\n<li>Assembly GRCh38.p14: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genome\/annotation_euk\/Homo_sapiens\/GCF_000001405.40-RS_2023_03\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">Annotation Release GCF_000001405.40-RS_2023_03<\/a> is an update of NCBI Homo sapiens Annotation Release 110.<\/li>\n<li>Assembly T2T-CHM13v2.0: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genome\/annotation_euk\/Homo_sapiens\/GCF_009914755.1-RS_2023_03\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">Annotation Release GCF_009914755.1-RS_2023_03<\/a> is an update of NCBI Homo sapiens Annotation Release 110.<\/li>\n<\/ul>\n<p><b>Mouse annotation update<\/b><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genome\/annotation_euk\/Mus_musculus\/GCF_000001635.27-RS_2023_04\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">Annotation Release GCF_000001635.27-RS_2023_04<\/a> is an update of NCBI Mus musculus Annotation Release 109.<\/p>\n<p><b>New eukaryotic genome annotations<\/b><\/p>\n<p>This release includes new annotations generated by NCBI&#8217;s eukaryotic genome annotation pipeline for 55 other species, including:<\/p>\n<ul>\n<li>Siamang, based on new assembly NHGRI_mSymSyn1-v1.1-hic.freeze_pri (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/genome\/GCF_028878055.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">GCF_028878055.1-RS_2023_03<\/a>)<\/li>\n<li>Iberian mole. based on updated assembly MPIMG_talOcc4v2.1 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/genome\/GCF_014898055.3\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">GCF_014898055.3-RS_2023_03<\/a>)<\/li>\n<li>Fat sand rat, based on new assembly mPsaObe1.curated_primary_1811 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/genome\/GCF_907164565.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">GCF_907164565.1-RS_2023_04<\/a>)<\/li>\n<li>Whooping crane, based on new assembly mPsaObe1.curated_primary_1811 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/genome\/GCF_028858705.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">GCF_028858705.1-RS_2023_03<\/a>) <em>(pictured)<\/em><\/li>\n<li>Oriental weatherfish, based on new assembly HAU_Mang_1.0 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/genome\/GCF_027580225.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">GCF_027580225.1-RS_2023_04<\/a>)<\/li>\n<li>Melon fly, based on new assembly idZeuCucr1.2 (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/genome\/GCF_028554725.1\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">GCF_028554725.1-RS_2023_03<\/a>)<\/li>\n<\/ul>\n<h4>Stay up to date<\/h4>\n<p>RefSeq supports the\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/comparative-genomics-resource\/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-218-20230509\">NIH Comparative Genomics Resource (CGR)<\/a>, an NLM project to establish an ecosystem to facilitate reliable comparative genomics analyses\u202ffor all eukaryotic organisms. <span class=\"TextRun Highlight SCXW148001688 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW148001688 BCX8\">Follow us on Twitter\u202f<\/span><\/span><a class=\"Hyperlink SCXW148001688 BCX8\" href=\"https:\/\/twitter.com\/ncbi\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"TextRun Highlight SCXW148001688 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW148001688 BCX8\" data-ccp-charstyle=\"Hyperlink\">@NCBI<\/span><\/span><\/a> and\u00a0<a class=\"external-link\" href=\"https:\/\/public.govdelivery.com\/accounts\/USNLMOCPL\/subscriber\/new?topic_id=USNLMOCPL_50%22\" rel=\"nofollow\">join our mailing list<\/a> to keep up to date with RefSeq and other CGR news.<\/p>\n<h4>Questions?<\/h4>\n<p><span data-contrast=\"auto\">If you have questions or would like to provide feedback, please reach out to us at\u00a0<\/span><a href=\"mailto:info@ncbi.nlm.nih.gov\"><span data-contrast=\"none\">info@ncbi.nlm.nih.gov<\/span><\/a><span data-contrast=\"auto\">.\u00a0<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"addcomment\" class=\"module\">\n<div id=\"addcomment-inner\" class=\"module\">\n<div class=\"mod-footer\">\n<p><a id=\"footer-comment-button\" class=\"aui-button\" href=\"https:\/\/jira.ncbi.nlm.nih.gov\/secure\/AddComment!default.jspa?id=1782334\" name=\"add-comment\"><\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>RefSeq release 218 is now available online\u00a0and from the\u00a0FTP\u00a0site. You can access RefSeq data through\u00a0NCBI Datasets. What\u2019s included in this release? As of May 1, 2023, this full release incorporates genomic, transcript, and protein data containing: 356,619,635 records 260,776,371 proteins 52,503,423 RNAs sequences from 133,740 organisms<\/p>\n","protected":false},"author":42204617,"featured_media":11347,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2248],"tags":[693060768,693060686,574294629,34457,27739816],"table_tags":[],"class_list":["post-11335","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-whats-new","tag-comparative-genomics-resource-cgr","tag-datasets","tag-eukaryotic-genome-annotation","tag-taxonomy","tag-refseq"],"jetpack_publicize_connections":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>RefSeq Release 218 - NCBI Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/05\/09\/refseq-release-218\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"RefSeq Release 218 - NCBI Insights\" \/>\n<meta property=\"og:description\" content=\"RefSeq release 218 is now available online\u00a0and from the\u00a0FTP\u00a0site. 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